Project measure / variable:   Metten1   line_doseA_30min

ID, description, units MPD:16504   line_doseA_30min   line crossings, 2.75 g/kg i.p.   [n]  30min after  
ethanol study
Data set, strains Metten1   inbred   9 strains     sex: both     age: 8-11wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Metten1 - line crossings, 2.75 g/kg i.p. 30min after



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means12.9   n 9.49   n
Median of the strain means14.0   n 9.00   n
SD of the strain means± 7.50 ± 5.78
Coefficient of variation (CV)0.580 0.609
Min–max range of strain means5.25   –   28.5   n 0   –   17.2   n
Mean sample size per strain4.4   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 245.0567 245.0567 2.673 0.1072
strain 8 2355.9806 294.4976 3.2123 0.0041
sex:strain 8 723.6048 90.4506 0.9866 0.4553
Residuals 61 5592.3452 91.6778


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 7.33 9.45   3 5.46 1.29 -0.75
129P3/J m 8.0 4.0   3 2.31 0.5 4.0, 12.0 -0.26
129S1/SvImJ f 5.75 6.95   4 3.47 1.21 -0.96
129S1/SvImJ m 0.0 0.0   4 0.0 0.0 -1.64
A/J f 19.0 18.0   3 10.4 0.947 1.0, 37.0 0.81
A/J m 13.8 9.43   4 4.71 0.686 1.0, 23.0 0.75
BALB/cByJ f 14.0 7.87   6 3.21 0.562 1.0, 24.0 0.14
BALB/cByJ m 17.2 5.81   6 2.37 0.338 10.0, 24.0 1.33
BTBR T+ Itpr3tf/J f 14.0 16.1   4 8.05 1.15 0.14
BTBR T+ Itpr3tf/J m 9.0 9.7   4 4.85 1.08 2.0, 23.0 -0.08
C3H/HeJ f 5.25 6.08   4 3.04 1.16 -1.02
C3H/HeJ m 7.0 8.72   4 4.36 1.25 -0.43
C57BL/6J f 14.5 5.68   6 2.32 0.392 6.0, 21.0 0.21
C57BL/6J m 2.71 2.06   7 0.778 0.758 -1.17
DBA/2J f 8.0 7.51   7 2.84 0.938 1.0, 23.0 -0.66
DBA/2J m 12.0 18.2   3 10.5 1.52 0.43
FVB/NJ f 28.5 10.7   4 5.33 0.374 17.0, 39.0 2.08
FVB/NJ m 15.7 21.4   3 12.3 1.36 1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 7.3333 5.528 18.3873 -3.7207
129P3/J m 8.0 5.528 19.054 -3.054
129S1/SvImJ f 5.75 4.7874 15.323 -3.823
129S1/SvImJ m 0.0 4.7874 9.573 -9.573
A/J f 19.0 5.528 30.054 7.946
A/J m 13.75 4.7874 23.323 4.177
BALB/cByJ f 14.0 3.9089 21.8164 6.1836
BALB/cByJ m 17.1667 3.9089 24.983 9.3503
BTBR T+ Itpr3tf/J f 14.0 4.7874 23.573 4.427
BTBR T+ Itpr3tf/J m 9.0 4.7874 18.573 -0.573
C3H/HeJ f 5.25 4.7874 14.823 -4.323
C3H/HeJ m 7.0 4.7874 16.573 -2.573
C57BL/6J f 14.5 3.9089 22.3164 6.6836
C57BL/6J m 2.7143 3.619 9.9508 -4.5223
DBA/2J f 8.0 3.619 15.2365 0.7635
DBA/2J m 12.0 5.528 23.054 0.946
FVB/NJ f 28.5 4.7874 38.073 18.927
FVB/NJ m 15.6667 5.528 26.7207 4.6127


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 7.6667 3.9089 15.483 -0.1497
129S1/SvImJ both 2.875 3.3852 9.6442 -3.8942
A/J both 16.375 3.6565 23.6865 9.0635
BALB/cByJ both 15.5833 2.764 21.1103 10.0563
BTBR T+ Itpr3tf/J both 11.5 3.3852 18.2692 4.7308
C3H/HeJ both 6.125 3.3852 12.8942 -0.6442
C57BL/6J both 8.6071 2.6635 13.9331 3.2812
DBA/2J both 10.0 3.3036 16.606 3.394
FVB/NJ both 22.0833 3.6565 29.3949 14.7718




  GWAS USING LINEAR MIXED MODELS