Project measure / variable:   Metten1   line_doseA_10min


  STRAIN COMPARISON PLOT
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Metten1 - line crossings, 2.75 g/kg i.p. 10min after injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means9.85   n 8.35   n
Median of the strain means10.0   n 6.00   n
SD of the strain means± 6.12 ± 7.39
Coefficient of variation (CV)0.621 0.885
Min–max range of strain means0   –   22.0   n 0.667   –   22.0   n
Mean sample size per strain4.7   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 53.0985 53.0985 0.4329 0.513
strain 8 2473.1498 309.1437 2.5203 0.0191
sex:strain 8 439.238 54.9048 0.4476 0.8876
Residuals 63 7727.7976 122.6635


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 0.0 0.0   3 0.0 0.0 -1.61
129P3/J m 0.667 1.15   3 0.667 1.73 -1.04
129S1/SvImJ f 3.5 5.74   4 2.87 1.64 -1.04
129S1/SvImJ m 2.0 4.0   4 2.0 2.0 -0.86
A/J f 10.0 12.6   4 6.28 1.26 0.02
A/J m 7.75 2.99   4 1.49 0.385 4.0, 11.0 -0.08
BALB/cByJ f 11.3 9.67   7 3.66 0.857 0.24
BALB/cByJ m 15.3 15.2   6 6.21 0.991 0.94
BTBR T+ Itpr3tf/J f 12.0 16.1   4 8.04 1.34 0.35
BTBR T+ Itpr3tf/J m 6.0 10.4   3 6.0 1.73 -0.32
C3H/HeJ f 12.2 15.2   4 7.58 1.24 0.38
C3H/HeJ m 2.75 2.99   4 1.49 1.09 -0.76
C57BL/6J f 8.83 5.49   6 2.24 0.622 -0.17
C57BL/6J m 3.71 3.55   7 1.34 0.955 -0.63
DBA/2J f 8.86 9.15   7 3.46 1.03 1.0, 27.0 -0.16
DBA/2J m 15.0 20.2   3 11.7 1.35 0.9
FVB/NJ f 22.0 21.1   4 10.5 0.957 1.99
FVB/NJ m 22.0 16.1   4 8.04 0.731 12.0, 46.0 1.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 0.0 6.3944 12.7781 -12.7781
129P3/J m 0.6667 6.3944 13.4448 -12.1114
129S1/SvImJ f 3.5 5.5377 14.5662 -7.5662
129S1/SvImJ m 2.0 5.5377 13.0662 -9.0662
A/J f 10.0 5.5377 21.0662 -1.0662
A/J m 7.75 5.5377 18.8162 -3.3162
BALB/cByJ f 11.2857 4.1861 19.6509 2.9205
BALB/cByJ m 15.3333 4.5215 24.3688 6.2978
BTBR T+ Itpr3tf/J f 12.0 5.5377 23.0662 0.9338
BTBR T+ Itpr3tf/J m 6.0 6.3944 18.7781 -6.7781
C3H/HeJ f 12.25 5.5377 23.3162 1.1838
C3H/HeJ m 2.75 5.5377 13.8162 -8.3162
C57BL/6J f 8.8333 4.5215 17.8688 -0.2022
C57BL/6J m 3.7143 4.1861 12.0795 -4.6509
DBA/2J f 8.8571 4.1861 17.2224 0.4919
DBA/2J m 15.0 6.3944 27.7781 2.2219
FVB/NJ f 22.0 5.5377 33.0662 10.9338
FVB/NJ m 22.0 5.5377 33.0662 10.9338


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 0.3333 4.5215 9.3688 -8.7022
129S1/SvImJ both 2.75 3.9157 10.575 -5.075
A/J both 8.875 3.9157 16.7 1.05
BALB/cByJ both 13.3095 3.0809 19.4662 7.1529
BTBR T+ Itpr3tf/J both 9.0 4.2295 17.4519 0.5481
C3H/HeJ both 7.5 3.9157 15.325 -0.325
C57BL/6J both 6.2738 3.0809 12.4305 0.1172
DBA/2J both 11.9286 3.8214 19.565 4.2922
FVB/NJ both 22.0 3.9157 29.825 14.175




GWAS analysis not available: At least 12 strains are required