Project measure / variable:   Metten1   line_doseA_pre

ID, description, units MPD:16501   line_doseA_pre   line crossings, 2.75 g/kg i.p.   [n]  pre-injection  
ethanol study
Data set, strains Metten1   inbred   9 strains     sex: both     age: 8-11wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Metten1 - line crossings, 2.75 g/kg i.p. pre-injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means11.6   n 9.02   n
Median of the strain means9.00   n 8.33   n
SD of the strain means± 6.53 ± 6.41
Coefficient of variation (CV)0.560 0.711
Min–max range of strain means3.75   –   21.8   n 2.00   –   23.2   n
Mean sample size per strain4.7   mice 4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 76.5742 76.5742 3.2314 0.077
strain 8 2541.1425 317.6428 13.4042 < 0.0001
sex:strain 8 202.5545 25.3193 1.0685 0.3963
Residuals 64 1516.619 23.6972


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 20.3 4.04   3 2.33 0.199 16.0, 24.0 1.33
129P3/J m 12.0 0.0   2   0.0 0.0 12.0, 12.0 0.46
129S1/SvImJ f 7.0 5.35   4 2.68 0.765 1.0, 12.0 -0.71
129S1/SvImJ m 4.5 4.04   4 2.02 0.898 1.0, 8.0 -0.7
A/J f 3.75 1.26   4 0.629 0.336 2.0, 5.0 -1.21
A/J m 2.75 3.59   4 1.8 1.31 -0.98
BALB/cByJ f 8.43 6.0   7 2.27 0.711 -0.49
BALB/cByJ m 8.33 6.62   6 2.7 0.795 1.0, 20.0 -0.11
BTBR T+ Itpr3tf/J f 21.8 7.93   4 3.97 0.365 15.0, 32.0 1.56
BTBR T+ Itpr3tf/J m 23.2 4.43   4 2.21 0.19 19.0, 28.0 2.21
C3H/HeJ f 9.0 5.23   4 2.61 0.581 4.0, 14.0 -0.41
C3H/HeJ m 10.8 4.43   4 2.21 0.412 6.0, 15.0 0.28
C57BL/6J f 14.2 4.54   6 1.85 0.32 7.0, 19.0 0.39
C57BL/6J m 10.6 5.53   7 2.09 0.523 1.0, 16.0 0.25
DBA/2J f 5.14 2.04   7 0.769 0.396 2.0, 8.0 -1.0
DBA/2J m 2.0 0.0   4 0.0 0.0 2.0, 2.0 -1.09
FVB/NJ f 15.2 5.32   4 2.66 0.349 11.0, 22.0 0.54
FVB/NJ m 7.0 5.35   4 2.68 0.765 2.0, 13.0 -0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 20.3333 2.8105 25.948 14.7187
129P3/J m 12.0 3.4422 18.8765 5.1235
129S1/SvImJ f 7.0 2.434 11.8624 2.1376
129S1/SvImJ m 4.5 2.434 9.3624 0.0
A/J f 3.75 2.434 8.6124 0.0
A/J m 2.75 2.434 7.6124 0.0
BALB/cByJ f 8.4286 1.8399 12.1042 4.7529
BALB/cByJ m 8.3333 1.9873 12.3035 4.3632
BTBR T+ Itpr3tf/J f 21.75 2.434 26.6124 16.8876
BTBR T+ Itpr3tf/J m 23.25 2.434 28.1124 18.3876
C3H/HeJ f 9.0 2.434 13.8624 4.1376
C3H/HeJ m 10.75 2.434 15.6124 5.8876
C57BL/6J f 14.1667 1.9873 18.1368 10.1965
C57BL/6J m 10.5714 1.8399 14.2471 6.8958
DBA/2J f 5.1429 1.8399 8.8185 1.4672
DBA/2J m 2.0 2.434 6.8624 0.0
FVB/NJ f 15.25 2.434 20.1124 10.3876
FVB/NJ m 7.0 2.434 11.8624 2.1376


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 16.1667 2.2219 20.6055 11.7279
129S1/SvImJ both 5.75 1.7211 9.1883 2.3117
A/J both 3.25 1.7211 6.6883 0.0
BALB/cByJ both 8.381 1.3541 11.0862 5.6757
BTBR T+ Itpr3tf/J both 22.5 1.7211 25.9383 19.0617
C3H/HeJ both 9.875 1.7211 13.3133 6.4367
C57BL/6J both 12.369 1.3541 15.0743 9.6638
DBA/2J both 3.5714 1.5256 6.6191 0.5237
FVB/NJ both 11.125 1.7211 14.5633 7.6867




  GWAS USING LINEAR MIXED MODELS