Project measure / variable:   Crabbe3   ARR1_post_30rpm

ID, description, units MPD:15846   ARR1_post_30rpm   latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1)   [s]  ethanol  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) ethanol



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means25.9   s 28.6   s
Median of the strain means27.9   s 26.1   s
SD of the strain means± 10.5 ± 9.41
Coefficient of variation (CV)0.403 0.329
Min–max range of strain means8.14   –   40.0   s 15.3   –   42.7   s
Mean sample size per strain4.6   mice 4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 100.4575 100.4575 0.483 0.4899
strain 7 4982.4463 711.778 3.4222 0.0041
sex:strain 7 1093.4793 156.2113 0.7511 0.6301
Residuals 56 11647.2733 207.987


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.14 1.21   5 0.542 0.149 6.8, 9.7 -1.7
129S1/SvImJ m 24.7 16.7   5 7.48 0.677 6.4, 50.3 -0.42
A/J f 26.2 12.2   5 5.46 0.466 8.7, 40.3 0.02
A/J m 24.8 8.69   5 3.89 0.35 11.3, 34.2 -0.4
BALB/cByJ f 30.7 20.3   5 9.09 0.662 7.8, 63.3 0.46
BALB/cByJ m 41.9 7.35   3 4.24 0.175 33.6, 47.5 1.41
BTBR T+ Itpr3tf/J f 40.0 12.7   3 7.31 0.316 30.1, 54.3 1.35
BTBR T+ Itpr3tf/J m 29.5 31.7   2   22.4 1.07 7.1, 51.9 0.09
C3H/HeJ f 19.4 7.44   5 3.33 0.384 10.4, 29.1 -0.63
C3H/HeJ m 15.3 8.64   5 3.86 0.564 8.7, 29.6 -1.41
C57BL/6J f 35.9 18.1   5 8.1 0.504 4.9, 51.5 0.95
C57BL/6J m 42.7 24.1   5 10.8 0.564 19.4, 83.3 1.5
DBA/2J f 17.5 7.06   4 3.53 0.403 9.6, 25.4 -0.81
DBA/2J m 22.6 12.6   5 5.62 0.556 6.8, 34.0 -0.64
FVB/NJ f 29.7 13.0   5 5.84 0.44 13.3, 47.3 0.36
FVB/NJ m 27.4 15.2   5 6.82 0.557 12.9, 45.3 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.14 6.4496 21.0601 0.0
129S1/SvImJ m 24.7 6.4496 37.6201 11.7799
A/J f 26.22 6.4496 39.1401 13.2999
A/J m 24.82 6.4496 37.7401 11.8999
BALB/cByJ f 30.68 6.4496 43.6001 17.7599
BALB/cByJ m 41.9333 8.3264 58.6131 25.2535
BTBR T+ Itpr3tf/J f 40.0333 8.3264 56.7131 23.3535
BTBR T+ Itpr3tf/J m 29.5 10.1977 49.9285 9.0715
C3H/HeJ f 19.36 6.4496 32.2801 6.4399
C3H/HeJ m 15.3 6.4496 28.2201 2.3799
C57BL/6J f 35.94 6.4496 48.8601 23.0199
C57BL/6J m 42.68 6.4496 55.6001 29.7599
DBA/2J f 17.5 7.2109 31.9451 3.0549
DBA/2J m 22.58 6.4496 35.5001 9.6599
FVB/NJ f 29.66 6.4496 42.5801 16.7399
FVB/NJ m 27.36 6.4496 40.2801 14.4399


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 16.42 4.5606 25.5559 7.2841
A/J both 25.52 4.5606 34.6559 16.3841
BALB/cByJ both 36.3067 5.2661 46.8559 25.7574
BTBR T+ Itpr3tf/J both 34.7667 6.5826 47.9532 21.5801
C3H/HeJ both 17.33 4.5606 26.4659 8.1941
C57BL/6J both 39.31 4.5606 48.4459 30.1741
DBA/2J both 20.04 4.8372 29.7301 10.3499
FVB/NJ both 28.51 4.5606 37.6459 19.3741




  GWAS USING LINEAR MIXED MODELS