Project measure / variable:   Crabbe3   FS_3rpm_EtOH_1

ID, description, units MPD:15810   FS_3rpm_EtOH_1   latency to fall, fixed speed 3 rpm rotarod   [s]  dose: 1 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   9 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 3 rpm rotarod dose: 1 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means153   s 148   s
Median of the strain means151   s 152   s
SD of the strain means± 27.5 ± 23.9
Coefficient of variation (CV)0.179 0.161
Min–max range of strain means90.5   –   180   s 114   –   180   s
Mean sample size per strain3.9   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 98.864 98.864 0.0502 0.8237
strain 8 24020.729 3002.5911 1.5242 0.1745
sex:strain 8 10330.1136 1291.2642 0.6555 0.7272
Residuals 47 92589.055 1969.9799


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 154.0 51.8   4 25.9 0.336 76.5, 180.0 0.02
129S1/SvImJ m 138.0 73.5   3 42.4 0.534 52.7, 180.0 -0.43
A/J f 90.5 21.2   3 12.2 0.234 78.0, 115.0 -2.29
A/J m 138.0 42.4   3 24.5 0.306 95.3, 180.0 -0.43
B6D2F1/J f 178.0 5.0   4 2.5 0.0282 170.0, 180.0 0.9
B6D2F1/J m 180.0 0.0   4 0.0 0.0 180.0, 180.0 1.32
BALB/cByJ f 180.0 0.0   4 0.0 0.0 180.0, 180.0 0.97
BALB/cByJ m 180.0 0.0   4 0.0 0.0 180.0, 180.0 1.32
BTBR T+ Itpr3tf/J f 180.0 0.0   2   0.0 0.0 180.0, 180.0 0.97
BTBR T+ Itpr3tf/J m 114.0 64.0   2   45.2 0.563 68.5, 159.0 -1.43
C3H/HeJ f 150.0 60.2   4 30.1 0.402 59.5, 180.0 -0.12
C3H/HeJ m 152.0 56.0   4 28.0 0.368 68.0, 180.0 0.15
C57BL/6J f 150.0 38.7   4 19.4 0.259 99.0, 180.0 -0.12
C57BL/6J m 159.0 41.3   4 20.7 0.259 97.4, 180.0 0.45
DBA/2J f 147.0 65.6   4 32.8 0.446 48.8, 180.0 -0.23
DBA/2J m 117.0 42.4   4 21.2 0.363 92.4, 180.0 -1.31
FVB/NJ f 151.0 58.9   4 29.5 0.392 62.1, 180.0 -0.09
FVB/NJ m 157.0 46.4   4 23.2 0.296 87.2, 180.0 0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 154.125 22.1922 198.77 109.48
129S1/SvImJ m 137.5667 25.6254 189.1183 86.0151
A/J f 90.5333 25.6254 142.0849 38.9817
A/J m 138.4333 25.6254 189.9849 86.8817
B6D2F1/J f 177.5 22.1922 222.145 132.855
B6D2F1/J m 180.0 22.1922 224.645 135.355
BALB/cByJ f 180.0 22.1922 224.645 135.355
BALB/cByJ m 180.0 22.1922 224.645 135.355
BTBR T+ Itpr3tf/J f 180.0 31.3845 243.1376 116.8624
BTBR T+ Itpr3tf/J m 113.75 31.3845 176.8876 50.6124
C3H/HeJ f 149.875 22.1922 194.52 105.23
C3H/HeJ m 152.0 22.1922 196.645 107.355
C57BL/6J f 149.75 22.1922 194.395 105.105
C57BL/6J m 159.35 22.1922 203.995 114.705
DBA/2J f 147.2 22.1922 191.845 102.555
DBA/2J m 116.725 22.1922 161.37 72.08
FVB/NJ f 150.525 22.1922 195.17 105.88
FVB/NJ m 156.8 22.1922 201.445 112.155


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 145.8458 16.9496 179.944 111.7476
A/J both 114.4833 18.1199 150.9358 78.0308
B6D2F1/J both 178.75 15.6923 210.3188 147.1812
BALB/cByJ both 180.0 15.6923 211.5688 148.4312
BTBR T+ Itpr3tf/J both 146.875 22.1922 191.52 102.23
C3H/HeJ both 150.9375 15.6923 182.5063 119.3687
C57BL/6J both 154.55 15.6923 186.1188 122.9812
DBA/2J both 131.9625 15.6923 163.5313 100.3937
FVB/NJ both 153.6625 15.6923 185.2313 122.0937




  GWAS USING LINEAR MIXED MODELS