Project measure / variable:   Crabbe1   grid_ataxia_doseF

ID, description, units MPD:15422   grid_ataxia_doseF   grid habituation, missteps per cm   [n/cm]  dose 2.5 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure grid test
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  STRAIN COMPARISON PLOT
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Crabbe1 - grid habituation, missteps per cm dose 2.5 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.387   n/cm 0.312   n/cm
Median of the strain means0.383   n/cm 0.289   n/cm
SD of the strain means± 0.139 ± 0.138
Coefficient of variation (CV)0.358 0.443
Min–max range of strain means0.191   –   0.587   n/cm 0.0650   –   0.478   n/cm
Mean sample size per strain2.6   mice 2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0185 0.0185 0.2285 0.6379
strain 3 0.2055 0.0685 0.8454 0.4852
sex:strain 3 0.1146 0.0382 0.4715 0.7055
Residuals 20 1.6209 0.081


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.509 0.00141   2   0.001 0.00278 0.508, 0.51 0.88
A/J f 0.44 0.0   1   0.0 0.0 0.44, 0.44 0.38
A/J m 0.289 0.0   1   0.0 0.0 0.289, 0.289 -0.17
BALB/cByJ f 0.191 0.137   4 0.0683 0.715 0.058, 0.378 -1.41
BALB/cByJ m 0.264 0.17   3 0.0979 0.643 0.087, 0.425 -0.35
BTBR T+ Itpr3tf/J m 0.285 0.272   3 0.157 0.953 0.069, 0.59 -0.19
C3H/HeJ f 0.587 0.221   2   0.156 0.377 0.43, 0.743 1.44
C3H/HeJ m 0.344 0.477   3 0.275 1.39 0.054, 0.894 0.23
C57BL/6J f 0.255 0.0   1   0.0 0.0 0.255, 0.255 -0.95
C57BL/6J m 0.065 0.0   1   0.0 0.0 0.065, 0.065 -1.79
DBA/2J f 0.383 0.32   4 0.16 0.836 0.044, 0.814 -0.03
DBA/2J m 0.478 0.237   4 0.119 0.496 0.264, 0.791 1.2
FVB/NJ f 0.344 0.257   4 0.128 0.745 0.005, 0.607 -0.31
FVB/NJ m 0.458 0.332   4 0.166 0.725 0.004, 0.799 1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 0.191 0.1423 0.4879 0.0
BALB/cByJ m 0.2637 0.1644 0.6065 0.0
C3H/HeJ f 0.5865 0.2013 1.0064 0.1666
C3H/HeJ m 0.3437 0.1644 0.6865 0.0008
DBA/2J f 0.3827 0.1423 0.6797 0.0858
DBA/2J m 0.478 0.1423 0.7749 0.1811
FVB/NJ f 0.3445 0.1423 0.6414 0.0476
FVB/NJ m 0.458 0.1423 0.7549 0.1611


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 0.2273 0.1087 0.4541 0.0006
C3H/HeJ both 0.4651 0.1299 0.7361 0.194
DBA/2J both 0.4304 0.1006 0.6403 0.2204
FVB/NJ both 0.4012 0.1006 0.6112 0.1913




  GWAS USING LINEAR MIXED MODELS