Project measure / variable:   Crabbe1   grid_ataxia_doseE

ID, description, units MPD:15420   grid_ataxia_doseE   grid habituation, missteps per cm   [n/cm]  dose 2.0 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure grid test
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  STRAIN COMPARISON PLOT
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Crabbe1 - grid habituation, missteps per cm dose 2.0 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means0.203   n/cm 0.237   n/cm
Median of the strain means0.186   n/cm 0.198   n/cm
SD of the strain means± 0.0817 ± 0.151
Coefficient of variation (CV)0.402 0.639
Min–max range of strain means0.0935   –   0.344   n/cm 0.107   –   0.578   n/cm
Mean sample size per strain3.4   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0195 0.0195 0.7437 0.3942
strain 6 0.4866 0.0811 3.0871 0.0153
sex:strain 6 0.1408 0.0235 0.8935 0.5101
Residuals 36 0.9458 0.0263


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.15 0.0332   2   0.0235 0.221 0.127, 0.174 -0.58
A/J f 0.344 0.108   3 0.0625 0.315 0.221, 0.425 1.72
A/J m 0.578 0.43   3 0.248 0.744 0.15, 1.01 2.25
BALB/cByJ f 0.172 0.134   4 0.0671 0.779 0.017, 0.319 -0.38
BALB/cByJ m 0.229 0.101   4 0.0504 0.44 0.078, 0.282 -0.05
BTBR T+ Itpr3tf/J f 0.273 0.0708   4 0.0354 0.259 0.183, 0.356 0.85
BTBR T+ Itpr3tf/J m 0.128 0.0805   4 0.0402 0.627 0.024, 0.21 -0.72
C3H/HeJ f 0.158 0.133   3 0.0768 0.842 0.008, 0.262 -0.55
C3H/HeJ m 0.248 0.223   4 0.111 0.898 0.046, 0.469 0.07
C57BL/6J f 0.186 0.22   2   0.155 1.18 0.031, 0.342 -0.21
C57BL/6J m 0.167 0.109   3 0.063 0.652 0.055, 0.273 -0.46
DBA/2J f 0.196 0.127   4 0.0635 0.65 0.01, 0.298 -0.09
DBA/2J m 0.29 0.187   4 0.0937 0.647 0.012, 0.419 0.35
FVB/NJ f 0.0935 0.0316   4 0.0158 0.338 0.05, 0.121 -1.34
FVB/NJ m 0.107 0.0826   4 0.0413 0.772 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 0.344 0.0936 0.5338 0.1542
A/J m 0.578 0.0936 0.7678 0.3882
BALB/cByJ f 0.1722 0.081 0.3366 0.0079
BALB/cByJ m 0.2293 0.081 0.3936 0.0649
BTBR T+ Itpr3tf/J f 0.2728 0.081 0.4371 0.1084
BTBR T+ Itpr3tf/J m 0.1282 0.081 0.2926 0.0
C3H/HeJ f 0.158 0.0936 0.3478 0.0
C3H/HeJ m 0.248 0.081 0.4124 0.0836
C57BL/6J f 0.1865 0.1146 0.4189 0.0
C57BL/6J m 0.1673 0.0936 0.3571 0.0
DBA/2J f 0.1955 0.081 0.3599 0.0311
DBA/2J m 0.2897 0.081 0.4541 0.1254
FVB/NJ f 0.0935 0.081 0.2579 0.0
FVB/NJ m 0.107 0.081 0.2714 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 0.461 0.0662 0.5952 0.3268
BALB/cByJ both 0.2008 0.0573 0.317 0.0845
BTBR T+ Itpr3tf/J both 0.2005 0.0573 0.3167 0.0843
C3H/HeJ both 0.203 0.0619 0.3285 0.0775
C57BL/6J both 0.1769 0.074 0.327 0.0269
DBA/2J both 0.2426 0.0573 0.3588 0.1264
FVB/NJ both 0.1002 0.0573 0.2165 0.0




  GWAS USING LINEAR MIXED MODELS