Project measure / variable:   Crabbe1   grid_dist_doseE

ID, description, units MPD:15419   grid_dist_doseE   grid habituation, distance traveled   [cm]  dose 2.0 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure grid test
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  STRAIN COMPARISON PLOT
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Crabbe1 - grid habituation, distance traveled dose 2.0 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means1096   cm 977   cm
Median of the strain means1004   cm 1040   cm
SD of the strain means± 509 ± 563
Coefficient of variation (CV)0.464 0.576
Min–max range of strain means485   –   1976   cm 341   –   1991   cm
Mean sample size per strain3.7   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6073.9231 6073.9231 0.0217 0.8837
strain 6 10694431.5417 1782405.2569 6.3656 0.0001
sex:strain 6 1269956.6186 211659.4364 0.7559 0.6088
Residuals 38 10640265.9167 280006.9978


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 375.0 86.3   2   61.0 0.23 314.0, 436.0 -1.07
A/J f 715.0 316.0   3 182.0 0.442 352.0, 926.0 -0.75
A/J m 341.0 149.0   3 86.1 0.438 171.0, 451.0 -1.13
BALB/cByJ f 843.0 249.0   4 125.0 0.295 524.0, 1099.0 -0.5
BALB/cByJ m 1140.0 383.0   4 192.0 0.336 722.0, 1650.0 0.29
BTBR T+ Itpr3tf/J f 1004.0 274.0   4 137.0 0.273 606.0, 1230.0 -0.18
BTBR T+ Itpr3tf/J m 1300.0 366.0   4 183.0 0.282 857.0, 1700.0 0.57
C3H/HeJ f 1528.0 521.0   4 261.0 0.341 1149.0, 2282.0 0.85
C3H/HeJ m 940.0 245.0   4 122.0 0.261 631.0, 1215.0 -0.07
C57BL/6J f 485.0 235.0   3 136.0 0.485 321.0, 755.0 -1.2
C57BL/6J m 500.0 186.0   3 108.0 0.373 379.0, 715.0 -0.85
DBA/2J f 1118.0 134.0   4 67.0 0.12 918.0, 1197.0 0.04
DBA/2J m 1228.0 487.0   4 243.0 0.397 740.0, 1888.0 0.45
FVB/NJ f 1976.0 480.0   4 240.0 0.243 1479.0, 2521.0 1.73
FVB/NJ m 1991.0 1473.0   4 737.0 0.74 1039.0, 4146.0 1.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 715.3333 305.5089 1333.8037 96.863
A/J m 340.6667 305.5089 959.137 0.0
BALB/cByJ f 843.0 264.5784 1378.611 307.389
BALB/cByJ m 1139.75 264.5784 1675.361 604.139
BTBR T+ Itpr3tf/J f 1004.25 264.5784 1539.861 468.639
BTBR T+ Itpr3tf/J m 1299.5 264.5784 1835.111 763.889
C3H/HeJ f 1527.75 264.5784 2063.361 992.139
C3H/HeJ m 940.25 264.5784 1475.861 404.639
C57BL/6J f 485.3333 305.5089 1103.8037 0.0
C57BL/6J m 500.3333 305.5089 1118.8037 0.0
DBA/2J f 1118.5 264.5784 1654.111 582.889
DBA/2J m 1227.75 264.5784 1763.361 692.139
FVB/NJ f 1975.75 264.5784 2511.361 1440.139
FVB/NJ m 1991.25 264.5784 2526.861 1455.639


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 528.0 216.0274 965.3246 90.6754
BALB/cByJ both 991.375 187.0852 1370.1092 612.6408
BTBR T+ Itpr3tf/J both 1151.875 187.0852 1530.6092 773.1408
C3H/HeJ both 1234.0 187.0852 1612.7342 855.2658
C57BL/6J both 492.8333 216.0274 930.1579 55.5087
DBA/2J both 1173.125 187.0852 1551.8592 794.3908
FVB/NJ both 1983.5 187.0852 2362.2342 1604.7658




  GWAS USING LINEAR MIXED MODELS