Project measure / variable:   Crabbe1   grid_ataxia_doseD

ID, description, units MPD:15418   grid_ataxia_doseD   grid habituation, missteps per cm   [n/cm]  dose 1.5 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure grid test
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  STRAIN COMPARISON PLOT
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Crabbe1 - grid habituation, missteps per cm dose 1.5 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.0804   n/cm 0.103   n/cm
Median of the strain means0.0754   n/cm 0.0946   n/cm
SD of the strain means± 0.0653 ± 0.0377
Coefficient of variation (CV)0.812 0.366
Min–max range of strain means0.0192   –   0.230   n/cm 0.0622   –   0.169   n/cm
Mean sample size per strain3.5   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.006 0.006 1.2184 0.2763
strain 7 0.0921 0.0132 2.6784 0.0226
sex:strain 7 0.0293 0.0042 0.8525 0.5515
Residuals 40 0.1965 0.0049


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0813 0.111   3 0.0643 1.37 0.016, 0.21 0.01
129S1/SvImJ m 0.169 0.223   2   0.157 1.32 0.011, 0.326 1.76
A/J f 0.23 0.122   3 0.0704 0.531 0.089, 0.303 2.29
A/J m 0.148 0.115   3 0.0664 0.775 0.032, 0.262 1.2
BALB/cByJ f 0.086 0.0227   4 0.0113 0.264 0.061, 0.116 0.09
BALB/cByJ m 0.0742 0.0579   4 0.0289 0.779 0.008, 0.129 -0.76
BTBR T+ Itpr3tf/J f 0.0192 0.0146   4 0.0073 0.758 -0.94
BTBR T+ Itpr3tf/J m 0.0737 0.00945   3 0.00546 0.128 0.063, 0.081 -0.77
C3H/HeJ f 0.0353 0.0242   3 0.014 0.685 0.008, 0.054 -0.69
C3H/HeJ m 0.106 0.077   4 0.0385 0.725 0.026, 0.178 0.08
C57BL/6J f 0.073 0.0205   3 0.0118 0.281 0.052, 0.093 -0.11
C57BL/6J m 0.09 0.0552   4 0.0276 0.613 0.02, 0.139 -0.34
DBA/2J f 0.0777 0.0218   4 0.0109 0.28 0.051, 0.1 -0.04
DBA/2J m 0.0993 0.0758   4 0.0379 0.764 0.025, 0.169 -0.09
FVB/NJ f 0.0405 0.0246   4 0.0123 0.606 0.006, 0.062 -0.61
FVB/NJ m 0.0622 0.0371   4 0.0185 0.596 0.011, 0.09 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0813 0.0405 0.1631 0.0
129S1/SvImJ m 0.1685 0.0496 0.2687 0.0683
A/J f 0.2297 0.0405 0.3115 0.1479
A/J m 0.1483 0.0405 0.2301 0.0665
BALB/cByJ f 0.086 0.035 0.1568 0.0152
BALB/cByJ m 0.0742 0.035 0.1451 0.0034
BTBR T+ Itpr3tf/J f 0.0193 0.035 0.0901 0.0
BTBR T+ Itpr3tf/J m 0.0737 0.0405 0.1555 0.0
C3H/HeJ f 0.0353 0.0405 0.1171 0.0
C3H/HeJ m 0.1062 0.035 0.1771 0.0354
C57BL/6J f 0.073 0.0405 0.1548 0.0
C57BL/6J m 0.09 0.035 0.1608 0.0192
DBA/2J f 0.0778 0.035 0.1486 0.0069
DBA/2J m 0.0993 0.035 0.1701 0.0284
FVB/NJ f 0.0405 0.035 0.1113 0.0
FVB/NJ m 0.0622 0.035 0.1331 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1249 0.032 0.1896 0.0603
A/J both 0.189 0.0286 0.2468 0.1312
BALB/cByJ both 0.0801 0.0248 0.1302 0.03
BTBR T+ Itpr3tf/J both 0.0465 0.0268 0.1006 0.0
C3H/HeJ both 0.0708 0.0268 0.1249 0.0167
C57BL/6J both 0.0815 0.0268 0.1356 0.0274
DBA/2J both 0.0885 0.0248 0.1386 0.0384
FVB/NJ both 0.0514 0.0248 0.1015 0.0013




  GWAS USING LINEAR MIXED MODELS