Project measure / variable:   Crabbe1   grid_dist_doseD

ID, description, units MPD:15417   grid_dist_doseD   grid habituation, distance traveled   [cm]  dose 1.5 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure grid test
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  STRAIN COMPARISON PLOT
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Crabbe1 - grid habituation, distance traveled dose 1.5 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1086   cm 873   cm
Median of the strain means1024   cm 921   cm
SD of the strain means± 607 ± 370
Coefficient of variation (CV)0.559 0.424
Min–max range of strain means254   –   2161   cm 248   –   1342   cm
Mean sample size per strain3.8   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 628117.9055 628117.9055 3.1975 0.081
strain 7 10783871.9455 1540553.1351 7.8423 < 0.0001
sex:strain 7 1263807.1117 180543.8731 0.9191 0.5016
Residuals 42 8250572.4167 196442.2004


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 254.0 122.0   3 70.3 0.479 114.0, 333.0 -1.37
129S1/SvImJ m 248.0 100.0   2   71.0 0.405 177.0, 319.0 -1.69
A/J f 451.0 58.3   3 33.7 0.129 389.0, 505.0 -1.05
A/J m 605.0 250.0   3 144.0 0.413 397.0, 882.0 -0.72
BALB/cByJ f 1432.0 708.0   4 354.0 0.494 811.0, 2424.0 0.57
BALB/cByJ m 933.0 347.0   4 173.0 0.372 553.0, 1330.0 0.16
BTBR T+ Itpr3tf/J f 999.0 227.0   4 114.0 0.227 804.0, 1327.0 -0.14
BTBR T+ Itpr3tf/J m 909.0 46.6   3 26.9 0.0513 879.0, 963.0 0.1
C3H/HeJ f 1050.0 468.0   4 234.0 0.445 570.0, 1670.0 -0.06
C3H/HeJ m 1051.0 466.0   4 233.0 0.444 555.0, 1599.0 0.48
C57BL/6J f 865.0 184.0   4 92.1 0.213 626.0, 1045.0 -0.36
C57BL/6J m 611.0 132.0   4 65.9 0.216 487.0, 796.0 -0.71
DBA/2J f 1472.0 676.0   4 338.0 0.459 1038.0, 2478.0 0.64
DBA/2J m 1287.0 683.0   4 341.0 0.531 492.0, 1904.0 1.12
FVB/NJ f 2161.0 612.0   4 306.0 0.283 1589.0, 3028.0 1.77
FVB/NJ m 1342.0 482.0   4 241.0 0.359 662.0, 1799.0 1.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 254.3333 255.892 770.7444 0.0
129S1/SvImJ m 248.0 313.4025 880.4718 0.0
A/J f 450.6667 255.892 967.0777 0.0
A/J m 604.6667 255.892 1121.0777 88.2556
BALB/cByJ f 1432.0 221.609 1879.2251 984.7749
BALB/cByJ m 933.0 221.609 1380.2251 485.7749
BTBR T+ Itpr3tf/J f 999.25 221.609 1446.4751 552.0249
BTBR T+ Itpr3tf/J m 909.3333 255.892 1425.7444 392.9223
C3H/HeJ f 1050.25 221.609 1497.4751 603.0249
C3H/HeJ m 1050.75 221.609 1497.9751 603.5249
C57BL/6J f 865.0 221.609 1312.2251 417.7749
C57BL/6J m 610.75 221.609 1057.9751 163.5249
DBA/2J f 1472.0 221.609 1919.2251 1024.7749
DBA/2J m 1287.25 221.609 1734.4751 840.0249
FVB/NJ f 2161.0 221.609 2608.2251 1713.7749
FVB/NJ m 1342.0 221.609 1789.2251 894.7749


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 251.1667 202.3004 659.4254 0.0
A/J both 527.6667 180.943 892.8244 162.5089
BALB/cByJ both 1182.5 156.7012 1498.7359 866.2641
BTBR T+ Itpr3tf/J both 954.2917 169.2567 1295.8655 612.7179
C3H/HeJ both 1050.5 156.7012 1366.7359 734.2641
C57BL/6J both 737.875 156.7012 1054.1109 421.6391
DBA/2J both 1379.625 156.7012 1695.8609 1063.3891
FVB/NJ both 1751.5 156.7012 2067.7359 1435.2641




  GWAS USING LINEAR MIXED MODELS