Project measure / variable:   Crabbe1   bal19_doseA

ID, description, units MPD:15414   bal19_doseA   missteps crossing 19.0 mm wide balance beam   [n]  dose 1.0 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 19.0 mm wide balance beam dose 1.0 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.58   n 1.20   n
Median of the strain means0.818   n 1.17   n
SD of the strain means± 1.87 ± 0.734
Coefficient of variation (CV)1.18 0.611
Min–max range of strain means0.268   –   5.93   n 0.402   –   2.67   n
Mean sample size per strain4.1   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.8182 2.8182 0.5828 0.4489
strain 7 90.8813 12.983 2.6848 0.0195
sex:strain 7 22.8414 3.2631 0.6748 0.6923
Residuals 49 236.9559 4.8358


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.93 7.38   4 3.69 1.25 0.67, 16.7 2.32
129S1/SvImJ m 2.67 1.0   3 0.577 0.375 1.67, 3.67 2.0
A/J f 1.17 1.73   3 1.0 1.48 0.17, 3.17 -0.22
A/J m 1.17 1.0   3 0.577 0.855 0.17, 2.17 -0.04
BALB/cByJ f 0.268 0.367   5 0.164 1.37 -0.7
BALB/cByJ m 0.668 1.16   5 0.517 1.73 -0.73
BTBR T+ Itpr3tf/J f 0.498 0.576   4 0.288 1.16 -0.58
BTBR T+ Itpr3tf/J m 0.583 1.17   4 0.583 2.0 -0.84
C3H/HeJ f 2.42 2.91   4 1.45 1.2 0.45
C3H/HeJ m 1.16 0.577   3 0.333 0.496 0.83, 1.83 -0.06
C57BL/6J f 0.752 0.688   4 0.344 0.915 -0.44
C57BL/6J m 1.75 1.71   4 0.854 0.975 0.75
DBA/2J f 0.835 1.26   4 0.632 1.51 -0.4
DBA/2J m 0.402 0.367   5 0.164 0.913 -1.09
FVB/NJ f 0.8 1.15   5 0.515 1.44 -0.42
FVB/NJ m 1.2 1.2   5 0.539 1.0 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.9275 1.0995 8.1371 3.7179
129S1/SvImJ m 2.67 1.2696 5.2214 0.1186
A/J f 1.17 1.2696 3.7214 0.0
A/J m 1.17 1.2696 3.7214 0.0
BALB/cByJ f 0.268 0.9834 2.2443 0.0
BALB/cByJ m 0.668 0.9834 2.6443 0.0
BTBR T+ Itpr3tf/J f 0.4975 1.0995 2.7071 0.0
BTBR T+ Itpr3tf/J m 0.5825 1.0995 2.7921 0.0
C3H/HeJ f 2.415 1.0995 4.6246 0.2054
C3H/HeJ m 1.1633 1.2696 3.7147 0.0
C57BL/6J f 0.7525 1.0995 2.9621 0.0
C57BL/6J m 1.7525 1.0995 3.9621 0.0
DBA/2J f 0.835 1.0995 3.0446 0.0
DBA/2J m 0.402 0.9834 2.3783 0.0
FVB/NJ f 0.8 0.9834 2.7763 0.0
FVB/NJ m 1.2 0.9834 3.1763 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.2987 0.8398 5.9863 2.6112
A/J both 1.17 0.8978 2.9741 0.0
BALB/cByJ both 0.468 0.6954 1.8655 0.0
BTBR T+ Itpr3tf/J both 0.54 0.7775 2.1024 0.0
C3H/HeJ both 1.7892 0.8398 3.4768 0.1016
C57BL/6J both 1.2525 0.7775 2.8149 0.0
DBA/2J both 0.6185 0.7376 2.1007 0.0
FVB/NJ both 1.0 0.6954 2.3975 0.0




  GWAS USING LINEAR MIXED MODELS