Project measure / variable:   Crabbe1   bal15_doseA

ID, description, units MPD:15411   bal15_doseA   missteps crossing 15.8mm wide balance beam   [n]  dose 1.0 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 15.8mm wide balance beam dose 1.0 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means2.13   n 1.99   n
Median of the strain means1.97   n 1.99   n
SD of the strain means± 0.953 ± 0.812
Coefficient of variation (CV)0.448 0.409
Min–max range of strain means1.33   –   4.25   n 0.837   –   3.50   n
Mean sample size per strain5.6   mice 5.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3782 0.3782 0.1006 0.752
strain 7 40.3008 5.7573 1.5313 0.1705
sex:strain 7 7.6723 1.096 0.2915 0.9552
Residuals 72 270.7017 3.7597


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.1 2.42   5 1.08 1.15 -0.03
129S1/SvImJ m 2.42 2.91   4 1.45 1.2 0.53
A/J f 2.38 1.84   4 0.921 0.776 0.26
A/J m 1.25 0.957   4 0.479 0.766 0.5, 2.5 -0.91
BALB/cByJ f 2.31 1.83   7 0.692 0.793 0.19
BALB/cByJ m 2.19 2.13   7 0.804 0.972 0.25
BTBR T+ Itpr3tf/J f 1.33 1.97   6 0.802 1.48 -0.84
BTBR T+ Itpr3tf/J m 2.26 1.36   5 0.609 0.601 0.34
C3H/HeJ f 4.25 4.5   4 2.25 1.06 0.5, 10.5 2.23
C3H/HeJ m 3.5 1.0   3 0.577 0.286 2.5, 4.5 1.86
C57BL/6J f 1.5 1.03   6 0.422 0.687 0.17, 3.17 -0.66
C57BL/6J m 0.837 0.816   6 0.333 0.976 0.17, 2.17 -1.41
DBA/2J f 1.83 0.816   6 0.333 0.445 0.5, 2.5 -0.31
DBA/2J m 1.79 1.58   7 0.596 0.883 -0.24
FVB/NJ f 1.33 1.43   7 0.541 1.08 -0.84
FVB/NJ m 1.64 2.35   7 0.888 1.43 -0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.098 0.8671 3.8266 0.3694
129S1/SvImJ m 2.415 0.9695 4.3477 0.4823
A/J f 2.375 0.9695 4.3077 0.4423
A/J m 1.25 0.9695 3.1827 0.0
BALB/cByJ f 2.3071 0.7329 3.7681 0.8462
BALB/cByJ m 2.1886 0.7329 3.6495 0.7276
BTBR T+ Itpr3tf/J f 1.3317 0.7916 2.9097 0.0
BTBR T+ Itpr3tf/J m 2.264 0.8671 3.9926 0.5354
C3H/HeJ f 4.25 0.9695 6.1827 2.3173
C3H/HeJ m 3.5 1.1195 5.7317 1.2683
C57BL/6J f 1.5033 0.7916 3.0814 0.0
C57BL/6J m 0.8367 0.7916 2.4147 0.0
DBA/2J f 1.8333 0.7916 3.4114 0.2553
DBA/2J m 1.7857 0.7329 3.2467 0.3248
FVB/NJ f 1.3314 0.7329 2.7924 0.0
FVB/NJ m 1.6414 0.7329 3.1024 0.1805


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.2565 0.6504 3.553 0.96
A/J both 1.8125 0.6855 3.1791 0.4459
BALB/cByJ both 2.2479 0.5182 3.2809 1.2148
BTBR T+ Itpr3tf/J both 1.7978 0.5871 2.9681 0.6275
C3H/HeJ both 3.875 0.7405 5.3511 2.3989
C57BL/6J both 1.17 0.5597 2.2858 0.0542
DBA/2J both 1.8095 0.5394 2.8848 0.7343
FVB/NJ both 1.4864 0.5182 2.5195 0.4534




  GWAS USING LINEAR MIXED MODELS