Project measure / variable:   Crabbe1   bal12_doseC

ID, description, units MPD:15410   bal12_doseC   missteps crossing 12.7mm wide balance beam   [n]  dose 1.4 g/kg i.p.  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
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  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 12.7mm wide balance beam dose 1.4 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means4.61   n 4.37   n
Median of the strain means4.49   n 4.16   n
SD of the strain means± 2.22 ± 2.52
Coefficient of variation (CV)0.482 0.575
Min–max range of strain means1.05   –   7.67   n 0   –   8.50   n
Mean sample size per strain4.4   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1244 0.1244 0.0145 0.9046
strain 4 82.9284 20.7321 2.4228 0.0616
sex:strain 4 56.3802 14.0951 1.6472 0.1786
Residuals 46 393.626 8.5571


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.73
129S1/SvImJ m 8.5 2.12   2   1.5 0.25 7.0, 10.0 1.64
A/J f 7.67 0.0   1   0.0 0.0 7.67, 7.67 1.38
A/J m 0.0 0.0   1   0.0 0.0 -1.74
BALB/cByJ f 4.81 1.68   7 0.634 0.348 2.67, 7.67 0.09
BALB/cByJ m 4.34 2.73   6 1.12 0.63 0.67, 8.67 -0.01
BTBR T+ Itpr3tf/J f 3.25 3.2   4 1.6 0.985 1.0, 8.0 -0.61
BTBR T+ Itpr3tf/J m 3.0 4.24   2   3.0 1.41 -0.55
C3H/HeJ f 5.82 7.05   2   4.98 1.21 0.83, 10.8 0.54
C3H/HeJ m 6.83 0.0   1   0.0 0.0 6.83, 6.83 0.98
C57BL/6J f 4.17 3.66   6 1.49 0.877 -0.2
C57BL/6J m 4.0 1.41   6 0.577 0.354 2.0, 6.0 -0.15
DBA/2J f 7.14 3.85   7 1.45 0.539 1.14
DBA/2J m 4.2 4.09   5 1.83 0.973 -0.07
FVB/NJ f 1.05 1.34   7 0.506 1.28 -1.6
FVB/NJ m 4.11 3.08   6 1.26 0.75 -0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ f 4.8129 1.1056 7.0384 2.5873
BALB/cByJ m 4.3367 1.1942 6.7405 1.9328
BTBR T+ Itpr3tf/J f 3.25 1.4626 6.1941 0.3059
BTBR T+ Itpr3tf/J m 3.0 2.0685 7.1636 0.0
C57BL/6J f 4.1667 1.1942 6.5705 1.7628
C57BL/6J m 4.0 1.1942 6.4039 1.5961
DBA/2J f 7.1429 1.1056 9.3684 4.9173
DBA/2J m 4.2 1.3082 6.8333 1.5667
FVB/NJ f 1.0457 1.1056 3.2713 0.0
FVB/NJ m 4.1083 1.1942 6.5122 1.7045


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cByJ both 4.5748 0.8137 6.2127 2.9368
BTBR T+ Itpr3tf/J both 3.125 1.2667 5.6747 0.5753
C57BL/6J both 4.0833 0.8444 5.7831 2.3835
DBA/2J both 5.6714 0.8564 7.3953 3.9475
FVB/NJ both 2.577 0.8137 4.215 0.9391




  GWAS USING LINEAR MIXED MODELS