Project measure / variable:   Crabbe1   grid_ataxia

ID, description, units MPD:15407   grid_ataxia   grid habituation, missteps per cm   [n/cm]  control  
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure grid test
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  STRAIN COMPARISON PLOT
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Crabbe1 - grid habituation, missteps per cm control



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.00647   n/cm 0.00843   n/cm
Median of the strain means0.00609   n/cm 0.00667   n/cm
SD of the strain means± 0.00372 ± 0.00508
Coefficient of variation (CV)0.574 0.603
Min–max range of strain means0.00150   –   0.0131   n/cm 0.00317   –   0.0187   n/cm
Mean sample size per strain11.9   mice 11.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0002 0.0002 1.7046 0.1935
strain 7 0.0027 0.0004 3.7979 0.0007
sex:strain 7 0.0006 0.0001 0.7977 0.5902
Residuals 170 0.0175 0.0001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0015 0.0052   12 0.0015 3.46 -1.34
129S1/SvImJ m 0.00564 0.0129   11 0.0039 2.3 -0.55
A/J f 0.00409 0.00476   11 0.00144 1.16 -0.64
A/J m 0.0077 0.00765   10 0.00242 0.993 -0.14
BALB/cByJ f 0.007 0.0101   12 0.00292 1.44 0.14
BALB/cByJ m 0.00317 0.00349   12 0.00101 1.1 -1.03
BTBR T+ Itpr3tf/J f 0.00375 0.0062   12 0.00179 1.65 -0.73
BTBR T+ Itpr3tf/J m 0.0103 0.01   10 0.00316 0.971 0.37
C3H/HeJ f 0.01 0.00861   12 0.00249 0.861 0.95
C3H/HeJ m 0.0119 0.0243   12 0.00703 2.04 0.68
C57BL/6J f 0.00517 0.00531   12 0.00153 1.03 -0.35
C57BL/6J m 0.00525 0.00384   12 0.00111 0.732 -0.63
DBA/2J f 0.00717 0.00395   12 0.00114 0.551 0.002, 0.016 0.19
DBA/2J m 0.00475 0.00431   12 0.00124 0.907 -0.72
FVB/NJ f 0.0131 0.0106   12 0.00307 0.812 0.001, 0.034 1.78
FVB/NJ m 0.0187 0.016   12 0.00461 0.851 2.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0015 0.0029 0.0073 0.0
129S1/SvImJ m 0.0056 0.0031 0.0117 0.0
A/J f 0.0041 0.0031 0.0101 0.0
A/J m 0.0077 0.0032 0.014 0.0014
BALB/cByJ f 0.007 0.0029 0.0128 0.0012
BALB/cByJ m 0.0032 0.0029 0.009 0.0
BTBR T+ Itpr3tf/J f 0.0037 0.0029 0.0095 0.0
BTBR T+ Itpr3tf/J m 0.0103 0.0032 0.0166 0.004
C3H/HeJ f 0.01 0.0029 0.0158 0.0042
C3H/HeJ m 0.0119 0.0029 0.0177 0.0061
C57BL/6J f 0.0052 0.0029 0.011 0.0
C57BL/6J m 0.0053 0.0029 0.011 0.0
DBA/2J f 0.0072 0.0029 0.013 0.0014
DBA/2J m 0.0048 0.0029 0.0105 0.0
FVB/NJ f 0.0131 0.0029 0.0189 0.0073
FVB/NJ m 0.0188 0.0029 0.0245 0.013


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0036 0.0021 0.0078 0.0
A/J both 0.0059 0.0022 0.0103 0.0015
BALB/cByJ both 0.0051 0.0021 0.0092 0.001
BTBR T+ Itpr3tf/J both 0.007 0.0022 0.0113 0.0027
C3H/HeJ both 0.011 0.0021 0.0151 0.0069
C57BL/6J both 0.0052 0.0021 0.0093 0.0011
DBA/2J both 0.006 0.0021 0.0101 0.0019
FVB/NJ both 0.0159 0.0021 0.02 0.0118




  GWAS USING LINEAR MIXED MODELS