Project measure / variable:   CSNA03   extinction_inactive_cc_s9

ID, description, units MPD:110417   extinction_inactive_cc_s9   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 9  
cocaine study
Data set, strains CSNA03   CC w/par   34 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains21 strains
Mean of the strain means126.5   n 231.4   n
Median of the strain means77.0   n 98.0   n
SD of the strain means± 125.4 ± 453.9
Coefficient of variation (CV)0.9916 1.9619
Min–max range of strain means4.0   –   395.0   n 0.0   –   2111.0   n
Mean sample size per strain1.6   mice 1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 466209.375 466209.375 4.3014 0.057
strain 4 2507113.5252 626778.3813 5.7828 0.0058
sex:strain 4 4033790.6415 1008447.6604 9.3042 0.0007
Residuals 14 1517407.4167 108386.244


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C57BL/6J f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.89
CC001/UncJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.95
CC001/UncJ m 272.5 82.73   2   58.5 0.3036 214.0, 331.0 0.09
CC002/UncJ f 296.7 250.7   3 144.8 0.8452 143.0, 586.0 1.36
CC003/UncJ f 395.0 0.0   1   0.0 0.0 395.0, 395.0 2.14
CC004/TauUncJ f 77.0 0.0   1   0.0 0.0 77.0, 77.0 -0.39
CC004/TauUncJ m 168.2 130.3   5 58.27 0.7746 31.0, 308.0 -0.14
CC005/TauUncJ f 42.0 0.0   1   0.0 0.0 42.0, 42.0 -0.67
CC006/TauUncJ f 77.0 0.0   1   0.0 0.0 77.0, 77.0 -0.39
CC006/TauUncJ m 124.0 0.0   1   0.0 0.0 124.0, 124.0 -0.24
CC007/UncJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.98
CC007/UncJ m 13.5 2.1213   2   1.5 0.1571 12.0, 15.0 -0.48
CC008/GeniUncJ m 28.0 0.0   1   0.0 0.0 28.0, 28.0 -0.45
CC009/UncJ f 69.0 0.0   1   0.0 0.0 69.0, 69.0 -0.46
CC011/UncJ f 137.0 106.1   2   75.0 0.7742 62.0, 212.0 0.08
CC011/UncJ m 128.5 115.3   2   81.5 0.897 47.0, 210.0 -0.23
CC012/GeniUncJ m 71.0 0.0   1   0.0 0.0 71.0, 71.0 -0.35
CC013/GeniUncJ f 365.5 57.28   2   40.5 0.1567 325.0, 406.0 1.91
CC013/GeniUncJ m 222.0 237.6   2   168.0 1.0702 54.0, 390.0 -0.02
CC018/UncJ f 168.5 0.70711   2   0.5 0.0042 168.0, 169.0 0.33
CC018/UncJ m 77.25 51.29   4 25.646 0.664 33.0, 148.0 -0.34
CC019/TauUncJ f 245.3 333.9   3 192.7 1.3608 21.0, 629.0 0.95
CC019/TauUncJ m 260.5 368.4   2   260.5 1.4142 0.06
CC023/GeniUncJ f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.94
CC023/GeniUncJ m 144.0 0.0   1   0.0 0.0 144.0, 144.0 -0.19
CC024/GeniUncJ f 127.0 0.0   1   0.0 0.0 127.0, 127.0 0.0
CC025/GeniUncJ f 333.0 0.0   1   0.0 0.0 333.0, 333.0 1.65
CC027/GeniUncJ f 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.84
CC028/GeniUncJ f 141.0 113.7   3 65.65 0.8065 11.0, 222.0 0.12
CC028/GeniUncJ m 41.0 0.0   1   0.0 0.0 41.0, 41.0 -0.42
CC030/GeniUncJ m 498.0 0.0   1   0.0 0.0 498.0, 498.0 0.59
CC032/GeniUncJ f 58.0 0.0   1   0.0 0.0 58.0, 58.0 -0.55
CC036/UncJ f 297.3 352.9   3 203.8 1.187 47.0, 701.0 1.36
CC036/UncJ m 490.0 0.0   1   0.0 0.0 490.0, 490.0 0.57
CC040/TauUncJ m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.48
CC041/TauUncJ m 0.0 0.0   1   0.0 None -0.51
CC044/UncJ f 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.9
CC044/UncJ m 98.0 0.0   1   0.0 0.0 98.0, 98.0 -0.29
CC051/TauUncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.5
CC057/UncJ f 31.0 0.0   1   0.0 0.0 31.0, 31.0 -0.76
CC059/TauUncJ f 110.0 57.66   3 33.292 0.5242 50.0, 165.0 -0.13
CC059/TauUncJ m 2111.0 1030.0   2   728.0 0.4877 1383.0, 2839.0 4.14
CC060/UncJ m 49.0 0.0   1   0.0 0.0 49.0, 49.0 -0.4
CC061/GeniUncJ f 284.0 0.0   1   0.0 0.0 284.0, 284.0 1.26
CC061/GeniUncJ m 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.41
CC078/TauUncJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.98
CC079/TauUncJ f 26.0 22.627   2   16.0 0.8703 10.0, 42.0 -0.8
WSB/EiJ f 62.5 67.18   2   47.5 1.0748 15.0, 110.0 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ f 137.0 232.7941623491 636.2938204313 -362.2938204313
CC011/UncJ m 128.5 232.7941623491 627.7938204313 -370.7938204313
CC013/GeniUncJ f 365.5 232.7941623491 864.7938204313 -133.7938204313
CC013/GeniUncJ m 222.0 232.7941623491 721.2938204313 -277.2938204313
CC018/UncJ f 168.5 232.7941623491 667.7938204313 -330.7938204313
CC018/UncJ m 77.25 164.6103308177 430.3040462315 -275.8040462315
CC019/TauUncJ f 245.3333333333 190.075637618 653.0050305938 -162.3383639271
CC019/TauUncJ m 260.5 232.7941623491 759.7938204313 -238.7938204313
CC059/TauUncJ f 110.0 190.075637618 517.6716972605 -297.6716972605
CC059/TauUncJ m 2111.0 232.7941623491 2610.2938204313 1611.7061795687


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ both 132.75 164.6103308177 485.8040462315 -220.3040462315
CC013/GeniUncJ both 293.75 164.6103308177 646.8040462315 -59.3040462315
CC018/UncJ both 122.875 142.5567282135 428.6287729454 -182.8787729454
CC019/TauUncJ both 252.9166666667 150.2679856454 575.2094418991 -69.3761085658
CC059/TauUncJ both 1110.5 150.2679856454 1432.7927752324 788.2072247676




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA