Project measure / variable:   CSNA03   extinction_inactive_cc_s7

ID, description, units MPD:110415   extinction_inactive_cc_s7   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 7  
cocaine study
Data set, strains CSNA03   CC w/par   43 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested36 strains33 strains
Mean of the strain means111.4   n 122.0   n
Median of the strain means84.0   n 41.0   n
SD of the strain means± 105.0 ± 293.3
Coefficient of variation (CV)0.9424 2.4037
Min–max range of strain means3.0   –   472.7   n 2.5   –   1666.0   n
Mean sample size per strain2.9   mice 3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 22237.3965 22237.3965 1.8626 0.1749
strain 12 3303179.6233 275264.9686 23.0561 < 0.0001
sex:strain 12 2464278.2921 205356.5243 17.2006 < 0.0001
Residuals 121 1444610.484 11938.9296


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 15.429 15.799   7 5.9716 1.024 1.0, 46.0 -0.91
A/J m 49.429 84.06   7 31.771 1.7006 -0.25
C57BL/6J f 30.636 40.532   11 12.221 1.323 5.0, 127.0 -0.77
C57BL/6J m 5.7273 6.7096   11 2.023 1.1715 -0.4
CAST/EiJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 -0.65
CAST/EiJ m 21.5 28.991   2   20.5 1.3484 1.0, 42.0 -0.34
CC001/UncJ m 179.5 157.7   2   111.5 0.8785 68.0, 291.0 0.2
CC002/UncJ f 472.7 364.9   3 210.7 0.772 118.0, 847.0 3.44
CC003/UncJ f 203.0 0.0   1   0.0 0.0 203.0, 203.0 0.87
CC003/UncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.41
CC004/TauUncJ f 129.1 112.8   8 39.89 0.8738 9.0, 336.0 0.17
CC004/TauUncJ m 140.4 130.4   14 34.864 0.9294 10.0, 400.0 0.06
CC005/TauUncJ f 55.0 0.0   1   0.0 0.0 55.0, 55.0 -0.54
CC006/TauUncJ f 142.0 0.0   1   0.0 0.0 142.0, 142.0 0.29
CC006/TauUncJ m 128.0 0.0   1   0.0 0.0 128.0, 128.0 0.02
CC007/UncJ f 35.0 0.0   1   0.0 0.0 35.0, 35.0 -0.73
CC007/UncJ m 27.5 21.92   2   15.5 0.7971 12.0, 43.0 -0.32
CC008/GeniUncJ m 28.5 30.406   2   21.5 1.0669 7.0, 50.0 -0.32
CC009/UncJ f 92.0 0.0   1   0.0 0.0 92.0, 92.0 -0.19
CC011/UncJ f 158.5 50.2   2   35.5 0.3167 123.0, 194.0 0.45
CC011/UncJ m 73.0 0.0   1   0.0 0.0 73.0, 73.0 -0.17
CC012/GeniUncJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.02
CC012/GeniUncJ m 64.0 0.0   1   0.0 0.0 64.0, 64.0 -0.2
CC013/GeniUncJ f 353.5 126.6   2   89.5 0.3581 264.0, 443.0 2.3
CC013/GeniUncJ m 182.0 179.6   2   127.0 0.9868 55.0, 309.0 0.2
CC016/GeniUncJ f 116.0 0.0   1   0.0 0.0 116.0, 116.0 0.04
CC018/UncJ f 232.0 225.0   3 129.9 0.9699 8.0, 458.0 1.15
CC018/UncJ m 76.2 22.961   5 10.268 0.3013 43.0, 107.0 -0.16
CC019/TauUncJ f 150.2 154.0   4 77.0 1.0249 20.0, 344.0 0.37
CC019/TauUncJ m 149.5 187.4   2   132.5 1.2534 17.0, 282.0 0.09
CC023/GeniUncJ f 53.0 0.0   1   0.0 0.0 53.0, 53.0 -0.56
CC023/GeniUncJ m 164.0 0.0   1   0.0 0.0 164.0, 164.0 0.14
CC024/GeniUncJ f 125.0 0.0   1   0.0 0.0 125.0, 125.0 0.13
CC025/GeniUncJ f 293.0 0.0   1   0.0 0.0 293.0, 293.0 1.73
CC025/GeniUncJ m 232.0 0.0   1   0.0 0.0 232.0, 232.0 0.37
CC026/GeniUncJ f 14.2 12.795   5 5.7219 0.901 4.0, 31.0 -0.93
CC026/GeniUncJ m 6.3333 9.2376   3 5.3333 1.4586 1.0, 17.0 -0.39
CC027/GeniUncJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 -0.65
CC028/GeniUncJ f 167.3 134.2   3 77.47 0.8019 26.0, 293.0 0.53
CC028/GeniUncJ m 40.0 0.0   1   0.0 0.0 40.0, 40.0 -0.28
CC030/GeniUncJ f 90.0 62.23   2   44.0 0.6914 46.0, 134.0 -0.2
CC032/GeniUncJ f 52.0 0.0   1   0.0 0.0 52.0, 52.0 -0.57
CC032/GeniUncJ m 47.0 24.042   2   17.0 0.5115 30.0, 64.0 -0.26
CC033/GeniUncJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.39
CC036/UncJ f 174.7 186.6   3 107.7 1.068 62.0, 390.0 0.6
CC036/UncJ m 482.0 0.0   1   0.0 0.0 482.0, 482.0 1.23
CC040/TauUncJ m 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.4
CC041/TauUncJ f 232.0 326.7   2   231.0 1.4081 1.0, 463.0 1.15
CC041/TauUncJ m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.41
CC044/UncJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -1.03
CC044/UncJ m 32.0 0.0   1   0.0 0.0 32.0, 32.0 -0.31
CC051/TauUncJ m 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.38
CC057/UncJ f 34.0 0.0   1   0.0 0.0 34.0, 34.0 -0.74
CC059/TauUncJ f 139.0 110.3   2   78.0 0.7936 61.0, 217.0 0.26
CC059/TauUncJ m 1666.0 789.8   2   558.5 0.474 1108.0, 2225.0 5.26
CC060/UncJ m 51.0 0.0   1   0.0 0.0 51.0, 51.0 -0.24
CC061/GeniUncJ m 41.0 0.0   1   0.0 0.0 41.0, 41.0 -0.28
CC078/TauUncJ f 112.0 0.0   1   0.0 0.0 112.0, 112.0 0.01
CC078/TauUncJ m 41.0 0.0   1   0.0 0.0 41.0, 41.0 -0.28
CC079/TauUncJ f 42.5 41.719   2   29.5 0.9816 13.0, 72.0 -0.66
CC084/TauJ f 78.0 0.0   1   0.0 0.0 78.0, 78.0 -0.32
NOD/ShiLtJ f 59.78 82.61   9 27.538 1.382 -0.49
NOD/ShiLtJ m 14.333 13.201   6 5.3893 0.921 1.0, 37.0 -0.37
NZO/HlLtJ f 9.8 8.3772   10 2.6491 0.8548 -0.97
NZO/HlLtJ m 10.6 10.362   10 3.2769 0.9776 2.0, 35.0 -0.38
PWK/PhJ f 16.167 10.147   6 4.1426 0.6277 6.0, 33.0 -0.91
PWK/PhJ m 21.833 30.116   6 12.295 1.3794 2.0, 82.0 -0.34
WSB/EiJ f 41.667 63.71   3 36.78 1.5289 -0.66
WSB/EiJ m 23.0 21.342   5 9.5446 0.9279 5.0, 55.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 15.4285714286 41.2984427586 97.1897318499 -66.3325889928
A/J m 49.4285714286 41.2984427586 131.1897318499 -32.3325889928
C57BL/6J f 30.6363636364 32.9447604056 95.8592064517 -34.586479179
C57BL/6J m 5.7272727273 32.9447604056 70.9501155427 -59.4955700881
CC004/TauUncJ f 129.125 38.6311558525 205.6055624604 52.6444375396
CC004/TauUncJ m 140.3571428571 29.202408927 198.1710138288 82.5432718855
CC013/GeniUncJ f 353.5 77.262311705 506.4611249209 200.5388750791
CC013/GeniUncJ m 182.0 77.262311705 334.9611249209 29.0388750791
CC018/UncJ f 232.0 63.0844133417 356.8922355128 107.1077644872
CC018/UncJ m 76.2 48.8649764555 172.9411096423 -20.5411096423
CC019/TauUncJ f 150.25 54.6327045367 258.4098486895 42.0901513105
CC019/TauUncJ m 149.5 77.262311705 302.4611249209 -3.4611249209
CC026/GeniUncJ f 14.2 48.8649764555 110.9411096423 -82.5411096423
CC026/GeniUncJ m 6.3333333333 63.0844133417 131.2255688461 -118.5589021794
CC041/TauUncJ f 232.0 77.262311705 384.9611249209 79.0388750791
CC041/TauUncJ m 2.5 77.262311705 155.4611249209 -150.4611249209
CC059/TauUncJ f 139.0 77.262311705 291.9611249209 -13.9611249209
CC059/TauUncJ m 1666.5 77.262311705 1819.4611249209 1513.5388750791
NOD/ShiLtJ f 59.7777777778 36.4218030245 131.8843435708 -12.3287880152
NOD/ShiLtJ m 14.3333333333 44.6074164611 102.645479982 -73.9788133153
NZO/HlLtJ f 9.8 34.5527562142 78.2062946476 -58.6062946476
NZO/HlLtJ m 10.6 34.5527562142 79.0062946476 -57.8062946476
PWK/PhJ f 16.1666666667 44.6074164611 104.4788133153 -72.145479982
PWK/PhJ m 21.8333333333 44.6074164611 110.145479982 -66.4788133153
WSB/EiJ f 41.6666666667 63.0844133417 166.5589021794 -83.2255688461
WSB/EiJ m 23.0 48.8649764555 119.7411096423 -73.7411096423


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 32.4285714286 29.202408927 90.2424424002 -25.385299543
C57BL/6J both 18.1818181818 23.2954634873 64.3013326248 -27.9376962612
CC004/TauUncJ both 134.7410714286 24.2133583464 182.6778008513 86.8043420059
CC013/GeniUncJ both 267.75 54.6327045367 375.9098486895 159.5901513105
CC018/UncJ both 154.1 39.898086203 233.0887852581 75.1112147419
CC019/TauUncJ both 149.875 47.3133100063 243.5441766346 56.2058233654
CC026/GeniUncJ both 10.2666666667 39.898086203 89.2554519248 -68.7221185914
CC041/TauUncJ both 117.25 54.6327045367 225.4098486895 9.0901513105
CC059/TauUncJ both 902.75 54.6327045367 1010.9098486895 794.5901513105
NOD/ShiLtJ both 37.0555555556 28.7939635118 94.0608010952 -19.9496899841
NZO/HlLtJ both 10.2 24.4324882278 58.5705548212 -38.1705548212
PWK/PhJ both 19.0 31.5422066708 81.4461177564 -43.4461177564
WSB/EiJ both 32.3333333333 39.898086203 111.3221185914 -46.6554519248




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA