Project measure / variable:   CSNA03   extinction_inactive_cc_s6

ID, description, units MPD:110414   extinction_inactive_cc_s6   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 6  
cocaine study
Data set, strains CSNA03   CC w/par   45 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested39 strains37 strains
Mean of the strain means102.4   n 123.6   n
Median of the strain means73.0   n 29.5   n
SD of the strain means± 117.1 ± 270.0
Coefficient of variation (CV)1.144 2.1849
Min–max range of strain means1.0   –   669.0   n 0.0   –   1436.0   n
Mean sample size per strain2.7   mice 3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 36647.2456 36647.2456 2.2458 0.1364
strain 14 2543768.6183 181697.7584 11.1346 < 0.0001
sex:strain 14 1704444.5207 121746.0372 7.4607 < 0.0001
Residuals 130 2121379.3591 16318.3028


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 10.571 14.022   7 5.2999 1.3264 -0.78
A/J m 85.86 190.3   7 71.94 2.2169 -0.14
C57BL/6J f 49.2 98.88   10 31.268 2.0097 2.0, 324.0 -0.45
C57BL/6J m 9.9091 10.368   11 3.126 1.0463 -0.42
CAST/EiJ f 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.48
CAST/EiJ m 29.5 27.577   2   19.5 0.9348 10.0, 49.0 -0.35
CC001/UncJ f 19.0 26.058   3 15.044 1.3715 2.0, 49.0 -0.71
CC001/UncJ m 120.2 100.4   4 50.22 0.8353 22.0, 242.0 -0.01
CC002/UncJ f 669.0 1029.0   3 593.9 1.5376 19.0, 1855.0 4.84
CC003/UncJ f 61.0 0.0   1   0.0 0.0 61.0, 61.0 -0.35
CC003/UncJ m 5.3333 0.57735   3 0.33333 0.1083 5.0, 6.0 -0.44
CC004/TauUncJ f 110.5 93.49   8 33.055 0.8461 5.0, 275.0 0.07
CC004/TauUncJ m 134.2 192.8   16 48.191 1.4359 11.0, 765.0 0.04
CC005/TauUncJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.73
CC005/TauUncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.45
CC006/TauUncJ f 78.0 0.0   1   0.0 0.0 78.0, 78.0 -0.21
CC006/TauUncJ m 130.0 0.0   1   0.0 0.0 130.0, 130.0 0.02
CC007/UncJ f 96.0 0.0   1   0.0 0.0 96.0, 96.0 -0.05
CC007/UncJ m 26.0 32.527   2   23.0 1.251 3.0, 49.0 -0.36
CC008/GeniUncJ m 24.5 33.234   2   23.5 1.3565 1.0, 48.0 -0.37
CC009/UncJ f 140.0 0.0   1   0.0 0.0 140.0, 140.0 0.32
CC009/UncJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
CC011/UncJ f 183.0 56.57   2   40.0 0.3091 143.0, 223.0 0.69
CC011/UncJ m 125.0 86.27   2   61.0 0.6901 64.0, 186.0 0.01
CC012/GeniUncJ f 188.0 0.0   1   0.0 0.0 188.0, 188.0 0.73
CC013/GeniUncJ f 284.0 86.27   2   61.0 0.3038 223.0, 345.0 1.55
CC013/GeniUncJ m 105.3 83.39   3 48.147 0.7917 48.0, 201.0 -0.07
CC016/GeniUncJ f 111.0 0.0   1   0.0 0.0 111.0, 111.0 0.07
CC017/UncJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.45
CC018/UncJ f 79.67 69.12   3 39.905 0.8676 13.0, 151.0 -0.19
CC018/UncJ m 63.25 20.694   4 10.347 0.3272 37.0, 85.0 -0.22
CC019/TauUncJ f 160.8 177.4   4 88.68 1.1033 19.0, 420.0 0.5
CC019/TauUncJ m 99.5 126.6   2   89.5 1.2721 10.0, 189.0 -0.09
CC023/GeniUncJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.73
CC023/GeniUncJ m 67.5 95.46   2   67.5 1.4142 -0.21
CC024/GeniUncJ f 175.0 0.0   1   0.0 0.0 175.0, 175.0 0.62
CC025/GeniUncJ f 227.0 0.0   1   0.0 0.0 227.0, 227.0 1.06
CC025/GeniUncJ m 786.0 0.0   1   0.0 0.0 786.0, 786.0 2.45
CC026/GeniUncJ f 10.4 4.827   5 2.1587 0.4641 6.0, 17.0 -0.79
CC026/GeniUncJ m 6.3333 1.5275   3 0.88192 0.2412 5.0, 8.0 -0.43
CC027/GeniUncJ f 50.0 0.0   1   0.0 0.0 50.0, 50.0 -0.45
CC027/GeniUncJ m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.38
CC028/GeniUncJ f 168.3 124.4   3 71.82 0.7389 28.0, 265.0 0.56
CC028/GeniUncJ m 42.0 0.0   1   0.0 0.0 42.0, 42.0 -0.3
CC030/GeniUncJ f 55.0 24.042   2   17.0 0.4371 38.0, 72.0 -0.4
CC032/GeniUncJ f 66.0 0.0   1   0.0 0.0 66.0, 66.0 -0.31
CC032/GeniUncJ m 74.5 62.93   2   44.5 0.8447 30.0, 119.0 -0.18
CC033/GeniUncJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.44
CC035/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.87
CC035/UncJ m 7.0 9.8995   2   7.0 1.4142 -0.43
CC036/UncJ f 157.0 127.3   2   90.0 0.8107 67.0, 247.0 0.47
CC036/UncJ m 448.0 0.0   1   0.0 0.0 448.0, 448.0 1.2
CC040/TauUncJ m 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.42
CC041/TauUncJ f 162.0 229.1   2   162.0 1.4142 0.51
CC041/TauUncJ m 0.0 0.0   2   0.0 None -0.46
CC044/UncJ f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.8
CC044/UncJ m 73.0 0.0   1   0.0 0.0 73.0, 73.0 -0.19
CC051/TauUncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.45
CC057/UncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.81
CC059/TauUncJ f 168.0 65.05   2   46.0 0.3872 122.0, 214.0 0.56
CC059/TauUncJ m 1436.0 955.3   2   675.5 0.6655 760.0, 2111.0 4.86
CC060/UncJ m 111.0 0.0   1   0.0 0.0 111.0, 111.0 -0.05
CC061/GeniUncJ f 73.0 0.0   1   0.0 0.0 73.0, 73.0 -0.25
CC061/GeniUncJ m 36.0 0.0   1   0.0 0.0 36.0, 36.0 -0.32
CC078/TauUncJ f 117.0 0.0   1   0.0 0.0 117.0, 117.0 0.12
CC078/TauUncJ m 419.0 0.0   1   0.0 0.0 419.0, 419.0 1.09
CC079/TauUncJ f 38.5 26.163   2   18.5 0.6796 20.0, 57.0 -0.55
CC084/TauJ f 96.0 0.0   1   0.0 0.0 96.0, 96.0 -0.05
NOD/ShiLtJ f 35.3 58.89   10 18.624 1.6684 -0.57
NOD/ShiLtJ m 15.833 21.236   6 8.6696 1.3412 -0.4
NZO/HlLtJ f 5.1 4.3576   10 1.378 0.8544 -0.83
NZO/HlLtJ m 9.9 7.3704   10 2.3307 0.7445 -0.42
PWK/PhJ f 17.4 13.088   5 5.8532 0.7522 6.0, 39.0 -0.73
PWK/PhJ m 15.714 11.926   7 4.5077 0.759 5.0, 40.0 -0.4
WSB/EiJ f 34.333 43.097   3 24.882 1.2552 1.0, 83.0 -0.58
WSB/EiJ m 22.2 19.791   5 8.851 0.8915 1.0, 43.0 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.5714285714 48.2823581538 106.0922998717 -84.9494427288
A/J m 85.8571428571 48.2823581538 181.3780141574 -9.6637284431
C57BL/6J f 49.2 40.3959190541 129.1184947166 -30.7184947166
C57BL/6J m 9.9090909091 38.5159975763 86.1083858102 -66.290203992
CC001/UncJ f 19.0 73.7525203236 164.9105410605 -126.9105410605
CC001/UncJ m 120.25 63.8715561933 246.6122352383 -6.1122352383
CC004/TauUncJ f 110.5 45.1640105093 199.8515934229 21.1484065771
CC004/TauUncJ m 134.25 31.9357780967 197.4311176192 71.0688823808
CC011/UncJ f 183.0 90.3280210185 361.7031868458 4.2968131542
CC011/UncJ m 125.0 90.3280210185 303.7031868458 -53.7031868458
CC013/GeniUncJ f 284.0 90.3280210185 462.7031868458 105.2968131542
CC013/GeniUncJ m 105.3333333333 73.7525203236 251.2438743938 -40.5772077272
CC018/UncJ f 79.6666666667 73.7525203236 225.5772077272 -66.2438743938
CC018/UncJ m 63.25 63.8715561933 189.6122352383 -63.1122352383
CC019/TauUncJ f 160.75 63.8715561933 287.1122352383 34.3877647617
CC019/TauUncJ m 99.5 90.3280210185 278.2031868458 -79.2031868458
CC026/GeniUncJ f 10.4 57.1284565908 123.4218191127 -102.6218191127
CC026/GeniUncJ m 6.3333333333 73.7525203236 152.2438743938 -139.5772077272
CC041/TauUncJ f 162.0 90.3280210185 340.7031868458 -16.7031868458
CC041/TauUncJ m 0.0 90.3280210185 178.7031868458 -178.7031868458
CC059/TauUncJ f 168.0 90.3280210185 346.7031868458 -10.7031868458
CC059/TauUncJ m 1435.5 90.3280210185 1614.2031868458 1256.7968131542
NOD/ShiLtJ f 35.3 40.3959190541 115.2184947166 -44.6184947166
NOD/ShiLtJ m 15.8333333333 52.1509072504 119.0076663638 -87.3409996971
NZO/HlLtJ f 5.1 40.3959190541 85.0184947166 -74.8184947166
NZO/HlLtJ m 9.9 40.3959190541 89.8184947166 -70.0184947166
PWK/PhJ f 17.4 57.1284565908 130.4218191127 -95.6218191127
PWK/PhJ m 15.7142857143 48.2823581538 111.2351570145 -79.806585586
WSB/EiJ f 34.3333333333 73.7525203236 180.2438743938 -111.5772077272
WSB/EiJ m 22.2 57.1284565908 135.2218191127 -90.8218191127


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 48.2142857143 34.1407828622 115.7577415555 -19.329170127
C57BL/6J both 29.5545454545 27.9074915816 84.7661799648 -25.6570890558
CC001/UncJ both 69.625 48.7827068351 166.1357513272 -26.8857513272
CC004/TauUncJ both 122.375 27.6571951213 177.0914528977 67.6585471023
CC011/UncJ both 154.0 63.8715561933 280.3622352383 27.6377647617
CC013/GeniUncJ both 194.6666666667 58.3064868501 310.0190777613 79.314255572
CC018/UncJ both 71.4583333333 48.7827068351 167.9690846606 -25.0524179939
CC019/TauUncJ both 130.125 55.3143902427 239.5579057954 20.6920942046
CC026/GeniUncJ both 8.3666666667 46.6451894801 100.6485955424 -83.9152622091
CC041/TauUncJ both 81.0 63.8715561933 207.3622352383 -45.3622352383
CC059/TauUncJ both 801.75 63.8715561933 928.1122352383 675.3877647617
NOD/ShiLtJ both 25.5666666667 32.9831297911 90.8198443557 -39.6865110223
NZO/HlLtJ both 7.5 28.5642282954 64.0109095563 -49.0109095563
PWK/PhJ both 16.5571428571 37.3993538091 90.5472916094 -57.4330058951
WSB/EiJ both 28.2666666667 46.6451894801 120.5485955424 -64.0152622091




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA