Project measure / variable:   CSNA03   extinction_inactive_cc_s4

ID, description, units MPD:110412   extinction_inactive_cc_s4   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 4  
cocaine study
Data set, strains CSNA03   CC w/par   48 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains43 strains
Mean of the strain means67.9   n 70.65   n
Median of the strain means48.5   n 35.5   n
SD of the strain means± 94.38 ± 141.0
Coefficient of variation (CV)1.39 1.9958
Min–max range of strain means0.0   –   551.7   n 0.0   –   851.0   n
Mean sample size per strain3.0   mice 3.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 35.5782 35.5782 0.0019 0.965
strain 23 1923936.7027 83649.4219 4.5346 < 0.0001
sex:strain 23 762165.2442 33137.6193 1.7964 0.019
Residuals 167 3080646.968 18446.9878


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 13.667 23.914   6 9.7627 1.7498 -0.57
A/J m 55.0 85.55   7 32.333 1.5554 -0.11
C57BL/6J f 42.083 68.52   12 19.781 1.6283 -0.27
C57BL/6J m 8.4545 7.7893   11 2.3486 0.9213 -0.44
CAST/EiJ f 63.0 0.0   1   0.0 0.0 63.0, 63.0 -0.05
CAST/EiJ m 8.0 11.314   2   8.0 1.4142 -0.44
CC001/UncJ f 30.667 44.736   3 25.828 1.4588 -0.39
CC001/UncJ m 66.0 63.57   4 31.783 0.9631 16.0, 156.0 -0.03
CC002/UncJ f 551.7 863.8   3 498.7 1.5657 44.0, 1549.0 5.13
CC002/UncJ m 58.0 80.61   2   57.0 1.3898 1.0, 115.0 -0.09
CC003/UncJ f 61.5 82.73   2   58.5 1.3452 3.0, 120.0 -0.07
CC003/UncJ m 10.0 7.0   3 4.0415 0.7 3.0, 17.0 -0.43
CC004/TauUncJ f 108.2 118.1   8 41.744 1.0907 9.0, 378.0 0.43
CC004/TauUncJ m 115.0 144.5   18 34.062 1.2566 4.0, 588.0 0.31
CC005/TauUncJ f 60.0 0.0   1   0.0 0.0 60.0, 60.0 -0.08
CC005/TauUncJ m 8.5 0.70711   2   0.5 0.0832 8.0, 9.0 -0.44
CC006/TauUncJ f 49.5 30.406   2   21.5 0.6143 28.0, 71.0 -0.19
CC006/TauUncJ m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.42
CC007/UncJ m 21.5 14.849   2   10.5 0.6907 11.0, 32.0 -0.35
CC008/GeniUncJ m 38.5 34.648   2   24.5 0.9 14.0, 63.0 -0.23
CC009/UncJ f 54.0 45.255   2   32.0 0.8381 22.0, 86.0 -0.15
CC009/UncJ m 2.5 3.5355   2   2.5 1.4142 -0.48
CC011/UncJ f 65.67 85.93   3 49.613 1.3086 5.0, 164.0 -0.02
CC011/UncJ m 292.3 364.2   3 210.3 1.2458 59.0, 712.0 1.57
CC012/GeniUncJ f 61.0 0.0   1   0.0 0.0 61.0, 61.0 -0.07
CC012/GeniUncJ m 38.0 15.556   2   11.0 0.4094 27.0, 49.0 -0.23
CC013/GeniUncJ f 212.5 294.9   2   208.5 1.3876 4.0, 421.0 1.53
CC013/GeniUncJ m 95.33 72.46   3 41.834 0.7601 53.0, 179.0 0.17
CC016/GeniUncJ f 34.0 0.0   1   0.0 0.0 34.0, 34.0 -0.36
CC017/UncJ f 0.0 0.0   1   0.0 None -0.72
CC017/UncJ m 3.0 1.4142   2   1.0 0.4714 2.0, 4.0 -0.48
CC018/UncJ f 123.0 90.09   3 52.01 0.7324 19.0, 177.0 0.58
CC018/UncJ m 52.2 28.622   5 12.8 0.5483 8.0, 79.0 -0.13
CC019/TauUncJ f 82.6 71.92   5 32.165 0.8707 10.0, 192.0 0.16
CC019/TauUncJ m 61.5 71.42   2   50.5 1.1613 11.0, 112.0 -0.06
CC023/GeniUncJ f 26.5 4.9497   2   3.5 0.1868 23.0, 30.0 -0.44
CC023/GeniUncJ m 57.0 82.82   3 47.816 1.453 -0.1
CC024/GeniUncJ f 107.0 0.0   1   0.0 0.0 107.0, 107.0 0.41
CC026/GeniUncJ f 10.2 6.4187   5 2.8705 0.6293 4.0, 20.0 -0.61
CC026/GeniUncJ m 7.0 7.5498   3 4.3589 1.0785 -0.45
CC027/GeniUncJ f 46.0 0.0   1   0.0 0.0 46.0, 46.0 -0.23
CC027/GeniUncJ m 35.5 50.2   2   35.5 1.4142 -0.25
CC028/GeniUncJ f 89.33 64.13   3 37.024 0.7178 23.0, 151.0 0.23
CC028/GeniUncJ m 44.8 31.491   5 14.083 0.7029 11.0, 94.0 -0.18
CC029/UncJ m 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.35
CC030/GeniUncJ f 105.0 116.0   2   82.0 1.1044 23.0, 187.0 0.39
CC030/GeniUncJ m 163.0 212.1   2   150.0 1.3014 13.0, 313.0 0.65
CC032/GeniUncJ f 50.0 0.0   1   0.0 0.0 50.0, 50.0 -0.19
CC032/GeniUncJ m 38.333 22.723   3 13.119 0.5928 14.0, 59.0 -0.23
CC033/GeniUncJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.7
CC033/GeniUncJ m 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.43
CC035/UncJ f 11.5 7.7782   2   5.5 0.6764 6.0, 17.0 -0.6
CC035/UncJ m 37.5 3.5355   2   2.5 0.0943 35.0, 40.0 -0.24
CC036/UncJ f 80.33 73.21   3 42.27 0.9114 16.0, 160.0 0.13
CC036/UncJ m 325.0 0.0   1   0.0 0.0 325.0, 325.0 1.8
CC037/TauUncJ f 26.0 0.0   1   0.0 0.0 26.0, 26.0 -0.44
CC040/TauUncJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.67
CC040/TauUncJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.44
CC041/TauUncJ f 1.0 1.4142   2   1.0 1.4142 -0.71
CC041/TauUncJ m 0.0 0.0   2   0.0 None -0.5
CC043/GeniUncJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.45
CC044/UncJ f 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.49
CC044/UncJ m 42.0 0.0   1   0.0 0.0 42.0, 42.0 -0.2
CC051/TauUncJ f 10.0 1.4142   2   1.0 0.1414 9.0, 11.0 -0.61
CC051/TauUncJ m 16.0 18.735   3 10.817 1.1709 1.0, 37.0 -0.39
CC057/UncJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.65
CC059/TauUncJ f 166.2 186.5   4 93.23 1.1216 13.0, 432.0 1.04
CC059/TauUncJ m 181.5 238.3   2   168.5 1.3129 13.0, 350.0 0.79
CC060/UncJ m 58.0 0.0   1   0.0 0.0 58.0, 58.0 -0.09
CC061/GeniUncJ f 69.5 95.46   2   67.5 1.3735 2.0, 137.0 0.02
CC061/GeniUncJ m 123.0 0.0   1   0.0 0.0 123.0, 123.0 0.37
CC075/UncJ f 0.0 0.0   1   0.0 None -0.72
CC078/TauUncJ f 272.5 218.5   2   154.5 0.8018 118.0, 427.0 2.17
CC078/TauUncJ m 851.0 496.4   2   351.0 0.5833 500.0, 1202.0 5.53
CC079/TauUncJ f 48.5 53.03   2   37.5 1.0935 11.0, 86.0 -0.21
CC079/TauUncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.48
CC084/TauJ f 75.0 0.0   1   0.0 0.0 75.0, 75.0 0.08
CC084/TauJ m 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.35
NOD/ShiLtJ f 37.364 60.6   11 18.271 1.6218 -0.32
NOD/ShiLtJ m 14.0 12.309   5 5.5045 0.8792 6.0, 35.0 -0.4
NZO/HlLtJ f 10.1 11.298   10 3.5729 1.1187 3.0, 39.0 -0.61
NZO/HlLtJ m 8.1 5.4661   10 1.7285 0.6748 1.0, 20.0 -0.44
PWK/PhJ f 11.286 8.8641   7 3.3503 0.7854 2.0, 28.0 -0.6
PWK/PhJ m 14.0 12.179   7 4.6033 0.8699 2.0, 32.0 -0.4
WSB/EiJ f 17.333 28.29   3 16.333 1.6321 1.0, 50.0 -0.54
WSB/EiJ m 5.6 3.1305   5 1.4 0.559 3.0, 11.0 -0.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 13.6666666667 55.4481557134 123.1363501125 -95.8030167791
A/J m 55.0 51.3350170548 156.3492332499 -46.3492332499
C57BL/6J f 42.0833333333 39.2077669093 119.4900888322 -35.3234221655
C57BL/6J m 8.4545454545 40.9511769529 89.3032647688 -72.3941738597
CC001/UncJ f 30.6666666667 78.4155338185 185.4801776644 -124.1468443311
CC001/UncJ m 66.0 67.9098443382 200.0724333731 -68.0724333731
CC002/UncJ f 551.6666666667 78.4155338185 706.4801776644 396.8531556689
CC002/UncJ m 58.0 96.0390228817 247.6070536166 -131.6070536166
CC003/UncJ f 61.5 96.0390228817 251.1070536166 -128.1070536166
CC003/UncJ m 10.0 78.4155338185 164.8135109977 -144.8135109977
CC004/TauUncJ f 108.25 48.0195114408 203.0535268083 13.4464731917
CC004/TauUncJ m 115.0 32.0130076272 178.2023512055 51.7976487945
CC009/UncJ f 54.0 96.0390228817 243.6070536166 -135.6070536166
CC009/UncJ m 2.5 96.0390228817 192.1070536166 -187.1070536166
CC011/UncJ f 65.6666666667 78.4155338185 220.4801776644 -89.1468443311
CC011/UncJ m 292.3333333333 78.4155338185 447.1468443311 137.5198223356
CC013/GeniUncJ f 212.5 96.0390228817 402.1070536166 22.8929463834
CC013/GeniUncJ m 95.3333333333 78.4155338185 250.1468443311 -59.4801776644
CC018/UncJ f 123.0 78.4155338185 277.8135109977 -31.8135109977
CC018/UncJ m 52.2 60.7404113126 172.1180299724 -67.7180299724
CC019/TauUncJ f 82.6 60.7404113126 202.5180299724 -37.3180299724
CC019/TauUncJ m 61.5 96.0390228817 251.1070536166 -128.1070536166
CC023/GeniUncJ f 26.5 96.0390228817 216.1070536166 -163.1070536166
CC023/GeniUncJ m 57.0 78.4155338185 211.8135109977 -97.8135109977
CC026/GeniUncJ f 10.2 60.7404113126 130.1180299724 -109.7180299724
CC026/GeniUncJ m 7.0 78.4155338185 161.8135109977 -147.8135109977
CC028/GeniUncJ f 89.3333333333 78.4155338185 244.1468443311 -65.4801776644
CC028/GeniUncJ m 44.8 60.7404113126 164.7180299724 -75.1180299724
CC030/GeniUncJ f 105.0 96.0390228817 294.6070536166 -84.6070536166
CC030/GeniUncJ m 163.0 96.0390228817 352.6070536166 -26.6070536166
CC035/UncJ f 11.5 96.0390228817 201.1070536166 -178.1070536166
CC035/UncJ m 37.5 96.0390228817 227.1070536166 -152.1070536166
CC041/TauUncJ f 1.0 96.0390228817 190.6070536166 -188.6070536166
CC041/TauUncJ m 0.0 96.0390228817 189.6070536166 -189.6070536166
CC051/TauUncJ f 10.0 96.0390228817 199.6070536166 -179.6070536166
CC051/TauUncJ m 16.0 78.4155338185 170.8135109977 -138.8135109977
CC059/TauUncJ f 166.25 67.9098443382 300.3224333731 32.1775666269
CC059/TauUncJ m 181.5 96.0390228817 371.1070536166 -8.1070536166
CC078/TauUncJ f 272.5 96.0390228817 462.1070536166 82.8929463834
CC078/TauUncJ m 851.0 96.0390228817 1040.6070536166 661.3929463834
NOD/ShiLtJ f 37.3636363636 40.9511769529 118.2123556779 -43.4850829506
NOD/ShiLtJ m 14.0 60.7404113126 133.9180299724 -105.9180299724
NZO/HlLtJ f 10.1 42.9499567312 94.89485218 -74.69485218
NZO/HlLtJ m 8.1 42.9499567312 92.89485218 -76.69485218
PWK/PhJ f 11.2857142857 51.3350170548 112.6349475356 -90.0635189641
PWK/PhJ m 14.0 51.3350170548 115.3492332499 -87.3492332499
WSB/EiJ f 17.3333333333 78.4155338185 172.1468443311 -137.4801776644
WSB/EiJ m 5.6 60.7404113126 125.5180299724 -114.3180299724


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 34.3333333333 37.7815495581 108.9243493374 -40.2576826707
C57BL/6J both 25.2689393939 28.347168641 81.2339311558 -30.6960523679
CC001/UncJ both 48.3333333333 51.867000352 150.7328457565 -54.0661790899
CC002/UncJ both 304.8333333333 61.9929227011 427.2241601634 182.4425065032
CC003/UncJ both 35.75 61.9929227011 158.1408268301 -86.6408268301
CC004/TauUncJ both 111.625 28.8561351204 168.5948295004 54.6551704996
CC009/UncJ both 28.25 67.9098443382 162.3224333731 -105.8224333731
CC011/UncJ both 179.0 55.4481557134 288.4696834458 69.5303165542
CC013/GeniUncJ both 153.9166666667 61.9929227011 276.3074934968 31.5258398366
CC018/UncJ both 87.6 49.5943381609 185.5126614641 -10.3126614641
CC019/TauUncJ both 72.05 56.8174521659 184.2230456634 -40.1230456634
CC023/GeniUncJ both 41.75 61.9929227011 164.1408268301 -80.6408268301
CC026/GeniUncJ both 8.6 49.5943381609 106.5126614641 -89.3126614641
CC028/GeniUncJ both 67.0666666667 49.5943381609 164.9793281307 -30.8459947974
CC030/GeniUncJ both 134.0 67.9098443382 268.0724333731 -0.0724333731
CC035/UncJ both 24.5 67.9098443382 158.5724333731 -109.5724333731
CC041/TauUncJ both 0.5 67.9098443382 134.5724333731 -133.5724333731
CC051/TauUncJ both 13.0 61.9929227011 135.3908268301 -109.3908268301
CC059/TauUncJ both 173.875 58.8116503639 289.9851332483 57.7648667517
CC078/TauUncJ both 561.75 67.9098443382 695.8224333731 427.6775666269
NOD/ShiLtJ both 25.6818181818 36.6278461701 97.995111094 -46.6314747304
NZO/HlLtJ both 9.1 30.3702056563 69.0590149862 -50.8590149862
PWK/PhJ both 12.6428571429 36.2993386718 84.3075872419 -59.0218729562
WSB/EiJ both 11.4666666667 49.5943381609 109.3793281307 -86.4459947974




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA