Project measure / variable:   CSNA03   extinction_active_cc_s9

ID, description, units MPD:110408   extinction_active_cc_s9   extinction, active lever presses (intravenous self administration), CC   [n]  session 9  
cocaine study
Data set, strains CSNA03   CC w/par   34 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), CC session 9



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains21 strains
Mean of the strain means493.8   n 222.5   n
Median of the strain means131.0   n 87.0   n
SD of the strain means± 950.6 ± 497.3
Coefficient of variation (CV)1.9251 2.2355
Min–max range of strain means23.0   –   4024.0   n 15.0   –   2366.0   n
Mean sample size per strain1.6   mice 1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9054045.0417 9054045.0417 15.1647 0.0016
strain 4 8917691.7614 2229422.9404 3.7341 0.0286
sex:strain 4 7180998.1552 1795249.5388 3.0069 0.0552
Residuals 14 8358651.0 597046.5


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C57BL/6J f 148.0 0.0   1   0.0 0.0 148.0, 148.0 -0.36
CC001/UncJ f 28.0 0.0   1   0.0 0.0 28.0, 28.0 -0.49
CC001/UncJ m 238.5 193.0   2   136.5 0.8094 102.0, 375.0 0.03
CC002/UncJ f 4024.0 5133.0   3 2964.0 1.2757 20.0, 9811.0 3.71
CC003/UncJ f 57.0 0.0   1   0.0 0.0 57.0, 57.0 -0.46
CC004/TauUncJ f 266.0 0.0   1   0.0 0.0 266.0, 266.0 -0.24
CC004/TauUncJ m 302.4 132.8   5 59.4 0.4392 175.0, 510.0 0.16
CC005/TauUncJ f 131.0 0.0   1   0.0 0.0 131.0, 131.0 -0.38
CC006/TauUncJ f 111.0 0.0   1   0.0 0.0 111.0, 111.0 -0.4
CC006/TauUncJ m 2366.0 0.0   1   0.0 0.0 2366.0, 2366.0 4.31
CC007/UncJ f 36.0 0.0   1   0.0 0.0 36.0, 36.0 -0.48
CC007/UncJ m 82.5 92.63   2   65.5 1.1228 17.0, 148.0 -0.28
CC008/GeniUncJ m 50.0 0.0   1   0.0 0.0 50.0, 50.0 -0.35
CC009/UncJ f 116.0 0.0   1   0.0 0.0 116.0, 116.0 -0.4
CC011/UncJ f 365.0 362.0   2   256.0 0.9919 109.0, 621.0 -0.14
CC011/UncJ m 27.0 9.8995   2   7.0 0.3666 20.0, 34.0 -0.39
CC012/GeniUncJ m 175.0 0.0   1   0.0 0.0 175.0, 175.0 -0.1
CC013/GeniUncJ f 564.5 115.3   2   81.5 0.2042 483.0, 646.0 0.07
CC013/GeniUncJ m 75.0 9.8995   2   7.0 0.132 68.0, 82.0 -0.3
CC018/UncJ f 412.5 96.87   2   68.5 0.2348 344.0, 481.0 -0.09
CC018/UncJ m 173.5 62.88   4 31.439 0.3624 105.0, 256.0 -0.1
CC019/TauUncJ f 1131.0 1073.0   3 619.6 0.9489 337.0, 2352.0 0.67
CC019/TauUncJ m 40.5 16.263   2   11.5 0.4016 29.0, 52.0 -0.37
CC023/GeniUncJ f 77.0 0.0   1   0.0 0.0 77.0, 77.0 -0.44
CC023/GeniUncJ m 127.0 0.0   1   0.0 0.0 127.0, 127.0 -0.19
CC024/GeniUncJ f 108.0 0.0   1   0.0 0.0 108.0, 108.0 -0.41
CC025/GeniUncJ f 261.0 0.0   1   0.0 0.0 261.0, 261.0 -0.24
CC027/GeniUncJ f 681.0 0.0   1   0.0 0.0 681.0, 681.0 0.2
CC028/GeniUncJ f 157.3 144.9   3 83.67 0.9212 54.0, 323.0 -0.35
CC028/GeniUncJ m 40.0 0.0   1   0.0 0.0 40.0, 40.0 -0.37
CC030/GeniUncJ m 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.16
CC032/GeniUncJ f 41.0 0.0   1   0.0 0.0 41.0, 41.0 -0.48
CC036/UncJ f 104.0 80.29   3 46.357 0.7721 37.0, 193.0 -0.41
CC036/UncJ m 139.0 0.0   1   0.0 0.0 139.0, 139.0 -0.17
CC040/TauUncJ m 84.0 0.0   1   0.0 0.0 84.0, 84.0 -0.28
CC041/TauUncJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.42
CC044/UncJ f 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.5
CC044/UncJ m 106.0 0.0   1   0.0 0.0 106.0, 106.0 -0.23
CC051/TauUncJ m 87.0 0.0   1   0.0 0.0 87.0, 87.0 -0.27
CC057/UncJ f 696.0 0.0   1   0.0 0.0 696.0, 696.0 0.21
CC059/TauUncJ f 3264.0 1716.0   3 990.5 0.5256 1283.0, 4260.0 2.91
CC059/TauUncJ m 74.5 48.79   2   34.5 0.6549 40.0, 109.0 -0.3
CC060/UncJ m 63.0 0.0   1   0.0 0.0 63.0, 63.0 -0.32
CC061/GeniUncJ f 312.0 0.0   1   0.0 0.0 312.0, 312.0 -0.19
CC061/GeniUncJ m 261.0 0.0   1   0.0 0.0 261.0, 261.0 0.08
CC078/TauUncJ f 32.0 0.0   1   0.0 0.0 32.0, 32.0 -0.49
CC079/TauUncJ f 96.0 24.042   2   17.0 0.2504 79.0, 113.0 -0.42
WSB/EiJ f 89.5 24.749   2   17.5 0.2765 72.0, 107.0 -0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ f 365.0 546.3728122811 1536.8531344208 -806.8531344208
CC011/UncJ m 27.0 546.3728122811 1198.8531344208 -1144.8531344208
CC013/GeniUncJ f 564.5 546.3728122811 1736.3531344208 -607.3531344208
CC013/GeniUncJ m 75.0 546.3728122811 1246.8531344208 -1096.8531344208
CC018/UncJ f 412.5 546.3728122811 1584.3531344208 -759.3531344208
CC018/UncJ m 173.5 386.34392062 1002.1252979037 -655.1252979037
CC019/TauUncJ f 1131.0 446.1115331394 2087.814077604 174.185922396
CC019/TauUncJ m 40.5 546.3728122811 1212.3531344208 -1131.3531344208
CC059/TauUncJ f 3264.0 446.1115331394 4220.814077604 2307.185922396
CC059/TauUncJ m 74.5 546.3728122811 1246.3531344208 -1097.3531344208


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ both 196.0 386.34392062 1024.6252979037 -632.6252979037
CC013/GeniUncJ both 319.75 386.34392062 1148.3752979037 -508.8752979037
CC018/UncJ both 293.0 334.5836498546 1010.610558203 -424.610558203
CC019/TauUncJ both 585.75 352.6821337976 1342.1779456355 -170.6779456355
CC059/TauUncJ both 1669.25 352.6821337976 2425.6779456355 912.8220543645




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA