Project measure / variable:   CSNA03   extinction_active_cc_s6

ID, description, units MPD:110405   extinction_active_cc_s6   extinction, active lever presses (intravenous self administration), CC   [n]  session 6  
cocaine study
Data set, strains CSNA03   CC w/par   45 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), CC session 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested39 strains37 strains
Mean of the strain means394.3   n 132.1   n
Median of the strain means125.0   n 70.0   n
SD of the strain means± 836.9 ± 189.0
Coefficient of variation (CV)2.1227 1.4314
Min–max range of strain means9.0   –   4292.0   n 3.0   –   1021.0   n
Mean sample size per strain2.7   mice 3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 372882.001 372882.001 9.5485 0.0024
strain 14 8877148.5545 634082.0396 16.2371 < 0.0001
sex:strain 14 6797209.2938 485514.9496 12.4327 < 0.0001
Residuals 130 5076681.7506 39051.3981


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 13.714 15.671   7 5.923 1.1427 -0.45
A/J m 21.286 27.903   7 10.546 1.3109 -0.59
C57BL/6J f 170.7 250.4   10 79.18 1.4668 15.0, 813.0 -0.27
C57BL/6J m 42.182 33.34   11 10.052 0.7904 7.0, 108.0 -0.48
CAST/EiJ f 77.0 0.0   1   0.0 0.0 77.0, 77.0 -0.38
CAST/EiJ m 48.0 18.385   2   13.0 0.383 35.0, 61.0 -0.44
CC001/UncJ f 26.0 11.136   3 6.4291 0.4283 16.0, 38.0 -0.44
CC001/UncJ m 242.8 306.3   4 153.2 1.2618 9.0, 692.0 0.59
CC002/UncJ f 4292.0 6103.0   3 3524.0 1.422 25.0, 11283.0 4.66
CC003/UncJ f 26.0 0.0   1   0.0 0.0 26.0, 26.0 -0.44
CC003/UncJ m 14.667 9.0185   3 5.2068 0.6149 6.0, 24.0 -0.62
CC004/TauUncJ f 203.5 162.9   8 57.59 0.8004 25.0, 513.0 -0.23
CC004/TauUncJ m 252.2 214.5   16 53.61 0.8502 14.0, 902.0 0.64
CC005/TauUncJ f 63.0 0.0   1   0.0 0.0 63.0, 63.0 -0.4
CC005/TauUncJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.67
CC006/TauUncJ f 185.0 0.0   1   0.0 0.0 185.0, 185.0 -0.25
CC006/TauUncJ m 1021.0 0.0   1   0.0 0.0 1021.0, 1021.0 4.7
CC007/UncJ f 268.0 0.0   1   0.0 0.0 268.0, 268.0 -0.15
CC007/UncJ m 169.5 207.2   2   146.5 1.2223 23.0, 316.0 0.2
CC008/GeniUncJ m 43.5 27.577   2   19.5 0.634 24.0, 63.0 -0.47
CC009/UncJ f 278.0 0.0   1   0.0 0.0 278.0, 278.0 -0.14
CC009/UncJ m 45.0 0.0   1   0.0 0.0 45.0, 45.0 -0.46
CC011/UncJ f 87.5 43.134   2   30.5 0.493 57.0, 118.0 -0.37
CC011/UncJ m 79.5 20.506   2   14.5 0.2579 65.0, 94.0 -0.28
CC012/GeniUncJ f 96.0 0.0   1   0.0 0.0 96.0, 96.0 -0.36
CC013/GeniUncJ f 291.0 103.2   2   73.0 0.3548 218.0, 364.0 -0.12
CC013/GeniUncJ m 82.33 35.907   3 20.731 0.4361 55.0, 123.0 -0.26
CC016/GeniUncJ f 1974.0 0.0   1   0.0 0.0 1974.0, 1974.0 1.89
CC017/UncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.68
CC018/UncJ f 300.0 298.8   3 172.5 0.9961 25.0, 618.0 -0.11
CC018/UncJ m 101.0 74.94   4 37.468 0.7419 55.0, 213.0 -0.16
CC019/TauUncJ f 550.2 715.9   4 357.9 1.301 87.0, 1618.0 0.19
CC019/TauUncJ m 116.5 34.648   2   24.5 0.2974 92.0, 141.0 -0.08
CC023/GeniUncJ f 71.0 0.0   1   0.0 0.0 71.0, 71.0 -0.39
CC023/GeniUncJ m 150.0 189.5   2   134.0 1.2634 16.0, 284.0 0.09
CC024/GeniUncJ f 124.0 0.0   1   0.0 0.0 124.0, 124.0 -0.32
CC025/GeniUncJ f 190.0 0.0   1   0.0 0.0 190.0, 190.0 -0.24
CC025/GeniUncJ m 105.0 0.0   1   0.0 0.0 105.0, 105.0 -0.14
CC026/GeniUncJ f 22.0 7.9057   5 3.5355 0.3593 12.0, 33.0 -0.44
CC026/GeniUncJ m 27.333 0.57735   3 0.33333 0.0211 27.0, 28.0 -0.55
CC027/GeniUncJ f 1169.0 0.0   1   0.0 0.0 1169.0, 1169.0 0.93
CC027/GeniUncJ m 97.0 0.0   1   0.0 0.0 97.0, 97.0 -0.19
CC028/GeniUncJ f 233.7 128.4   3 74.12 0.5494 140.0, 380.0 -0.19
CC028/GeniUncJ m 40.0 0.0   1   0.0 0.0 40.0, 40.0 -0.49
CC030/GeniUncJ f 108.5 58.69   2   41.5 0.5409 67.0, 150.0 -0.34
CC032/GeniUncJ f 53.0 0.0   1   0.0 0.0 53.0, 53.0 -0.41
CC032/GeniUncJ m 332.5 335.9   2   237.5 1.0102 95.0, 570.0 1.06
CC033/GeniUncJ m 42.0 0.0   1   0.0 0.0 42.0, 42.0 -0.48
CC035/UncJ f 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.46
CC035/UncJ m 17.0 24.042   2   17.0 1.4142 -0.61
CC036/UncJ f 191.0 111.7   2   79.0 0.5849 112.0, 270.0 -0.24
CC036/UncJ m 193.0 0.0   1   0.0 0.0 193.0, 193.0 0.32
CC040/TauUncJ m 65.0 0.0   1   0.0 0.0 65.0, 65.0 -0.35
CC041/TauUncJ f 154.0 217.8   2   154.0 1.4142 -0.29
CC041/TauUncJ m 14.0 14.142   2   10.0 1.0102 4.0, 24.0 -0.62
CC044/UncJ f 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.46
CC044/UncJ m 70.0 0.0   1   0.0 0.0 70.0, 70.0 -0.33
CC051/TauUncJ m 98.0 0.0   1   0.0 0.0 98.0, 98.0 -0.18
CC057/UncJ f 391.0 0.0   1   0.0 0.0 391.0, 391.0 0.0
CC059/TauUncJ f 2778.0 1166.0   2   824.5 0.4197 1954.0, 3603.0 2.85
CC059/TauUncJ m 199.0 49.497   2   35.0 0.2487 164.0, 234.0 0.35
CC060/UncJ m 103.0 0.0   1   0.0 0.0 103.0, 103.0 -0.15
CC061/GeniUncJ f 213.0 0.0   1   0.0 0.0 213.0, 213.0 -0.22
CC061/GeniUncJ m 306.0 0.0   1   0.0 0.0 306.0, 306.0 0.92
CC078/TauUncJ f 299.0 0.0   1   0.0 0.0 299.0, 299.0 -0.11
CC078/TauUncJ m 572.0 0.0   1   0.0 0.0 572.0, 572.0 2.33
CC079/TauUncJ f 125.0 98.99   2   70.0 0.792 55.0, 195.0 -0.32
CC084/TauJ f 96.0 0.0   1   0.0 0.0 96.0, 96.0 -0.36
NOD/ShiLtJ f 77.2 105.7   10 33.419 1.3689 5.0, 320.0 -0.38
NOD/ShiLtJ m 38.0 23.264   6 9.4974 0.6122 9.0, 68.0 -0.5
NZO/HlLtJ f 17.5 18.447   10 5.8333 1.0541 -0.45
NZO/HlLtJ m 26.1 18.592   10 5.8792 0.7123 3.0, 69.0 -0.56
PWK/PhJ f 64.8 101.1   5 45.217 1.5603 1.0, 244.0 -0.39
PWK/PhJ m 52.14 36.613   7 13.838 0.7022 11.0, 96.0 -0.42
WSB/EiJ f 76.67 81.27   3 46.92 1.06 16.0, 169.0 -0.38
WSB/EiJ m 52.0 41.201   5 18.426 0.7923 3.0, 84.0 -0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 13.7142857143 74.691171865 161.4818365918 -134.0532651632
A/J m 21.2857142857 74.691171865 169.0532651632 -126.4818365918
C57BL/6J f 170.7 62.4911178344 294.331203038 47.068796962
C57BL/6J m 42.1818181818 59.5829430152 160.059545142 -75.6959087784
CC001/UncJ f 26.0 114.0926496054 251.7186623848 -199.7186623848
CC001/UncJ m 242.75 98.8071329433 438.2280957335 47.2719042665
CC004/TauUncJ f 203.5 69.8671937338 341.7238870666 65.2761129334
CC004/TauUncJ m 252.25 49.4035664717 349.9890478667 154.5109521333
CC011/UncJ f 87.5 139.7343874676 363.9477741331 -188.9477741331
CC011/UncJ m 79.5 139.7343874676 355.9477741331 -196.9477741331
CC013/GeniUncJ f 291.0 139.7343874676 567.4477741331 14.5522258669
CC013/GeniUncJ m 82.3333333333 114.0926496054 308.0519957181 -143.3853290515
CC018/UncJ f 300.0 114.0926496054 525.7186623848 74.2813376152
CC018/UncJ m 101.0 98.8071329433 296.4780957335 -94.4780957335
CC019/TauUncJ f 550.25 98.8071329433 745.7280957335 354.7719042665
CC019/TauUncJ m 116.5 139.7343874676 392.9477741331 -159.9477741331
CC026/GeniUncJ f 22.0 88.3757863693 196.8409240689 -152.8409240689
CC026/GeniUncJ m 27.3333333333 114.0926496054 253.0519957181 -198.3853290515
CC041/TauUncJ f 154.0 139.7343874676 430.4477741331 -122.4477741331
CC041/TauUncJ m 14.0 139.7343874676 290.4477741331 -262.4477741331
CC059/TauUncJ f 2778.5 139.7343874676 3054.9477741331 2502.0522258669
CC059/TauUncJ m 199.0 139.7343874676 475.4477741331 -77.4477741331
NOD/ShiLtJ f 77.2 62.4911178344 200.831203038 -46.431203038
NOD/ShiLtJ m 38.0 80.6756862195 197.6071968126 -121.6071968126
NZO/HlLtJ f 17.5 62.4911178344 141.131203038 -106.131203038
NZO/HlLtJ m 26.1 62.4911178344 149.731203038 -97.531203038
PWK/PhJ f 64.8 88.3757863693 239.6409240689 -110.0409240689
PWK/PhJ m 52.1428571429 74.691171865 199.9104080204 -95.6246937346
WSB/EiJ f 76.6666666667 114.0926496054 302.3853290515 -149.0519957181
WSB/EiJ m 52.0 88.3757863693 226.8409240689 -122.8409240689


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5 52.8146341205 121.9874372648 -86.9874372648
C57BL/6J both 106.4409090909 43.171943744 191.8514366591 21.0303815227
CC001/UncJ both 134.375 75.4651943191 283.6738617341 -14.9238617341
CC004/TauUncJ both 227.875 42.784743602 312.5194983943 143.2305016057
CC011/UncJ both 83.5 98.8071329433 278.9780957335 -111.9780957335
CC013/GeniUncJ both 186.6666666667 90.1981592591 365.1129375523 8.220395781
CC018/UncJ both 200.5 75.4651943191 349.7988617341 51.2011382659
CC019/TauUncJ both 333.375 85.569487204 502.6639967886 164.0860032114
CC026/GeniUncJ both 24.6666666667 72.1585274073 167.4236833752 -118.0903500418
CC041/TauUncJ both 84.0 98.8071329433 279.4780957335 -111.4780957335
CC059/TauUncJ both 1488.75 98.8071329433 1684.2280957335 1293.2719042665
NOD/ShiLtJ both 57.6 51.0237840501 158.5444545765 -43.3444545765
NZO/HlLtJ both 21.8 44.1878931846 109.2204620344 -65.6204620344
PWK/PhJ both 58.4714285714 57.8555329483 172.9316813031 -55.9888241603
WSB/EiJ both 64.3333333333 72.1585274073 207.0903500418 -78.4236833752




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA