Project measure / variable:   CSNA03   extinction_active_cc_s5

ID, description, units MPD:110404   extinction_active_cc_s5   extinction, active lever presses (intravenous self administration), CC   [n]  session 5  
cocaine study
Data set, strains CSNA03   CC w/par   46 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
Download Plot   
Visualization Options

CSNA03 - extinction, active lever presses (intravenous self administration), CC session 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested39 strains40 strains
Mean of the strain means317.7   n 141.6   n
Median of the strain means95.0   n 69.0   n
SD of the strain means± 682.7 ± 254.6
Coefficient of variation (CV)2.1489 1.7982
Min–max range of strain means8.0   –   3726.0   n 4.0   –   1581.0   n
Mean sample size per strain2.9   mice 3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 719.4123 719.4123 0.0236 0.8782
strain 14 1285697.7107 91835.5508 3.0081 0.0005
sex:strain 14 507281.0545 36234.361 1.1869 0.2925
Residuals 133 4060387.2827 30529.2277


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 24.429 26.476   7 10.007 1.0838 -0.43
A/J m 14.857 26.175   7 9.8933 1.7618 -0.5
C57BL/6J f 240.4 339.3   11 102.3 1.4116 8.0, 1070.0 -0.11
C57BL/6J m 48.455 37.901   11 11.428 0.7822 12.0, 139.0 -0.37
CAST/EiJ f 72.0 0.0   1   0.0 0.0 72.0, 72.0 -0.36
CAST/EiJ m 29.5 12.021   2   8.5 0.4075 21.0, 38.0 -0.44
CC001/UncJ f 31.0 15.875   3 9.1652 0.5121 19.0, 49.0 -0.42
CC001/UncJ m 354.0 528.6   4 264.3 1.4931 11.0, 1142.0 0.83
CC002/UncJ f 3726.0 5399.0   3 3117.0 1.4491 42.0, 9923.0 4.99
CC003/UncJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.44
CC003/UncJ m 20.0 23.302   3 13.454 1.1651 1.0, 46.0 -0.48
CC004/TauUncJ f 190.0 147.8   8 52.25 0.7779 27.0, 446.0 -0.19
CC004/TauUncJ m 276.9 236.4   17 57.33 0.8537 5.0, 895.0 0.53
CC005/TauUncJ f 58.0 0.0   1   0.0 0.0 58.0, 58.0 -0.38
CC005/TauUncJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.5
CC006/TauUncJ f 221.0 0.0   1   0.0 0.0 221.0, 221.0 -0.14
CC006/TauUncJ m 1581.0 0.0   1   0.0 0.0 1581.0, 1581.0 5.65
CC007/UncJ m 98.0 70.71   2   50.0 0.7215 48.0, 148.0 -0.17
CC008/GeniUncJ m 56.5 13.435   2   9.5 0.2378 47.0, 66.0 -0.33
CC009/UncJ f 147.0 0.0   1   0.0 0.0 147.0, 147.0 -0.25
CC009/UncJ m 27.0 0.0   1   0.0 0.0 27.0, 27.0 -0.45
CC011/UncJ f 171.7 141.7   3 81.83 0.8257 39.0, 321.0 -0.21
CC011/UncJ m 80.0 22.113   3 12.767 0.2764 55.0, 97.0 -0.24
CC012/GeniUncJ f 158.0 0.0   1   0.0 0.0 158.0, 158.0 -0.23
CC012/GeniUncJ m 206.0 0.0   1   0.0 0.0 206.0, 206.0 0.25
CC013/GeniUncJ f 227.0 0.0   1   0.0 0.0 227.0, 227.0 -0.13
CC013/GeniUncJ m 64.0 26.211   3 15.133 0.4095 35.0, 86.0 -0.3
CC016/GeniUncJ f 1579.0 0.0   1   0.0 0.0 1579.0, 1579.0 1.85
CC017/UncJ m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.5
CC018/UncJ f 219.7 179.3   3 103.5 0.8165 29.0, 385.0 -0.14
CC018/UncJ m 157.8 98.13   4 49.067 0.6221 85.0, 299.0 0.06
CC019/TauUncJ f 271.5 311.4   4 155.7 1.1468 63.0, 735.0 -0.07
CC019/TauUncJ m 121.5 68.59   2   48.5 0.5645 73.0, 170.0 -0.08
CC023/GeniUncJ f 32.0 7.0711   2   5.0 0.221 27.0, 37.0 -0.42
CC023/GeniUncJ m 90.0 129.4   3 74.7 1.4376 6.0, 239.0 -0.2
CC024/GeniUncJ f 55.0 0.0   1   0.0 0.0 55.0, 55.0 -0.38
CC025/GeniUncJ m 98.0 0.0   1   0.0 0.0 98.0, 98.0 -0.17
CC026/GeniUncJ f 20.8 9.7826   5 4.3749 0.4703 6.0, 30.0 -0.43
CC026/GeniUncJ m 33.333 10.693   3 6.1734 0.3208 21.0, 40.0 -0.43
CC027/GeniUncJ f 1152.0 0.0   1   0.0 0.0 1152.0, 1152.0 1.22
CC027/GeniUncJ m 138.0 0.0   1   0.0 0.0 138.0, 138.0 -0.01
CC028/GeniUncJ f 178.5 184.6   2   130.5 1.0339 48.0, 309.0 -0.2
CC028/GeniUncJ m 58.0 1.4142   2   1.0 0.0244 57.0, 59.0 -0.33
CC030/GeniUncJ f 207.0 46.669   2   33.0 0.2255 174.0, 240.0 -0.16
CC030/GeniUncJ m 141.0 0.0   1   0.0 0.0 141.0, 141.0 0.0
CC032/GeniUncJ f 72.0 0.0   1   0.0 0.0 72.0, 72.0 -0.36
CC032/GeniUncJ m 337.0 459.8   3 265.5 1.3644 6.0, 862.0 0.77
CC033/GeniUncJ m 61.0 0.0   1   0.0 0.0 61.0, 61.0 -0.32
CC035/UncJ f 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.43
CC035/UncJ m 108.0 118.8   2   84.0 1.0999 24.0, 192.0 -0.13
CC036/UncJ f 156.5 133.6   2   94.5 0.854 62.0, 251.0 -0.24
CC036/UncJ m 403.0 0.0   1   0.0 0.0 403.0, 403.0 1.03
CC037/TauUncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.45
CC040/TauUncJ m 52.0 0.0   1   0.0 0.0 52.0, 52.0 -0.35
CC041/TauUncJ f 90.5 128.0   2   90.5 1.4142 -0.33
CC041/TauUncJ m 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.54
CC043/GeniUncJ m 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.47
CC044/UncJ f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.45
CC044/UncJ m 74.0 0.0   1   0.0 0.0 74.0, 74.0 -0.27
CC051/TauUncJ f 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.44
CC051/TauUncJ m 52.0 38.105   3 22.0 0.7328 8.0, 74.0 -0.35
CC057/UncJ f 56.0 66.47   2   47.0 1.1869 9.0, 103.0 -0.38
CC059/TauUncJ f 1760.0 1505.0   4 752.7 0.8551 2.11
CC059/TauUncJ m 64.0 0.0   1   0.0 0.0 64.0, 64.0 -0.3
CC061/GeniUncJ f 326.0 0.0   1   0.0 0.0 326.0, 326.0 0.01
CC061/GeniUncJ m 250.0 0.0   1   0.0 0.0 250.0, 250.0 0.43
CC078/TauUncJ f 418.5 372.6   2   263.5 0.8904 155.0, 682.0 0.15
CC078/TauUncJ m 267.0 292.7   2   207.0 1.0964 60.0, 474.0 0.49
CC079/TauUncJ f 95.0 55.15   2   39.0 0.5806 56.0, 134.0 -0.33
CC084/TauJ f 76.0 0.0   1   0.0 0.0 76.0, 76.0 -0.35
CC084/TauJ m 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.49
NOD/ShiLtJ f 73.8 113.7   10 35.95 1.5404 2.0, 326.0 -0.36
NOD/ShiLtJ m 95.2 91.41   5 40.878 0.9602 19.0, 246.0 -0.18
NZO/HlLtJ f 22.4 16.05   10 5.0754 0.7165 -0.43
NZO/HlLtJ m 26.9 11.874   10 3.7548 0.4414 6.0, 39.0 -0.45
PWK/PhJ f 123.6 141.5   5 63.3 1.1451 33.0, 372.0 -0.28
PWK/PhJ m 81.14 80.13   7 30.286 0.9875 1.0, 237.0 -0.24
WSB/EiJ f 60.33 52.0   3 30.024 0.8619 13.0, 116.0 -0.38
WSB/EiJ m 25.4 14.993   5 6.7052 0.5903 10.0, 49.0 -0.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 24.4285714286 66.0402774171 155.0536820344 -106.1965391773
A/J m 14.8571428571 66.0402774171 145.482253463 -115.7679677487
C57BL/6J f 240.3636363636 52.681916588 344.5664266969 136.1608460304
C57BL/6J m 48.4545454545 52.681916588 152.6573357878 -55.7482448787
CC001/UncJ f 31.0 100.8781900599 230.5331523377 -168.5331523377
CC001/UncJ m 354.0 87.3630752796 526.8007788217 181.1992211783
CC004/TauUncJ f 190.0 61.7750229555 312.1886024991 67.8113975009
CC004/TauUncJ m 276.8823529412 42.3773161361 360.7030427377 193.0616631446
CC011/UncJ f 171.6666666667 100.8781900599 371.1998190044 -27.8664856711
CC011/UncJ m 80.0 100.8781900599 279.5331523377 -119.5331523377
CC018/UncJ f 219.6666666667 100.8781900599 419.1998190044 20.1335143289
CC018/UncJ m 157.75 87.3630752796 330.5507788217 -15.0507788217
CC019/TauUncJ f 271.5 87.3630752796 444.3007788217 98.6992211783
CC019/TauUncJ m 121.5 123.5500459111 365.8772049983 -122.8772049982
CC023/GeniUncJ f 32.0 123.5500459111 276.3772049983 -212.3772049983
CC023/GeniUncJ m 90.0 100.8781900599 289.5331523377 -109.5331523377
CC026/GeniUncJ f 20.8 78.1399100195 175.3577152041 -133.7577152041
CC026/GeniUncJ m 33.3333333333 100.8781900599 232.8664856711 -166.1998190044
CC028/GeniUncJ f 178.5 123.5500459111 422.8772049982 -65.8772049982
CC028/GeniUncJ m 58.0 123.5500459111 302.3772049982 -186.3772049982
CC078/TauUncJ f 418.5 123.5500459111 662.8772049982 174.1227950018
CC078/TauUncJ m 267.0 123.5500459111 511.3772049982 22.6227950017
NOD/ShiLtJ f 73.8 55.2532602561 183.0888085055 -35.4888085055
NOD/ShiLtJ m 95.2 78.1399100195 249.7577152041 -59.3577152041
NZO/HlLtJ f 22.4 55.2532602561 131.6888085055 -86.8888085055
NZO/HlLtJ m 26.9 55.2532602561 136.1888085055 -82.3888085055
PWK/PhJ f 123.6 78.1399100195 278.1577152041 -30.9577152041
PWK/PhJ m 81.1428571429 66.0402774171 211.7679677487 -49.482253463
WSB/EiJ f 60.3333333333 100.8781900599 259.8664856711 -139.1998190044
WSB/EiJ m 25.4 78.1399100195 179.9577152041 -129.1577152041


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 19.6428571429 46.697527993 112.0087586455 -72.7230443598
C57BL/6J both 144.4090909091 37.2517404653 218.0915905723 70.7265912459
CC001/UncJ both 192.5 66.7246509022 324.4787748496 60.5212251504
CC004/TauUncJ both 233.4411764706 37.4566095104 307.5288991692 159.353453772
CC011/UncJ both 125.8333333333 71.3316522651 266.9245784229 -15.2579117562
CC018/UncJ both 188.7083333333 66.7246509022 320.6871081829 56.7295584837
CC019/TauUncJ both 196.5 75.6586425449 346.1498642533 46.8501357467
CC023/GeniUncJ both 61.0 79.7512117061 218.7448075252 -96.7448075252
CC026/GeniUncJ both 27.0666666667 63.8009693649 153.2625126868 -99.1291793535
CC028/GeniUncJ both 118.25 87.3630752796 291.0507788217 -54.5507788217
CC078/TauUncJ both 342.75 87.3630752796 515.5507788217 169.9492211783
NOD/ShiLtJ both 84.5 47.8507270237 179.1468845151 -10.1468845151
NZO/HlLtJ both 24.65 39.0699550097 101.928857602 -52.628857602
PWK/PhJ both 102.3714285714 51.154578923 203.553204166 1.1896529768
WSB/EiJ both 42.8666666667 63.8009693649 169.0625126868 -83.3291793535




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA