Project measure / variable:   CSNA03   extinction_active_cc_s4

ID, description, units MPD:110403   extinction_active_cc_s4   extinction, active lever presses (intravenous self administration), CC   [n]  session 4  
cocaine study
Data set, strains CSNA03   CC w/par   48 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), CC session 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested43 strains43 strains
Mean of the strain means259.3   n 118.3   n
Median of the strain means72.0   n 63.5   n
SD of the strain means± 594.1 ± 177.0
Coefficient of variation (CV)2.2914 1.4962
Min–max range of strain means1.0   –   3257.0   n 5.0   –   960.0   n
Mean sample size per strain3.0   mice 3.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1048637.2 1048637.2 3.3398 0.0694
strain 23 22903235.2986 995792.8391 3.1715 < 0.0001
sex:strain 23 13678049.7013 594697.8131 1.894 0.0116
Residuals 167 52435330.9815 313984.0179


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 15.333 9.7502   6 3.9805 0.6359 6.0, 31.0 -0.41
A/J m 24.714 40.269   7 15.22 1.6294 -0.53
C57BL/6J f 110.1 88.96   12 25.682 0.8082 -0.25
C57BL/6J m 52.36 65.95   11 19.885 1.2595 10.0, 241.0 -0.37
CAST/EiJ f 72.0 0.0   1   0.0 0.0 72.0, 72.0 -0.32
CAST/EiJ m 22.5 2.1213   2   1.5 0.0943 21.0, 24.0 -0.54
CC001/UncJ f 40.667 19.296   3 11.141 0.4745 19.0, 56.0 -0.37
CC001/UncJ m 339.0 522.4   4 261.2 1.5411 31.0, 1121.0 1.25
CC002/UncJ f 3257.0 4573.0   3 2640.0 1.4038 29.0, 8490.0 5.05
CC002/UncJ m 154.5 200.1   2   141.5 1.2952 13.0, 296.0 0.2
CC003/UncJ f 16.5 14.849   2   10.5 0.9 6.0, 27.0 -0.41
CC003/UncJ m 7.3333 7.0946   3 4.0961 0.9674 1.0, 15.0 -0.63
CC004/TauUncJ f 210.8 156.4   8 55.3 0.7422 18.0, 441.0 -0.08
CC004/TauUncJ m 256.6 235.1   18 55.43 0.9164 38.0, 1067.0 0.78
CC005/TauUncJ f 247.0 0.0   1   0.0 0.0 247.0, 247.0 -0.02
CC005/TauUncJ m 19.5 9.1924   2   6.5 0.4714 13.0, 26.0 -0.56
CC006/TauUncJ f 175.0 134.4   2   95.0 0.7677 80.0, 270.0 -0.14
CC006/TauUncJ m 960.0 0.0   1   0.0 0.0 960.0, 960.0 4.76
CC007/UncJ m 107.0 91.92   2   65.0 0.8591 42.0, 172.0 -0.06
CC008/GeniUncJ m 65.0 15.556   2   11.0 0.2393 54.0, 76.0 -0.3
CC009/UncJ f 100.0 100.4   2   71.0 1.0041 29.0, 171.0 -0.27
CC009/UncJ m 27.5 34.648   2   24.5 1.2599 3.0, 52.0 -0.51
CC011/UncJ f 95.33 72.6   3 41.914 0.7615 25.0, 170.0 -0.28
CC011/UncJ m 65.33 33.02   3 19.064 0.5054 33.0, 99.0 -0.3
CC012/GeniUncJ f 130.0 0.0   1   0.0 0.0 130.0, 130.0 -0.22
CC012/GeniUncJ m 63.5 34.648   2   24.5 0.5456 39.0, 88.0 -0.31
CC013/GeniUncJ f 171.0 233.3   2   165.0 1.3646 6.0, 336.0 -0.15
CC013/GeniUncJ m 74.67 38.28   3 22.101 0.5127 34.0, 110.0 -0.25
CC016/GeniUncJ f 1761.0 0.0   1   0.0 0.0 1761.0, 1761.0 2.53
CC017/UncJ f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.42
CC017/UncJ m 13.0 15.556   2   11.0 1.1966 2.0, 24.0 -0.59
CC018/UncJ f 232.3 174.6   3 100.8 0.7517 35.0, 367.0 -0.05
CC018/UncJ m 157.2 76.06   5 34.014 0.4838 92.0, 289.0 0.22
CC019/TauUncJ f 296.0 425.5   5 190.3 1.4374 33.0, 1048.0 0.06
CC019/TauUncJ m 73.5 9.1924   2   6.5 0.1251 67.0, 80.0 -0.25
CC023/GeniUncJ f 41.5 28.991   2   20.5 0.6986 21.0, 62.0 -0.37
CC023/GeniUncJ m 73.67 90.59   3 52.3 1.2297 15.0, 178.0 -0.25
CC024/GeniUncJ f 68.0 0.0   1   0.0 0.0 68.0, 68.0 -0.32
CC026/GeniUncJ f 25.6 9.1815   5 4.1061 0.3587 14.0, 37.0 -0.39
CC026/GeniUncJ m 29.667 16.503   3 9.5277 0.5563 13.0, 46.0 -0.5
CC027/GeniUncJ f 1173.0 0.0   1   0.0 0.0 1173.0, 1173.0 1.54
CC027/GeniUncJ m 176.5 244.0   2   172.5 1.3822 4.0, 349.0 0.33
CC028/GeniUncJ f 175.7 148.0   3 85.47 0.8427 78.0, 346.0 -0.14
CC028/GeniUncJ m 74.8 40.837   5 18.263 0.546 17.0, 115.0 -0.25
CC029/UncJ m 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.64
CC030/GeniUncJ f 188.5 161.9   2   114.5 0.859 74.0, 303.0 -0.12
CC030/GeniUncJ m 82.5 62.93   2   44.5 0.7628 38.0, 127.0 -0.2
CC032/GeniUncJ f 54.0 0.0   1   0.0 0.0 54.0, 54.0 -0.35
CC032/GeniUncJ m 310.3 427.4   3 246.7 1.3771 28.0, 802.0 1.08
CC033/GeniUncJ f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.41
CC033/GeniUncJ m 41.0 0.0   1   0.0 0.0 41.0, 41.0 -0.44
CC035/UncJ f 31.0 32.527   2   23.0 1.0493 8.0, 54.0 -0.38
CC035/UncJ m 47.0 1.4142   2   1.0 0.0301 46.0, 48.0 -0.4
CC036/UncJ f 161.3 79.78   3 46.059 0.4945 78.0, 237.0 -0.16
CC036/UncJ m 558.0 0.0   1   0.0 0.0 558.0, 558.0 2.48
CC037/TauUncJ f 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.4
CC040/TauUncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.43
CC040/TauUncJ m 61.0 0.0   1   0.0 0.0 61.0, 61.0 -0.32
CC041/TauUncJ f 13.5 19.092   2   13.5 1.4142 -0.41
CC041/TauUncJ m 15.0 7.0711   2   5.0 0.4714 10.0, 20.0 -0.58
CC043/GeniUncJ m 22.0 0.0   1   0.0 0.0 22.0, 22.0 -0.54
CC044/UncJ f 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.41
CC044/UncJ m 26.0 0.0   1   0.0 0.0 26.0, 26.0 -0.52
CC051/TauUncJ f 21.0 14.142   2   10.0 0.6734 11.0, 31.0 -0.4
CC051/TauUncJ m 36.0 36.497   3 21.071 1.0138 12.0, 78.0 -0.46
CC057/UncJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.41
CC059/TauUncJ f 1440.0 1532.0   4 766.1 1.0644 17.0, 3485.0 1.99
CC059/TauUncJ m 78.5 6.364   2   4.5 0.0811 74.0, 83.0 -0.22
CC060/UncJ m 58.0 0.0   1   0.0 0.0 58.0, 58.0 -0.34
CC061/GeniUncJ f 140.5 169.0   2   119.5 1.2028 21.0, 260.0 -0.2
CC061/GeniUncJ m 332.0 0.0   1   0.0 0.0 332.0, 332.0 1.21
CC075/UncJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.43
CC078/TauUncJ f 169.5 38.891   2   27.5 0.2294 142.0, 197.0 -0.15
CC078/TauUncJ m 356.0 384.7   2   272.0 1.0805 84.0, 628.0 1.34
CC079/TauUncJ f 126.5 53.03   2   37.5 0.4192 89.0, 164.0 -0.22
CC079/TauUncJ m 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.61
CC084/TauJ f 49.0 0.0   1   0.0 0.0 49.0, 49.0 -0.35
CC084/TauJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.58
NOD/ShiLtJ f 106.5 161.4   11 48.658 1.516 3.0, 453.0 -0.26
NOD/ShiLtJ m 66.0 47.418   5 21.206 0.7185 19.0, 144.0 -0.3
NZO/HlLtJ f 29.1 20.915   10 6.6139 0.7187 -0.39
NZO/HlLtJ m 23.4 24.19   10 7.6495 1.0338 2.0, 83.0 -0.54
PWK/PhJ f 64.86 43.857   7 16.577 0.6762 29.0, 134.0 -0.33
PWK/PhJ m 76.71 54.35   7 20.541 0.7084 7.0, 145.0 -0.23
WSB/EiJ f 55.0 59.57   3 34.395 1.0832 12.0, 123.0 -0.34
WSB/EiJ m 28.4 29.348   5 13.125 1.0334 7.0, 73.0 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 15.3333333333 228.7589771838 466.9655381467 -436.2988714801
A/J m 24.7142857143 211.7896590802 442.8444586351 -393.4158872065
C57BL/6J f 110.0833333333 161.757024024 429.4355279591 -209.2688612924
C57BL/6J m 52.3636363636 168.9497014588 385.9161251522 -281.188852425
CC001/UncJ f 40.6666666667 323.5140480479 679.3710559182 -598.0377225849
CC001/UncJ m 339.0 280.1713840906 892.1342266005 -214.1342266005
CC002/UncJ f 3257.3333333333 323.5140480479 3896.0377225849 2618.6289440818
CC002/UncJ m 154.5 396.2221711698 936.7499250711 -627.7499250712
CC003/UncJ f 16.5 396.2221711698 798.7499250712 -765.7499250712
CC003/UncJ m 7.3333333333 323.5140480479 646.0377225849 -631.3710559182
CC004/TauUncJ f 210.75 198.1110855849 601.8749625356 -180.3749625356
CC004/TauUncJ m 256.6111111111 132.0740570566 517.3610861348 -4.1388639126
CC009/UncJ f 100.0 396.2221711698 882.2499250712 -682.2499250712
CC009/UncJ m 27.5 396.2221711698 809.7499250712 -754.7499250712
CC011/UncJ f 95.3333333333 323.5140480479 734.0377225849 -543.3710559182
CC011/UncJ m 65.3333333333 323.5140480479 704.0377225849 -573.3710559182
CC013/GeniUncJ f 171.0 396.2221711698 953.2499250712 -611.2499250712
CC013/GeniUncJ m 74.6666666667 323.5140480479 713.3710559182 -564.0377225849
CC018/UncJ f 232.3333333333 323.5140480479 871.0377225849 -406.3710559182
CC018/UncJ m 157.2 250.5929040707 651.9382925442 -337.5382925442
CC019/TauUncJ f 296.0 250.5929040707 790.7382925442 -198.7382925442
CC019/TauUncJ m 73.5 396.2221711698 855.7499250712 -708.7499250712
CC023/GeniUncJ f 41.5 396.2221711698 823.7499250712 -740.7499250712
CC023/GeniUncJ m 73.6666666667 323.5140480479 712.3710559182 -565.0377225849
CC026/GeniUncJ f 25.6 250.5929040707 520.3382925442 -469.1382925442
CC026/GeniUncJ m 29.6666666667 323.5140480479 668.3710559182 -609.0377225849
CC028/GeniUncJ f 175.6666666667 323.5140480479 814.3710559182 -463.0377225849
CC028/GeniUncJ m 74.8 250.5929040707 569.5382925442 -419.9382925442
CC030/GeniUncJ f 188.5 396.2221711698 970.7499250712 -593.7499250712
CC030/GeniUncJ m 82.5 396.2221711698 864.7499250712 -699.7499250712
CC035/UncJ f 31.0 396.2221711698 813.2499250712 -751.2499250712
CC035/UncJ m 47.0 396.2221711698 829.2499250712 -735.2499250712
CC041/TauUncJ f 13.5 396.2221711698 795.7499250712 -768.7499250712
CC041/TauUncJ m 15.0 396.2221711698 797.2499250712 -767.2499250712
CC051/TauUncJ f 21.0 396.2221711698 803.2499250712 -761.2499250712
CC051/TauUncJ m 36.0 323.5140480479 674.7043892516 -602.7043892516
CC059/TauUncJ f 1439.5 280.1713840906 1992.6342266005 886.3657733995
CC059/TauUncJ m 78.5 396.2221711698 860.7499250712 -703.7499250712
CC078/TauUncJ f 169.5 396.2221711698 951.7499250712 -612.7499250712
CC078/TauUncJ m 356.0 396.2221711698 1138.2499250712 -426.2499250712
NOD/ShiLtJ f 106.4545454545 168.9497014588 440.0070342431 -227.097943334
NOD/ShiLtJ m 66.0 250.5929040707 560.7382925442 -428.7382925442
NZO/HlLtJ f 29.1 177.1959417857 378.9328015706 -320.7328015706
NZO/HlLtJ m 23.4 177.1959417857 373.2328015706 -326.4328015706
PWK/PhJ f 64.8571428571 211.7896590802 482.987315778 -353.2730300637
PWK/PhJ m 76.7142857143 211.7896590802 494.8444586351 -341.4158872066
WSB/EiJ f 55.0 323.5140480479 693.7043892516 -583.7043892516
WSB/EiJ m 28.4 250.5929040707 523.1382925442 -466.3382925442


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 20.0238095238 155.8729685798 327.7592843766 -287.7116653289
C57BL/6J both 81.2234848485 116.9501351475 312.1147400907 -149.6677703938
CC001/UncJ both 189.8333333333 213.9844291926 612.2965771446 -232.6299104779
CC002/UncJ both 1705.9166666667 255.7603117231 2210.8568220621 1200.9765112712
CC003/UncJ both 11.9166666667 255.7603117231 516.8568220621 -493.0234887288
CC004/TauUncJ both 233.6805555556 119.049946219 468.7174068115 -1.3562957004
CC009/UncJ both 63.75 280.1713840906 616.8842266005 -489.3842266005
CC011/UncJ both 80.3333333333 228.7589771838 531.9655381467 -371.2988714801
CC013/GeniUncJ both 122.8333333333 255.7603117231 627.7734887288 -382.1068220621
CC018/UncJ both 194.7666666667 204.6082493785 598.718790983 -209.1854576497
CC019/TauUncJ both 184.75 234.4081976474 647.5352967045 -278.0352967045
CC023/GeniUncJ both 57.5833333333 255.7603117231 562.5234887288 -447.3568220621
CC026/GeniUncJ both 27.6333333333 204.6082493785 431.5854576497 -376.318790983
CC028/GeniUncJ both 125.2333333333 204.6082493785 529.1854576497 -278.718790983
CC030/GeniUncJ both 135.5 280.1713840906 688.6342266005 -417.6342266005
CC035/UncJ both 39.0 280.1713840906 592.1342266005 -514.1342266005
CC041/TauUncJ both 14.25 280.1713840906 567.3842266005 -538.8842266005
CC051/TauUncJ both 28.5 255.7603117231 533.4401553954 -476.4401553954
CC059/TauUncJ both 759.0 242.6355360359 1238.0282919387 279.9717080613
CC078/TauUncJ both 262.75 280.1713840906 815.8842266005 -290.3842266005
NOD/ShiLtJ both 86.2272727273 151.113206896 384.5656883255 -212.1111428709
NZO/HlLtJ both 26.25 125.2964520354 273.6191462721 -221.1191462721
PWK/PhJ both 70.7857142857 149.7579041208 366.4483949767 -224.8769664053
WSB/EiJ both 41.7 204.6082493785 445.6521243163 -362.2521243163




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA