Project measure / variable:   CSNA03   reinstatement_inf_do_s2

ID, description, units MPD:110296   reinstatement_inf_do_s2   reinstatement, number of infusions (intravenous self administration), DO   [n]  session 2  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means54.1   n 42.618   n
Median of the strain means53.58   n 42.09   n
SD of the strain means± 21.381 ± 8.5116
Coefficient of variation (CV)0.3952 0.1997
Min–max range of strain means28.182   –   92.0   n 31.3   –   57.5   n
Mean sample size per strain43.2   mice 41.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8793.4337 8793.4337 6.1111 0.0137
strain 6 14762.698 2460.4497 1.7099 0.116
sex:strain 6 5923.036 987.1727 0.686 0.661
Residuals 659 948261.0849 1438.9394


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 40.0 39.598   9 13.199 0.9899 1.0, 106.0 -0.66
A/J m 46.714 43.809   7 16.558 0.9378 0.48
C57BL/6J f 74.0 37.092   12 10.708 0.5012 14.0, 132.0 0.93
C57BL/6J m 40.385 29.89   13 8.29 0.7401 5.0, 121.0 -0.26
CAST/EiJ f 92.0 0.0   1   0.0 0.0 92.0, 92.0 1.77
CAST/EiJ m 40.5 40.305   2   28.5 0.9952 12.0, 69.0 -0.25
J:DO f 51.16 39.067   293 2.2823 0.7637 -0.14
J:DO m 43.68 38.788   281 2.3139 0.888 0.12
NOD/ShiLtJ f 28.182 32.034   11 9.6586 1.1367 2.0, 104.0 -1.21
NOD/ShiLtJ m 32.667 16.621   6 6.7856 0.5088 10.0, 53.0 -1.17
NZO/HlLtJ f 32.6 25.295   10 7.9989 0.7759 -1.01
NZO/HlLtJ m 31.3 15.945   10 5.0422 0.5094 6.0, 62.0 -1.33
PWK/PhJ f 58.86 25.635   7 9.689 0.4355 34.0, 88.0 0.22
PWK/PhJ m 57.5 20.695   6 8.4489 0.3599 23.0, 85.0 1.75
WSB/EiJ f 56.0 42.438   3 24.502 0.7578 7.0, 81.0 0.09
WSB/EiJ m 48.2 22.61   5 10.111 0.4691 14.0, 70.0 0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 40.0 12.6444517071 64.828269798 15.171730202
A/J m 46.7142857143 14.3374605779 74.866897444 18.5616739845
C57BL/6J f 74.0 10.9504163953 95.5019123771 52.4980876229
C57BL/6J m 40.3846153846 10.5208197646 61.0429845779 19.7262461913
J:DO f 51.156996587 2.2160902684 55.5084456142 46.8055475598
J:DO m 43.6797153025 2.2629142477 48.1231065046 39.2363241004
NOD/ShiLtJ f 28.1818181818 11.437336907 50.6398332128 5.7238031508
NOD/ShiLtJ m 32.6666666667 15.4862273798 63.0749627673 2.2583705661
NZO/HlLtJ f 32.6 11.9955801475 56.1541648768 9.0458351232
NZO/HlLtJ m 31.3 11.9955801475 54.8541648768 7.7458351232
PWK/PhJ f 58.8571428571 14.3374605779 87.0097545869 30.7045311274
PWK/PhJ m 57.5 15.4862273798 87.9082961006 27.0917038994
WSB/EiJ f 56.0 21.9008327905 99.0038247541 12.9961752459
WSB/EiJ m 48.2 16.9643121332 81.5106194192 14.8893805808


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 43.3571428571 9.5583070519 62.125550677 24.5887350373
C57BL/6J both 57.1923076923 7.592747654 72.1012014608 42.2834139238
J:DO both 47.4183559448 1.5836537635 50.5279714359 44.3087404536
NOD/ShiLtJ both 30.4242424242 9.6259533811 49.3254785668 11.5230062816
NZO/HlLtJ both 31.95 8.4821560666 48.6053097096 15.2946902904
PWK/PhJ both 58.1785714286 10.5520852712 78.8983326419 37.4588102153
WSB/EiJ both 52.1 13.8513028545 79.2980068643 24.9019931357




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA