Project measure / variable:   CSNA03   reinstatement_inactive_do_s1

ID, description, units MPD:110292   reinstatement_inactive_do_s1   reinstatement, inactive lever presses (intravenous self administration), DO   [n]  session 1  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means41.231   n 43.807   n
Median of the strain means36.5   n 25.65   n
SD of the strain means± 29.281 ± 44.52
Coefficient of variation (CV)0.7102 1.0163
Min–max range of strain means10.222   –   89.0   n 10.846   –   129.6   n
Mean sample size per strain43.5   mice 41.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 46250.4133 46250.4133 0.5161 0.4728
strain 6 316317.6159 52719.6026 0.5883 0.7398
sex:strain 6 64494.8563 10749.1427 0.12 0.994
Residuals 661 59232690.2997 89610.7266


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 10.222 8.0743   9 2.6914 0.7899 -1.06
A/J m 129.6 307.0   7 116.0 2.3691 1.93
C57BL/6J f 42.5 46.615   12 13.457 1.0968 0.04
C57BL/6J m 10.846 9.856   13 2.7336 0.9087 -0.74
CAST/EiJ f 89.0 0.0   1   0.0 0.0 89.0, 89.0 1.63
CAST/EiJ m 32.0 39.598   2   28.0 1.2374 4.0, 60.0 -0.27
J:DO f 79.81 248.6   295 14.474 3.1148 1.32
J:DO m 97.61 380.0   281 22.67 3.8933 1.21
NOD/ShiLtJ f 34.0 48.924   11 14.751 1.439 -0.25
NOD/ShiLtJ m 15.5 13.308   6 5.4329 0.8586 2.0, 37.0 -0.64
NZO/HlLtJ f 10.6 7.8627   10 2.4864 0.7418 1.0, 22.0 -1.05
NZO/HlLtJ m 13.6 12.501   10 3.9531 0.9192 3.0, 37.0 -0.68
PWK/PhJ f 24.714 12.566   7 4.7495 0.5085 11.0, 47.0 -0.56
PWK/PhJ m 22.5 11.327   6 4.6242 0.5034 6.0, 37.0 -0.48
WSB/EiJ f 39.0 45.211   3 26.102 1.1592 1.0, 89.0 -0.08
WSB/EiJ m 28.8 30.327   5 13.562 1.053 3.0, 77.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.2222222222 99.7835026589 206.1530534379 -185.7086089935
A/J m 129.5714285714 113.1438569924 351.7361086715 -92.5932515287
C57BL/6J f 42.5 86.4150481812 212.1810772174 -127.1810772174
C57BL/6J m 10.8461538462 83.0248927574 173.870459629 -152.1781519367
J:DO f 79.8101694915 17.4288604046 114.0327715773 45.5875674058
J:DO m 97.6085409253 17.8577541424 132.6733013269 62.5437805237
NOD/ShiLtJ f 34.0 90.2575741601 211.2261050923 -143.2261050923
NOD/ShiLtJ m 15.5 122.209333131 255.4652806789 -224.4652806789
NZO/HlLtJ f 10.6 94.6629423935 196.4763071475 -175.2763071475
NZO/HlLtJ m 13.6 94.6629423935 199.4763071475 -172.2763071475
PWK/PhJ f 24.7142857143 113.1438569924 246.8789658144 -197.4503943858
PWK/PhJ m 22.5 122.209333131 262.4652806789 -217.4652806789
WSB/EiJ f 39.0 172.8300963624 378.3621544348 -300.3621544348
WSB/EiJ m 28.8 133.873616987 291.6687944918 -234.0687944918


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 69.8968253968 75.429237995 218.0066121302 -78.2129613366
C57BL/6J both 26.6730769231 59.9180552286 144.3257354583 -90.9795816122
J:DO both 88.7093552084 12.4766237221 113.2079465737 64.2107638431
NOD/ShiLtJ both 24.75 75.9630679962 173.9079936322 -124.4079936322
NZO/HlLtJ both 12.1 66.9368084935 143.5343972459 -119.3343972459
PWK/PhJ both 23.6071428571 83.2716240376 187.1159201562 -139.9016344419
WSB/EiJ both 33.9 109.3073505463 248.5314719352 -180.7314719351




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA