Project measure / variable:   CSNA03   extinction_inactive_do_s7

ID, description, units MPD:110286   extinction_inactive_do_s7   extinction, inactive lever presses (intravenous self administration), DO   [n]  session 7  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means41.185   n 36.928   n
Median of the strain means36.151   n 21.666   n
SD of the strain means± 33.578 ± 47.137
Coefficient of variation (CV)0.8153 1.2765
Min–max range of strain means9.8   –   113.0   n 5.7273   –   149.0   n
Mean sample size per strain24.1   mice 21.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 44904.9016 44904.9016 0.5398 0.463
strain 6 791019.4132 131836.5689 1.5849 0.1505
sex:strain 6 47730.3775 7955.0629 0.0956 0.9968
Residuals 350 29113254.033 83180.7258


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 15.429 15.799   7 5.9716 1.024 1.0, 46.0 -0.77
A/J m 49.429 84.06   7 31.771 1.7006 0.27
C57BL/6J f 30.636 40.532   11 12.221 1.323 5.0, 127.0 -0.31
C57BL/6J m 5.7273 6.7096   11 2.023 1.1715 -0.66
CAST/EiJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 0.05
CAST/EiJ m 21.5 28.991   2   20.5 1.3484 1.0, 42.0 -0.33
J:DO f 113.0 233.6   146 19.333 2.0669 2.14
J:DO m 149.0 408.9   127 36.285 2.7435 2.38
NOD/ShiLtJ f 59.78 82.61   9 27.538 1.382 0.55
NOD/ShiLtJ m 14.333 13.201   6 5.3893 0.921 1.0, 37.0 -0.48
NZO/HlLtJ f 9.8 8.3772   10 2.6491 0.8548 -0.93
NZO/HlLtJ m 10.6 10.362   10 3.2769 0.9776 2.0, 35.0 -0.56
PWK/PhJ f 16.167 10.147   6 4.1426 0.6277 6.0, 33.0 -0.75
PWK/PhJ m 21.833 30.116   6 12.295 1.3794 2.0, 82.0 -0.32
WSB/EiJ f 41.667 63.71   3 36.78 1.5289 0.01
WSB/EiJ m 23.0 21.342   5 9.5446 0.9279 5.0, 55.0 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 15.4285714286 109.0089942609 229.8236463383 -198.9665034812
A/J m 49.4285714286 109.0089942609 263.8236463383 -164.9665034812
C57BL/6J f 30.6363636364 86.9590947768 201.6644679241 -140.3917406514
C57BL/6J m 5.7272727273 86.9590947768 176.755377015 -165.3008315605
J:DO f 113.0205479452 23.8690384953 159.9653375097 66.0757583807
J:DO m 149.0472440945 25.5923102699 199.3813042757 98.7131839133
NOD/ShiLtJ f 59.7777777778 96.1368964946 248.8564612872 -129.3009057316
NOD/ShiLtJ m 14.3333333333 117.7431709332 245.906481251 -217.2398145843
NZO/HlLtJ f 9.8 91.2034680308 189.1757890628 -169.5757890628
NZO/HlLtJ m 10.6 91.2034680308 189.9757890628 -168.7757890628
PWK/PhJ f 16.1666666667 117.7431709332 247.7398145843 -215.406481251
PWK/PhJ m 21.8333333333 117.7431709332 253.406481251 -209.7398145843
WSB/EiJ f 41.6666666667 166.5139892106 369.1605531332 -285.8272197999
WSB/EiJ m 23.0 128.9811814246 276.6756736539 -230.6756736539


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 32.4285714286 77.0809990522 184.0287827503 -119.1716398931
C57BL/6J both 18.1818181818 61.4893656025 139.1169504972 -102.7533141335
J:DO both 131.0338960198 17.4978380353 165.4480314934 96.6197605463
NOD/ShiLtJ both 37.0555555556 76.0028900257 186.5353797745 -112.4242686634
NZO/HlLtJ both 10.2 64.4905907123 137.037836827 -116.637836827
PWK/PhJ both 19.0 83.2569946053 182.7469432333 -144.7469432333
WSB/EiJ both 32.3333333333 105.3126936372 239.4586535363 -174.7919868697




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA