Project measure / variable:   CSNA03   extinction_inactive_do_s4

ID, description, units MPD:110283   extinction_inactive_do_s4   extinction, inactive lever presses (intravenous self administration), DO   [n]  session 4  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means34.975   n 23.273   n
Median of the strain means27.348   n 11.227   n
SD of the strain means± 27.481 ± 25.773
Coefficient of variation (CV)0.7857 1.1074
Min–max range of strain means10.1   –   84.97   n 5.6   –   73.03   n
Mean sample size per strain35.8   mice 31.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18189.9971 18189.9971 0.599 0.4393
strain 6 271126.0714 45187.6786 1.4881 0.18
sex:strain 6 13472.2652 2245.3775 0.0739 0.9984
Residuals 524 15912196.1737 30366.7866


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 13.667 23.914   6 9.7627 1.7498 -0.78
A/J m 55.0 85.55   7 32.333 1.5554 1.23
C57BL/6J f 42.083 68.52   12 19.781 1.6283 0.26
C57BL/6J m 8.4545 7.7893   11 2.3486 0.9213 -0.57
CAST/EiJ f 63.0 0.0   1   0.0 0.0 63.0, 63.0 1.02
CAST/EiJ m 8.0 11.314   2   8.0 1.4142 -0.59
J:DO f 84.97 208.4   236 13.567 2.453 1.82
J:DO m 73.03 163.9   208 11.367 2.2448 1.93
NOD/ShiLtJ f 37.364 60.6   11 18.271 1.6218 0.09
NOD/ShiLtJ m 14.0 12.309   5 5.5045 0.8792 6.0, 35.0 -0.36
NZO/HlLtJ f 10.1 11.298   10 3.5729 1.1187 3.0, 39.0 -0.91
NZO/HlLtJ m 8.1 5.4661   10 1.7285 0.6748 1.0, 20.0 -0.59
PWK/PhJ f 11.286 8.8641   7 3.3503 0.7854 2.0, 28.0 -0.86
PWK/PhJ m 14.0 12.179   7 4.6033 0.8699 2.0, 32.0 -0.36
WSB/EiJ f 17.333 28.29   3 16.333 1.6321 1.0, 50.0 -0.64
WSB/EiJ m 5.6 3.1305   5 1.4 0.559 3.0, 11.0 -0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 13.6666666667 71.1416270443 153.4245009154 -126.0911675821
A/J m 55.0 65.8643482481 184.3906120482 -74.3906120482
C57BL/6J f 42.0833333333 50.3047269076 140.9070456546 -56.7403789879
C57BL/6J m 8.4545454545 52.5415736614 111.6725466169 -94.7634557078
J:DO f 84.9661016949 11.343404451 107.2502369465 62.6819664433
J:DO m 73.0288461538 12.0828045711 96.7655340631 49.2921582446
NOD/ShiLtJ f 37.3636363636 52.5415736614 140.581637526 -65.8543647987
NOD/ShiLtJ m 14.0 77.9317478195 167.0970368122 -139.0970368122
NZO/HlLtJ f 10.1 55.1060673529 118.3559529095 -98.1559529095
NZO/HlLtJ m 8.1 55.1060673529 116.3559529095 -100.1559529095
PWK/PhJ f 11.2857142857 65.8643482481 140.6763263339 -118.1048977625
PWK/PhJ m 14.0 65.8643482481 143.3906120482 -115.3906120482
WSB/EiJ f 17.3333333333 100.6094538153 214.9807579758 -180.3140913091
WSB/EiJ m 5.6 77.9317478195 158.6970368122 -147.4970368122


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 34.3333333333 48.4748477787 129.5622453298 -60.8955786631
C57BL/6J both 25.2689393939 36.3702574643 96.7183653554 -46.1804865675
J:DO both 78.9974739244 8.2865401532 95.2763946258 62.718553223
NOD/ShiLtJ both 25.6818181818 46.9946121407 118.0028050221 -66.6391686584
NZO/HlLtJ both 9.1 38.9658739098 85.6485184061 -67.4485184061
PWK/PhJ both 12.6428571429 46.5731272847 104.135836344 -78.8501220583
WSB/EiJ both 11.4666666667 63.6310056404 136.469873774 -113.5365404407




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA