Project measure / variable:   CSNA03   extinction_inactive_do_s2

ID, description, units MPD:110281   extinction_inactive_do_s2   extinction, inactive lever presses (intravenous self administration), DO   [n]  session 2  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means35.189   n 25.686   n
Median of the strain means32.0   n 19.786   n
SD of the strain means± 18.123 ± 18.775
Coefficient of variation (CV)0.515 0.7309
Min–max range of strain means7.1111   –   59.31   n 7.4   –   55.83   n
Mean sample size per strain40.2   mice 38.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7507.52 7507.52 0.6102 0.435
strain 6 77483.7226 12913.9538 1.0497 0.3919
sex:strain 6 21876.3606 3646.0601 0.2964 0.9387
Residuals 611 7517151.4752 12303.0302


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 7.1111 8.8097   9 2.9366 1.2389 -1.55
A/J m 55.83 78.2   6 31.926 1.4007 1.61
C57BL/6J f 52.18 61.7   11 18.604 1.1824 2.0, 206.0 0.94
C57BL/6J m 10.333 12.766   12 3.6852 1.2354 -0.82
CAST/EiJ f 33.0 0.0   1   0.0 0.0 33.0, 33.0 -0.12
CAST/EiJ m 24.5 24.749   2   17.5 1.0102 7.0, 42.0 -0.06
J:DO f 59.31 119.5   273 7.2349 2.0155 1.33
J:DO m 53.63 116.3   258 7.2383 2.168 1.49
NOD/ShiLtJ f 51.91 84.26   11 25.405 1.6232 0.92
NOD/ShiLtJ m 18.143 26.429   7 9.9891 1.4567 -0.4
NZO/HlLtJ f 17.8 24.625   10 7.7872 1.3834 -0.96
NZO/HlLtJ m 14.222 13.236   9 4.412 0.9307 3.0, 41.0 -0.61
PWK/PhJ f 29.2 17.612   5 7.8765 0.6032 7.0, 55.0 -0.33
PWK/PhJ m 21.429 8.3038   7 3.1385 0.3875 11.0, 32.0 -0.23
WSB/EiJ f 31.0 36.77   2   26.0 1.1861 5.0, 57.0 -0.23
WSB/EiJ m 7.4 6.6558   5 2.9766 0.8994 1.0, 15.0 -0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 7.1111111111 36.9730085297 79.7207077412 -65.4984855189
A/J m 55.8333333333 45.2825025767 144.7615644198 -33.0948977531
C57BL/6J f 52.1818181818 33.4433445446 117.8596695093 -13.4960331457
C57BL/6J m 10.3333333333 32.0195646411 73.2150885735 -52.5484219068
J:DO f 59.3113553114 6.7131248183 72.4949534163 46.1277572064
J:DO m 53.6279069767 6.905516904 67.1893350796 40.0664788739
NOD/ShiLtJ f 51.9090909091 33.4433445446 117.5869422366 -13.7687604184
NOD/ShiLtJ m 18.1428571429 41.9234510535 100.4744009199 -64.1886866342
NZO/HlLtJ f 17.8 35.0756756708 86.6835116011 -51.0835116011
NZO/HlLtJ m 14.2222222222 36.9730085297 86.8318188523 -58.3873744078
PWK/PhJ f 29.2 49.6044962431 126.6159963302 -68.2159963302
PWK/PhJ m 21.4285714286 41.9234510535 103.7601152056 -60.9029723485
WSB/EiJ f 31.0 78.4315951567 185.028214469 -123.028214469
WSB/EiJ m 7.4 49.6044962431 104.8159963302 -90.0159963302


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 31.4722222222 29.2297297257 88.8751485565 -25.930704112
C57BL/6J both 31.2575757576 23.1501069875 76.7210096828 -14.2058581676
J:DO both 56.4696311441 4.8153974015 65.9263693658 47.0128929223
NOD/ShiLtJ both 35.025974026 26.8143293901 87.6854063618 -17.6334583098
NZO/HlLtJ both 16.0111111111 25.4818876042 66.053822102 -34.0315998798
PWK/PhJ both 25.3142857143 32.4737655491 89.0880252975 -38.4594538689
WSB/EiJ both 19.2 46.4007574463 110.3243205647 -71.9243205647




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA