Project measure / variable:   CSNA03   extinction_inactive_do_s1

ID, description, units MPD:110280   extinction_inactive_do_s1   extinction, inactive lever presses (intravenous self administration), DO   [n]  session 1  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means37.902   n 41.357   n
Median of the strain means33.166   n 29.416   n
SD of the strain means± 18.032 ± 39.68
Coefficient of variation (CV)0.4758 0.9595
Min–max range of strain means19.778   –   72.9   n 7.8   –   134.3   n
Mean sample size per strain40.5   mice 38.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12257.4962 12257.4962 1.3954 0.2379
strain 6 39796.1627 6632.6938 0.7551 0.6055
sex:strain 6 67846.0235 11307.6706 1.2873 0.2609
Residuals 614 5393323.5453 8783.9146


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 19.778 25.733   9 8.5777 1.3011 -1.01
A/J m 134.3 289.6   7 109.5 2.1565 2.0, 788.0 2.34
C57BL/6J f 36.333 31.827   12 9.1877 0.876 -0.09
C57BL/6J m 19.583 17.239   12 4.9764 0.8803 3.0, 57.0 -0.55
CAST/EiJ f 30.0 0.0   1   0.0 0.0 30.0, 30.0 -0.44
CAST/EiJ m 34.0 24.042   2   17.0 0.7071 17.0, 51.0 -0.19
J:DO f 54.47 101.7   274 6.1462 1.8676 0.92
J:DO m 43.529 84.97   259 5.2795 1.9519 0.05
NOD/ShiLtJ f 72.9 128.0   10 40.477 1.7558 1.94
NOD/ShiLtJ m 24.833 18.862   6 7.7003 0.7595 -0.42
NZO/HlLtJ f 20.9 19.273   10 6.0945 0.9221 2.0, 54.0 -0.94
NZO/HlLtJ m 20.667 15.091   9 5.0305 0.7302 3.0, 47.0 -0.52
PWK/PhJ f 40.333 20.106   6 8.2084 0.4985 8.0, 71.0 0.13
PWK/PhJ m 46.143 63.33   7 23.938 1.3726 9.0, 186.0 0.12
WSB/EiJ f 28.5 34.648   2   24.5 1.2157 4.0, 53.0 -0.52
WSB/EiJ m 7.8 10.918   5 4.8826 1.3997 1.0, 27.0 -0.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 19.7777777778 31.2408467818 81.1296497519 -41.5740941963
A/J m 134.2857142857 35.4237905708 203.8521981622 64.7192304092
C57BL/6J f 36.3333333333 27.0553669488 89.4656130327 -16.798946366
C57BL/6J m 19.5833333333 27.0553669488 72.7156130327 -33.548946366
J:DO f 54.4744525547 5.6619857266 65.5936589528 43.3552461567
J:DO m 43.528957529 5.8236352964 54.9656170286 32.0922980293
NOD/ShiLtJ f 72.9 29.6376695589 131.103496246 14.696503754
NOD/ShiLtJ m 24.8333333333 38.262066874 99.9737238839 -50.3070572172
NZO/HlLtJ f 20.9 29.6376695589 79.103496246 -37.303496246
NZO/HlLtJ m 20.6666666667 31.2408467818 82.0185386408 -40.6852053075
PWK/PhJ f 40.3333333333 38.262066874 115.4737238839 -34.8070572172
PWK/PhJ m 46.1428571429 35.4237905708 115.7093410193 -23.4236267336
WSB/EiJ f 28.5 66.2718438284 158.6469741342 -101.6469741342
WSB/EiJ m 7.8 41.9139942473 90.1121737686 -74.5121737686


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 77.0317460317 23.6158603805 123.4094019494 30.6540901141
C57BL/6J both 27.9583333333 19.131033437 65.5285286086 -9.611861942
J:DO both 49.0017050419 4.061182415 56.9771976823 41.0262124014
NOD/ShiLtJ both 48.8666666667 24.1990558615 96.3896223496 1.3437109838
NZO/HlLtJ both 20.7833333333 21.5312677549 63.0671930495 -21.5005263828
PWK/PhJ both 43.2380952381 26.0712039417 94.4376410638 -7.9614505876
WSB/EiJ both 18.15 39.2069515462 95.1459882507 -58.8459882507




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA