Project measure / variable:   CSNA03   extinction_active_do_s7

ID, description, units MPD:110277   extinction_active_do_s7   extinction, active lever presses (intravenous self administration), DO   [n]  session 7  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means76.35   n 56.67   n
Median of the strain means64.75   n 37.954   n
SD of the strain means± 48.104 ± 52.83
Coefficient of variation (CV)0.63 0.9322
Min–max range of strain means25.0   –   156.2   n 17.857   –   178.9   n
Mean sample size per strain24.1   mice 21.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4038.0974 4038.0974 0.041 0.8396
strain 6 967189.0523 161198.1754 1.638 0.1357
sex:strain 6 91091.5398 15181.9233 0.1543 0.9881
Residuals 350 34444745.0357 98413.5572


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 25.0 27.092   7 10.24 1.0837 -1.07
A/J m 17.857 17.563   7 6.6384 0.9836 -0.73
C57BL/6J f 139.3 174.9   11 52.75 1.2561 16.0, 530.0 1.31
C57BL/6J m 33.909 27.197   11 8.2003 0.8021 6.0, 95.0 -0.43
CAST/EiJ f 78.0 0.0   1   0.0 0.0 78.0, 78.0 0.03
CAST/EiJ m 42.0 7.0711   2   5.0 0.1684 37.0, 47.0 -0.28
J:DO f 156.2 272.1   146 22.52 1.7423 4.0, 2257.0 1.66
J:DO m 178.9 430.1   127 38.169 2.4038 1.0, 4209.0 2.31
NOD/ShiLtJ f 54.0 64.23   9 21.409 1.1894 -0.46
NOD/ShiLtJ m 31.167 19.753   6 8.064 0.6338 5.0, 53.0 -0.48
NZO/HlLtJ f 28.8 29.813   10 9.4279 1.0352 -0.99
NZO/HlLtJ m 21.9 10.115   10 3.1988 0.4619 7.0, 36.0 -0.66
PWK/PhJ f 74.5 39.889   6 16.284 0.5354 31.0, 131.0 -0.04
PWK/PhJ m 77.83 55.46   6 22.643 0.7126 28.0, 172.0 0.4
WSB/EiJ f 55.0 55.97   3 32.316 1.0177 6.0, 116.0 -0.44
WSB/EiJ m 49.8 24.773   5 11.079 0.4974 22.0, 77.0 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 25.0 118.5709897337 258.2012729631 -208.2012729631
A/J m 17.8571428571 118.5709897337 251.0584158203 -215.344130106
C57BL/6J f 139.2727272727 94.5869283901 325.3029877587 -46.7575332133
C57BL/6J m 33.9090909091 94.5869283901 219.9393513951 -152.1211695769
J:DO f 156.1849315068 25.9627706646 207.2476002273 105.1222627864
J:DO m 178.9448818898 27.8372035156 233.6941195418 124.1956442378
NOD/ShiLtJ f 54.0 104.5697838474 259.664191228 -151.664191228
NOD/ShiLtJ m 31.1666666667 128.0713064696 283.0528301021 -220.7194967688
NZO/HlLtJ f 28.8 99.2036074168 223.9101832251 -166.3101832251
NZO/HlLtJ m 21.9 99.2036074168 217.0101832251 -173.2101832251
PWK/PhJ f 74.5 128.0713064696 326.3861634354 -177.3861634354
PWK/PhJ m 77.8333333333 128.0713064696 329.7194967688 -174.0528301021
WSB/EiJ f 55.0 181.1201785601 411.2208285045 -301.2208285045
WSB/EiJ m 49.8 140.2950870451 325.727467274 -226.127467274


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 21.4285714286 83.8423508927 186.3267729221 -143.469630065
C57BL/6J both 86.5909090909 66.8830584762 218.1341677864 -44.9523496046
J:DO both 167.5649066983 19.0327044856 204.9977637905 130.1320496061
NOD/ShiLtJ both 42.5833333333 82.6696728473 205.1751526876 -120.0084860209
NZO/HlLtJ both 25.35 70.1475435226 163.313733637 -112.613733637
PWK/PhJ both 76.1666666667 90.5600892801 254.2770809189 -101.9437475856
WSB/EiJ both 52.4 114.5504588933 277.6938336133 -172.8938336133




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA