Project measure / variable:   CSNA03   extinction_active_do_s5

ID, description, units MPD:110275   extinction_active_do_s5   extinction, active lever presses (intravenous self administration), DO   [n]  session 5  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means93.53   n 59.26   n
Median of the strain means72.9   n 38.977   n
SD of the strain means± 71.41 ± 47.284
Coefficient of variation (CV)0.7634 0.798
Min–max range of strain means22.4   –   240.4   n 14.857   –   152.6   n
Mean sample size per strain30.6   mice 26.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2262.9808 2262.9808 0.0283 0.8665
strain 6 554556.6128 92426.1021 1.155 0.3295
sex:strain 6 248058.0202 41343.0034 0.5166 0.7958
Residuals 440 35211433.0932 80025.9843


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 24.429 26.476   7 10.007 1.0838 -0.97
A/J m 14.857 26.175   7 9.8933 1.7618 -0.94
C57BL/6J f 240.4 339.3   11 102.3 1.4116 8.0, 1070.0 2.06
C57BL/6J m 48.455 37.901   11 11.428 0.7822 12.0, 139.0 -0.23
CAST/EiJ f 72.0 0.0   1   0.0 0.0 72.0, 72.0 -0.3
CAST/EiJ m 29.5 12.021   2   8.5 0.4075 21.0, 38.0 -0.63
J:DO f 131.3 188.0   198 13.363 1.4324 1.0, 1238.0 0.53
J:DO m 152.6 404.2   165 31.467 2.6496 1.97
NOD/ShiLtJ f 73.8 113.7   10 35.95 1.5404 2.0, 326.0 -0.28
NOD/ShiLtJ m 95.2 91.41   5 40.878 0.9602 19.0, 246.0 0.76
NZO/HlLtJ f 22.4 16.05   10 5.0754 0.7165 -1.0
NZO/HlLtJ m 26.9 11.874   10 3.7548 0.4414 6.0, 39.0 -0.68
PWK/PhJ f 123.6 141.5   5 63.3 1.1451 33.0, 372.0 0.42
PWK/PhJ m 81.14 80.13   7 30.286 0.9875 1.0, 237.0 0.46
WSB/EiJ f 60.33 52.0   3 30.024 0.8619 13.0, 116.0 -0.46
WSB/EiJ m 25.4 14.993   5 6.7052 0.5903 10.0, 49.0 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 24.4285714286 106.921856848 234.5695939597 -185.7124511025
A/J m 14.8571428571 106.921856848 224.9981653883 -195.283879674
C57BL/6J f 240.3636363636 85.2941350977 407.9981808219 72.7290919054
C57BL/6J m 48.4545454545 85.2941350977 216.0890899128 -119.1799990037
J:DO f 131.2676767677 20.104020441 170.7795178169 91.7558357185
J:DO m 152.5515151515 22.0228509842 195.8345684139 109.2684618891
NOD/ShiLtJ f 73.8 89.4572435875 249.6165934868 -102.0165934868
NOD/ShiLtJ m 95.2 126.511647134 343.8422109992 -153.4422109992
NZO/HlLtJ f 22.4 89.4572435875 198.2165934868 -153.4165934868
NZO/HlLtJ m 26.9 89.4572435875 202.7165934868 -148.9165934868
PWK/PhJ f 123.6 126.511647134 372.2422109992 -125.0422109992
PWK/PhJ m 81.1428571429 106.921856848 291.283879674 -128.9981653883
WSB/EiJ f 60.3333333333 163.3258341504 381.3290474548 -260.6623807881
WSB/EiJ m 25.4 126.511647134 274.0422109992 -223.2422109992


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 19.6428571429 75.6051700343 168.2349991801 -128.9492848944
C57BL/6J both 144.4090909091 60.312061323 262.9446140566 25.8735677615
J:DO both 141.9095959596 14.9095405979 171.2123615407 112.6068303785
NOD/ShiLtJ both 84.5 77.4722454993 236.7616363664 -67.7616363664
NZO/HlLtJ both 24.65 63.255823567 148.9711054996 -99.6711054996
PWK/PhJ both 102.3714285714 82.8213141836 265.145964695 -60.4031075522
WSB/EiJ both 42.8666666667 103.2963273324 245.8821818219 -160.1488484885




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA