Project measure / variable:   CSNA03   extinction_active_do_s4

ID, description, units MPD:110274   extinction_active_do_s4   extinction, active lever presses (intravenous self administration), DO   [n]  session 4  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means71.44   n 51.12   n
Median of the strain means68.43   n 40.38   n
SD of the strain means± 38.177 ± 33.267
Coefficient of variation (CV)0.5344 0.6507
Min–max range of strain means15.333   –   118.6   n 22.5   –   114.9   n
Mean sample size per strain35.8   mice 31.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8855.2681 8855.2681 0.3048 0.5811
strain 6 340957.6137 56826.269 1.9561 0.0702
sex:strain 6 22641.3652 3773.5609 0.1299 0.9926
Residuals 524 15222278.1842 29050.1492


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 15.333 9.7502   6 3.9805 0.6359 6.0, 31.0 -1.47
A/J m 24.714 40.269   7 15.22 1.6294 -0.79
C57BL/6J f 110.1 88.96   12 25.682 0.8082 1.01
C57BL/6J m 52.36 65.95   11 19.885 1.2595 10.0, 241.0 0.04
CAST/EiJ f 72.0 0.0   1   0.0 0.0 72.0, 72.0 0.01
CAST/EiJ m 22.5 2.1213   2   1.5 0.0943 21.0, 24.0 -0.86
J:DO f 118.6 163.1   236 10.619 1.3752 2.0, 1017.0 1.24
J:DO m 114.9 202.8   208 14.058 1.7643 1.92
NOD/ShiLtJ f 106.5 161.4   11 48.658 1.516 3.0, 453.0 0.92
NOD/ShiLtJ m 66.0 47.418   5 21.206 0.7185 19.0, 144.0 0.45
NZO/HlLtJ f 29.1 20.915   10 6.6139 0.7187 -1.11
NZO/HlLtJ m 23.4 24.19   10 7.6495 1.0338 2.0, 83.0 -0.83
PWK/PhJ f 64.86 43.857   7 16.577 0.6762 29.0, 134.0 -0.17
PWK/PhJ m 76.71 54.35   7 20.541 0.7084 7.0, 145.0 0.77
WSB/EiJ f 55.0 59.57   3 34.395 1.0832 12.0, 123.0 -0.43
WSB/EiJ m 28.4 29.348   5 13.125 1.0334 7.0, 73.0 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 15.3333333333 69.5822645106 152.0277975191 -121.3611308524
A/J m 24.7142857143 64.4206590716 151.2687681851 -101.8401967565
C57BL/6J f 110.0833333333 49.2020910857 206.7409159097 13.4257507569
C57BL/6J m 52.3636363636 51.3899081059 153.3191887951 -48.5919160678
J:DO f 118.6186440678 11.0947669002 140.4143304738 96.8229576618
J:DO m 114.9230769231 11.8179600134 138.1394772969 91.7066765492
NOD/ShiLtJ f 106.4545454545 51.3899081059 207.410097886 5.4989930231
NOD/ShiLtJ m 66.0 76.2235517495 215.7412830412 -83.7412830412
NZO/HlLtJ f 29.1 53.8981903282 134.983076662 -76.783076662
NZO/HlLtJ m 23.4 53.8981903282 129.283076662 -82.483076662
PWK/PhJ f 64.8571428571 64.4206590716 191.411625328 -61.6973396137
PWK/PhJ m 76.7142857143 64.4206590716 203.2687681851 -49.8401967565
WSB/EiJ f 55.0 98.4041821715 248.3151651528 -138.3151651528
WSB/EiJ m 28.4 76.2235517495 178.1412830412 -121.3412830412


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 20.0238095238 47.4123213143 113.1653866692 -73.1177676215
C57BL/6J both 81.2234848485 35.5730530822 151.1068015919 11.340168105
J:DO both 116.7708604954 8.1049064067 132.6929614264 100.8487595645
NOD/ShiLtJ both 86.2272727273 45.9645311529 176.5246639044 -4.0701184499
NZO/HlLtJ both 26.25 38.1117758747 101.1206415206 -48.6206415206
PWK/PhJ both 70.7857142857 45.552284878 160.2732470304 -18.701818459
WSB/EiJ both 41.7 62.2362693896 163.9632456269 -80.5632456269




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA