Project measure / variable:   CSNA03   extinction_active_do_s2

ID, description, units MPD:110272   extinction_active_do_s2   extinction, active lever presses (intravenous self administration), DO   [n]  session 2  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means107.9   n 62.02   n
Median of the strain means111.5   n 53.91   n
SD of the strain means± 74.27 ± 33.653
Coefficient of variation (CV)0.6885 0.5426
Min–max range of strain means24.333   –   265.0   n 25.2   –   111.7   n
Mean sample size per strain40.2   mice 38.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2340.2787 2340.2787 0.1098 0.7405
strain 6 282583.4698 47097.245 2.2091 0.0406
sex:strain 6 245147.5706 40857.9284 1.9164 0.076
Residuals 611 13026527.8234 21320.0128


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 24.333 24.454   9 8.1513 1.005 4.0, 80.0 -1.12
A/J m 37.5 45.148   6 18.431 1.2039 6.0, 106.0 -0.73
C57BL/6J f 265.0 346.2   11 104.4 1.3065 5.0, 1241.0 2.12
C57BL/6J m 63.83 48.848   12 14.101 0.7652 16.0, 184.0 0.05
CAST/EiJ f 121.0 0.0   1   0.0 0.0 121.0, 121.0 0.18
CAST/EiJ m 44.0 8.4853   2   6.0 0.1928 38.0, 50.0 -0.54
J:DO f 105.8 133.1   273 8.0565 1.2586 -0.03
J:DO m 111.7 160.6   258 9.9958 1.4373 1.0, 1269.0 1.48
NOD/ShiLtJ f 117.2 150.0   11 45.213 1.2797 7.0, 503.0 0.13
NOD/ShiLtJ m 78.0 81.1   7 30.652 1.0397 3.0, 211.0 0.47
NZO/HlLtJ f 45.7 46.819   10 14.805 1.0245 -0.84
NZO/HlLtJ m 30.222 21.919   9 7.3063 0.7253 10.0, 80.0 -0.94
PWK/PhJ f 126.0 86.25   5 38.571 0.6845 40.0, 243.0 0.24
PWK/PhJ m 105.7 60.2   7 22.755 0.5695 12.0, 182.0 1.3
WSB/EiJ f 58.0 36.77   2   26.0 0.634 32.0, 84.0 -0.67
WSB/EiJ m 25.2 16.392   5 7.3308 0.6505 15.0, 54.0 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 24.3333333333 48.6712472778 119.9165648003 -71.2498981336
A/J m 37.5 59.6098604877 154.5650725302 -79.5650725302
C57BL/6J f 265.0 44.024799627 351.458285916 178.541714084
C57BL/6J m 63.8333333333 42.1505365765 146.6108399595 -18.9441732928
J:DO f 105.7619047619 8.8371536706 123.1167857655 88.4070237583
J:DO m 111.7054263566 9.0904185021 129.5576825533 93.8531701599
NOD/ShiLtJ f 117.1818181818 44.024799627 203.6401040979 30.7235322658
NOD/ShiLtJ m 78.0 55.1880069842 186.3811971298 -30.3811971298
NZO/HlLtJ f 45.7 46.1735993878 136.3782152664 -44.9782152664
NZO/HlLtJ m 30.2222222222 48.6712472778 125.8054536892 -65.3610092447
PWK/PhJ f 126.0 65.2993304777 254.2383618415 -2.2383618415
PWK/PhJ m 105.7142857143 55.1880069842 214.095482844 -2.6669114155
WSB/EiJ f 58.0 103.2473069969 260.762653414 -144.762653414
WSB/EiJ m 25.2 65.2993304777 153.4383618415 -103.0383618415


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 30.9166666667 38.4779994898 106.4818460553 -44.648512722
C57BL/6J both 164.4166666667 30.4747875952 224.2647050781 104.5686282552
J:DO both 108.7336655592 6.3389863847 121.1825103446 96.2848207739
NOD/ShiLtJ both 97.5909090909 35.2983678698 166.9117556935 28.2700624883
NZO/HlLtJ both 37.9611111111 33.5443422651 103.8373072322 -27.91508501
PWK/PhJ both 115.8571428571 42.748446392 199.8088571623 31.905428552
WSB/EiJ both 41.6 61.0819305584 161.556003463 -78.356003463




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA