Project measure / variable:   CSNA03   extinction_active_do_s1

ID, description, units MPD:110271   extinction_active_do_s1   extinction, active lever presses (intravenous self administration), DO   [n]  session 1  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means110.4   n 94.07   n
Median of the strain means114.5   n 92.15   n
SD of the strain means± 48.033 ± 42.559
Coefficient of variation (CV)0.4349 0.4524
Min–max range of strain means55.44   –   198.2   n 35.4   –   149.9   n
Mean sample size per strain40.5   mice 38.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4410.5166 4410.5166 0.2702 0.6034
strain 6 194974.9953 32495.8326 1.9906 0.065
sex:strain 6 53481.1503 8913.525 0.546 0.7732
Residuals 614 10023135.7885 16324.3254


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 55.44 34.431   9 11.477 0.621 7.0, 99.0 -1.15
A/J m 67.86 44.592   7 16.854 0.6572 20.0, 155.0 -0.62
C57BL/6J f 198.2 114.6   12 33.082 0.578 8.0, 476.0 1.83
C57BL/6J m 105.3 58.97   12 17.022 0.5598 18.0, 208.0 0.26
CAST/EiJ f 108.0 0.0   1   0.0 0.0 108.0, 108.0 -0.05
CAST/EiJ m 79.0 9.8995   2   7.0 0.1253 72.0, 86.0 -0.35
J:DO f 121.0 135.7   274 8.1993 1.1213 0.22
J:DO m 119.4 127.3   259 7.9098 1.0661 0.6
NOD/ShiLtJ f 126.3 205.2   10 64.9 1.625 9.0, 700.0 0.33
NOD/ShiLtJ m 144.8 162.4   6 66.3 1.1213 4.0, 459.0 1.19
NZO/HlLtJ f 72.6 56.85   10 17.977 0.783 4.0, 170.0 -0.79
NZO/HlLtJ m 50.89 33.714   9 11.238 0.6625 16.0, 118.0 -1.01
PWK/PhJ f 142.5 81.12   6 33.117 0.5693 52.0, 237.0 0.67
PWK/PhJ m 149.9 63.68   7 24.068 0.4249 70.0, 229.0 1.31
WSB/EiJ f 59.5 17.678   2   12.5 0.2971 47.0, 72.0 -1.06
WSB/EiJ m 35.4 26.754   5 11.965 0.7558 8.0, 78.0 -1.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 55.4444444444 42.5888944684 139.0820109672 -28.1931220784
A/J m 67.8571428571 48.2912671614 162.6932291208 -26.9789434065
C57BL/6J f 198.25 36.8830645287 270.6822573194 125.8177426805
C57BL/6J m 105.3333333333 36.8830645287 177.7655906528 32.9010760139
J:DO f 121.0437956204 7.7186676237 136.2019861511 105.8856050898
J:DO m 119.3976833977 7.939035417 134.9886399394 103.8067268559
NOD/ShiLtJ f 126.3 40.4033728646 205.6455624498 46.9544375502
NOD/ShiLtJ m 144.8333333333 52.1605300784 247.2680139878 42.3986526789
NZO/HlLtJ f 72.6 40.4033728646 151.9455624498 -6.7455624498
NZO/HlLtJ m 50.8888888889 42.5888944684 134.5264554117 -32.7486776339
PWK/PhJ f 142.5 52.1605300784 244.9346806545 40.0653193455
PWK/PhJ m 149.8571428571 48.2912671614 244.6932291208 55.0210565935
WSB/EiJ f 59.5 90.3446882455 236.9220713506 -117.9220713506
WSB/EiJ m 35.4 57.1389978708 147.6115705306 -76.8115705306


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 61.6507936508 32.1941781076 124.8748511599 -1.5732638583
C57BL/6J both 151.7916666667 26.0802650392 203.0090069939 100.5743263394
J:DO both 120.2207395091 5.5363822402 131.0932813698 109.3481976484
NOD/ShiLtJ both 135.5666666667 32.9892158019 200.3520471187 70.7812862146
NZO/HlLtJ both 61.7444444444 29.3523698825 119.3876591673 4.1012297216
PWK/PhJ both 146.1785714286 35.5414102918 215.9760410435 76.3811018136
WSB/EiJ both 47.45 53.448638364 152.4143129393 -57.5143129393




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA