Project measure / variable:   CSNA03   infusions_do_1p0_2nd

ID, description, units MPD:110270   infusions_do_1p0_2nd   dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, DO   [n]  1.0 (2nd) mg/kg  
cocaine study
Data set, strains CSNA03   DO population w/par   6 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains2 strains
Mean of the strain means31.505   n 28.101   n
Median of the strain means27.266   n 28.101   n
SD of the strain means± 18.729 ± 6.8603
Coefficient of variation (CV)0.5945 0.2441
Min–max range of strain means11.0   –   62.5   n 23.25   –   32.952   n
Mean sample size per strain49.5   mice 133.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.3915 2.3915 0.0053 0.9422
strain 1 0.0162 0.0162 0.0 0.9952
sex:strain 1 368.6565 368.6565 0.8116 0.368
Residuals 553 251185.1555 454.2227


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 21.85 7.566   2   5.35 0.3463 16.5, 27.2 -0.52
C57BL/6J f 42.25 2.4749   2   1.75 0.0586 40.5, 44.0 0.57
C57BL/6J m 23.25 0.35355   2   0.25 0.0152 23.0, 23.5 -0.71
J:DO f 32.682 18.361   289 1.0801 0.5618 0.06
J:DO m 32.952 24.205   264 1.4897 0.7346 0.71
NOD/ShiLtJ f 11.0 0.0   1   0.0 0.0 11.0, 11.0 -1.09
PWK/PhJ f 62.5 0.0   1   0.0 0.0 62.5, 62.5 1.65
WSB/EiJ f 18.75 7.4246   2   5.25 0.396 13.5, 24.0 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C57BL/6J f 42.25 15.0702140715 71.8518646664 12.6481353336
C57BL/6J m 23.25 15.0702140715 52.8518646664 -6.3518646664
J:DO f 32.6820069204 1.2536765369 35.1445574194 30.2194564214
J:DO m 32.9518939394 1.3116937702 35.5284055459 30.3753823329


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
C57BL/6J both 32.75 10.6562505639 53.6816792414 11.8183207586
J:DO both 32.8169504299 0.9072272877 34.5989834696 31.0349173902




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA