Project measure / variable:   CSNA03   reinstatement_inf_in_s2

ID, description, units MPD:110221   reinstatement_inf_in_s2   reinstatement, number of infusions (intravenous self administration), founders   [n]  session 2  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, number of infusions (intravenous self administration), founders session 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means54.52   n 42.467   n
Median of the strain means56.0   n 40.5   n
SD of the strain means± 23.059 ± 9.1819
Coefficient of variation (CV)0.4229 0.2162
Min–max range of strain means28.182   –   92.0   n 31.3   –   57.5   n
Mean sample size per strain7.6   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 876.6474 876.6474 0.9377 0.3356
strain 5 13933.7039 2786.7408 2.9808 0.0157
sex:strain 5 5918.9608 1183.7922 1.2662 0.2858
Residuals 87 81335.1323 934.8866


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 40.0 39.598   9 13.199 0.9899 1.0, 106.0 -0.63
A/J m 46.714 43.809   7 16.558 0.9378 0.46
C57BL/6J f 74.0 37.092   12 10.708 0.5012 14.0, 132.0 0.84
C57BL/6J m 40.385 29.89   13 8.29 0.7401 5.0, 121.0 -0.23
CAST/EiJ f 92.0 0.0   1   0.0 0.0 92.0, 92.0 1.63
CAST/EiJ m 40.5 40.305   2   28.5 0.9952 12.0, 69.0 -0.21
NOD/ShiLtJ f 28.182 32.034   11 9.6586 1.1367 2.0, 104.0 -1.14
NOD/ShiLtJ m 32.667 16.621   6 6.7856 0.5088 10.0, 53.0 -1.07
NZO/HlLtJ f 32.6 25.295   10 7.9989 0.7759 -0.95
NZO/HlLtJ m 31.3 15.945   10 5.0422 0.5094 6.0, 62.0 -1.22
PWK/PhJ f 58.86 25.635   7 9.689 0.4355 34.0, 88.0 0.19
PWK/PhJ m 57.5 20.695   6 8.4489 0.3599 23.0, 85.0 1.64
WSB/EiJ f 56.0 42.438   3 24.502 0.7578 7.0, 81.0 0.06
WSB/EiJ m 48.2 22.61   5 10.111 0.4691 14.0, 70.0 0.62


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 40.0 10.1919716692 60.2576472955 19.7423527045
A/J m 46.7142857143 11.5566096026 69.6842986676 23.744272761
C57BL/6J f 74.0 8.8265063802 91.5436371788 56.4563628212
C57BL/6J m 40.3846153846 8.4802330273 57.2399967794 23.5292339898
NOD/ShiLtJ f 28.1818181818 9.2189852457 46.5055496039 9.8580867597
NOD/ShiLtJ m 32.6666666667 12.4825650312 57.4771162982 7.8562170351
NZO/HlLtJ f 32.6 9.6689532968 51.818091647 13.381908353
NZO/HlLtJ m 31.3 9.6689532968 50.518091647 12.081908353
PWK/PhJ f 58.8571428571 11.5566096026 81.8271558105 35.8871299038
PWK/PhJ m 57.5 12.4825650312 82.3104496316 32.6895503684
WSB/EiJ f 56.0 17.6530127604 91.0872743576 20.9127256425
WSB/EiJ m 48.2 13.6739648863 75.3784858501 21.0215141499


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 43.3571428571 7.7044064018 58.670484826 28.0438008883
C57BL/6J both 57.1923076923 6.1200810263 69.3566314243 45.0279839603
NOD/ShiLtJ both 30.4242424242 7.7589322513 45.8459604231 15.0025244253
NZO/HlLtJ both 31.95 6.8369824431 45.5392429251 18.3607570749
PWK/PhJ both 58.1785714286 8.5054343697 75.0840432202 41.2730996369
WSB/EiJ both 52.1 11.1647455774 74.2911407714 29.9088592286




  GWAS USING LINEAR MIXED MODELS