Project measure / variable:   CSNA03   reinstatement_active_in_s1

ID, description, units MPD:110216   reinstatement_active_in_s1   reinstatement, active lever presses (intravenous self administration), founders   [n]  session 1  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, active lever presses (intravenous self administration), founders session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means115.2   n 63.63   n
Median of the strain means103.4   n 62.0   n
SD of the strain means± 61.58 ± 16.301
Coefficient of variation (CV)0.5343 0.2562
Min–max range of strain means48.2   –   202.0   n 40.857   –   93.83   n
Mean sample size per strain7.6   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 48914.0444 48914.0444 7.0097 0.0096
strain 5 93385.841 18677.1682 2.6766 0.0268
sex:strain 5 71075.6331 14215.1266 2.0371 0.0812
Residuals 87 607091.2088 6978.0599


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 54.89 44.577   9 14.859 0.8121 -0.98
A/J m 40.857 44.33   7 16.755 1.085 -1.4
C57BL/6J f 195.8 175.2   12 50.57 0.8945 9.0, 643.0 1.31
C57BL/6J m 61.0 44.972   13 12.473 0.7372 3.0, 169.0 -0.16
CAST/EiJ f 202.0 0.0   1   0.0 0.0 202.0, 202.0 1.41
CAST/EiJ m 65.5 53.03   2   37.5 0.8097 28.0, 103.0 0.11
NOD/ShiLtJ f 106.7 105.7   11 31.883 0.9908 4.0, 351.0 -0.14
NOD/ShiLtJ m 62.0 44.371   6 18.114 0.7157 10.0, 114.0 -0.1
NZO/HlLtJ f 48.2 37.273   10 11.787 0.7733 7.0, 103.0 -1.09
NZO/HlLtJ m 52.8 34.628   10 10.95 0.6558 11.0, 127.0 -0.66
PWK/PhJ f 103.4 75.63   7 28.585 0.7312 29.0, 253.0 -0.19
PWK/PhJ m 93.83 52.5   6 21.433 0.5595 15.0, 144.0 1.85
WSB/EiJ f 95.67 82.95   3 47.893 0.8671 3.0, 163.0 -0.32
WSB/EiJ m 69.4 51.83   5 23.181 0.7469 18.0, 129.0 0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 54.8888888889 27.844927468 110.2336973246 -0.4559195468
A/J m 40.8571428571 31.5731800093 103.6122569197 -21.8979712054
C57BL/6J f 195.8333333333 24.1144145538 243.7633434062 147.9033232605
C57BL/6J m 61.0 23.1683800956 107.049664149 14.950335851
NOD/ShiLtJ f 106.7272727273 25.1866845617 156.7885355478 56.6660099068
NOD/ShiLtJ m 62.0 34.1029321107 129.7832702897 -5.7832702897
NZO/HlLtJ f 48.2 26.4160176243 100.7046953967 -4.3046953967
NZO/HlLtJ m 52.8 26.4160176243 105.3046953967 0.2953046033
PWK/PhJ f 103.4285714286 31.5731800093 166.1836854911 40.673457366
PWK/PhJ m 93.8333333333 34.1029321107 161.6166036231 26.0500630436
WSB/EiJ f 95.6666666667 48.2288291077 191.5266868124 -0.1933534791
WSB/EiJ m 69.4 37.3578903882 143.6528523183 -4.8528523183


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 47.873015873 21.0487866729 89.7097585814 6.0362731646
C57BL/6J both 128.4166666667 16.7203381061 161.6501491573 95.183184176
NOD/ShiLtJ both 84.3636363636 21.1977537593 126.4964672867 42.2308054406
NZO/HlLtJ both 50.5 18.6789451941 87.6264261592 13.3735738408
PWK/PhJ both 98.630952381 23.2372313026 144.8174657593 52.4444390026
WSB/EiJ both 82.5333333333 30.5025897727 143.1605333754 21.9061332913




  GWAS USING LINEAR MIXED MODELS