Project measure / variable:   CSNA03   extinction_inactive_in_s2

ID, description, units MPD:110208   extinction_inactive_in_s2   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 2  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means31.743   n 21.694   n
Median of the strain means31.0   n 18.143   n
SD of the strain means± 16.503 ± 16.202
Coefficient of variation (CV)0.5199 0.7469
Min–max range of strain means7.1111   –   52.18   n 7.4   –   55.83   n
Mean sample size per strain7.0   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4371.6027 4371.6027 2.2936 0.1338
strain 5 5361.402 1072.2804 0.5626 0.7284
sex:strain 5 20989.568 4197.9136 2.2024 0.0618
Residuals 82 156294.6613 1906.0325


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 7.1111 8.8097   9 2.9366 1.2389 -1.49
A/J m 55.83 78.2   6 31.926 1.4007 2.11
C57BL/6J f 52.18 61.7   11 18.604 1.1824 2.0, 206.0 1.24
C57BL/6J m 10.333 12.766   12 3.6852 1.2354 -0.7
CAST/EiJ f 33.0 0.0   1   0.0 0.0 33.0, 33.0 0.08
CAST/EiJ m 24.5 24.749   2   17.5 1.0102 7.0, 42.0 0.17
NOD/ShiLtJ f 51.91 84.26   11 25.405 1.6232 1.22
NOD/ShiLtJ m 18.143 26.429   7 9.9891 1.4567 -0.22
NZO/HlLtJ f 17.8 24.625   10 7.7872 1.3834 -0.84
NZO/HlLtJ m 14.222 13.236   9 4.412 0.9307 3.0, 41.0 -0.46
PWK/PhJ f 29.2 17.612   5 7.8765 0.6032 7.0, 55.0 -0.15
PWK/PhJ m 21.429 8.3038   7 3.1385 0.3875 11.0, 32.0 -0.02
WSB/EiJ f 31.0 36.77   2   26.0 1.1861 5.0, 57.0 -0.05
WSB/EiJ m 7.4 6.6558   5 2.9766 0.8994 1.0, 15.0 -0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 7.1111111111 14.5527105349 36.0610882348 -21.8388660126
A/J m 55.8333333333 17.8233575925 91.2896693425 20.3769973242
C57BL/6J f 52.1818181818 13.1634219619 78.368057766 25.9955785976
C57BL/6J m 10.3333333333 12.6030170171 35.4047489615 -14.7380822948
NOD/ShiLtJ f 51.9090909091 13.1634219619 78.0953304933 25.7228513249
NOD/ShiLtJ m 18.1428571429 16.5012227045 50.9690456844 -14.6833313987
NZO/HlLtJ f 17.8 13.8059134258 45.2643597762 -9.6643597762
NZO/HlLtJ m 14.2222222222 14.5527105349 43.1721993459 -14.7277549015
PWK/PhJ f 29.2 19.5245100078 68.0404700774 -9.6404700774
PWK/PhJ m 21.4285714286 16.5012227045 54.2547599702 -11.397617113
WSB/EiJ f 31.0 30.8709609116 92.4121754181 -30.4121754181
WSB/EiJ m 7.4 19.5245100078 46.2404700774 -31.4404700774


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 31.4722222222 11.5049278549 54.3591887024 8.585255742
C57BL/6J both 31.2575757576 9.1119662489 49.3841793084 13.1309722067
NOD/ShiLtJ both 35.025974026 10.5542175041 56.0216747628 14.0302732891
NZO/HlLtJ both 16.0111111111 10.0297635744 35.9635059134 -3.9412836912
PWK/PhJ both 25.3142857143 12.7817921453 50.7413420225 -0.1127705939
WSB/EiJ both 19.2 18.2635067734 55.5319329427 -17.1319329427




  GWAS USING LINEAR MIXED MODELS