MPD: Project measures / variables set: Wiltshire2 OFT

Project measures / variables set: Wiltshire2 OFT_thig

ID, description, units	MPD:38003 OFT_thig OFT center avoidance, thigmotaxis, 10 min test [%] fluoxetine study
Measures	• control • fluoxetine
Data set, strains	Wiltshire2 inbred 30 strains sex: m age: 10-11wks
Procedure	open field test
Comparison	control group vs. treated group
Ontology mappings	VT:0010471 exploratory behavior trait VT:0010487 response to xenobiotic stimulus trait VT:0010716 anxiety-related behavior trait MP:0001362 abnormal anxiety-related response MP:0013189 abnormal exploration in a new environment MP:0009745 abnormal behavioral response to xenobiotic

Values Means Δ Means Z-scores

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Wiltshire2 - OFT center avoidance, thigmotaxis, 10 min test

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	1034.9022	1034.9022	23.1831	< 0.0001
strain	29	34694.6797	1196.3683	26.8001	< 0.0001
group:strain	29	1842.5399	63.5359	1.4233	0.0715
Residuals	605	27007.4609	44.6404

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Wiltshire2	38003	open field test	fluoxetine	OFT center avoidance, thigmotaxis, 10 min test [%] control OFT_thig_cont	inbred	30	m	10-11wks
Wiltshire2	38004	open field test	fluoxetine	OFT center avoidance, thigmotaxis, 10 min test [%] fluoxetine OFT_thig_fluox	inbred	30	m	10-11wks