Schughart2: Susceptibility to influenza A (H1N1) viral infection in females of 53 BXD recombinant inbred strains of mice (2012)

Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R, Williams RW, Schughart K. Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner. BMC Genomics. 2012 Aug 20;13:41doi: 10.1186/1471-2164-13-411.   PubMed 22905720     FullText

Schughart2 downloads
• Download Schughart2 project data set     animal data, as uploaded
• Download Schughart2 animal data matrix     with factor-related expansion applied as necessary
• Download Schughart2 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Klaus Schughart       Helmholtz Center for Infection Research,  Braunschweig GERMANY
Robert W Williams       University of Tennessee,  Memphis, TN
Participants Nedelko T, Kollmus H, Klawonn F, Spijker S, Lu L, Heßman M, Alberts R
ContactKlaus Schughart     Lab web site
Part of a series: • 9 inbred strains   see Schughart1
• 53 BXD strains   (this project) Schughart2
AcknowledgementsFunding provided by German Ministry of Education FluResearchNet (01KI07137); Helmholtz-Association (Program Infection and Immunity; virtual institute 'GeNeSys')
Project type Phenotype strain survey data set
MPD identifiersSchughart2     MPD:496
Data changelog No updates/corrections.       Initial release date: 04/2014.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Mice infected with influenza A H1N1 (PR8) virus were analyzed for subsequent daily weight loss and survival over a period of 13 d.

Procedures conducted:
• body weight  Influenza A (H1N1) virus vs. baseline. Several timepoints..
• health assessment  Survival rate, susceptibility, influenza A (H1N1) virus.

Mice: BXD w/par   56 strains   ♀   age 9-18wks   1 experimental group