Schughart1: Susceptibility to influenza A (H1N1) viral infection in females of 9 strains of mice (2009)

Srivastava B, Błazejewska P, Hessmann M, Bruder D, Geffers R, Mauel S, Gruber AD, Schughart K. Host genetic background strongly influences the response to influenza a virus infections. PLoS One. 2009;4(3):e4857. Epub 2009 Mar 18.   PubMed 19293935     FullText


         
Schughart1 downloads
• Download Schughart1 project data set     animal data, as uploaded
• Download Schughart1 animal data matrix     with factor-related expansion applied as necessary
• Download Schughart1 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Klaus Schughart       Helmholtz Center for Infection Research,  Braunschweig GERMANY
Participants Srivastava B, Błazejewska P, Hessmann M, Bruder D, Geffers R, Mauel S, Gruber AD
ContactKlaus Schughart     Klaus.Schughart@helmholtz-hzi.de     Lab web site
Part of a series: • 9 inbred strains   (this project) Schughart1
• 53 BXD strains   see Schughart2
AcknowledgementsFunding provided by Helmholtz-Association (Program Infection and Immunity); German Ministry of Education and Research (FluResearchNet 01KI07137); Georg-Christoph-Lichtenberg Foundation
Project type Phenotype strain survey data set
MPD identifiersSchughart1     MPD:393
Data changelog No updates/corrections.       Initial release date: 03/2012.
Formatted citation
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Mice infected with influenza A H1N1 (PR8) virus were analyzed for subsequent daily weight and survival over a period of 2 wks.

Procedures conducted:
• body weight  Influenza A (H1N1) virus vs. baseline. Several timepoints.
• health assessment  Strain susceptibility score, influenza A (H1N1) virus.

Mice: inbred   9 strains   ♀♂   age 10-12wks   1 experimental group