Schughart1: Susceptibility to influenza A (H1N1) viral infection in females of 9 strains of mice (2009)

Srivastava B, Błazejewska P, Hessmann M, Bruder D, Geffers R, Mauel S, Gruber AD, Schughart K. Host genetic background strongly influences the response to influenza a virus infections. PLoS One. 2009;4(3):e4857. Epub 2009 Mar 18.   PubMed 19293935     FullText

Schughart1 downloads
• Download Schughart1 project data set     animal data, as uploaded
• Download Schughart1 animal data matrix     with factor-related expansion applied as necessary
• Download Schughart1 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Klaus Schughart       Helmholtz Center for Infection Research,  Braunschweig GERMANY
Participants Srivastava B, Błazejewska P, Hessmann M, Bruder D, Geffers R, Mauel S, Gruber AD
ContactKlaus Schughart     Lab web site
Part of a series: • 9 inbred strains   (this project) Schughart1
• 53 BXD strains   see Schughart2
AcknowledgementsFunding provided by Helmholtz-Association (Program Infection and Immunity); German Ministry of Education and Research (FluResearchNet 01KI07137); Georg-Christoph-Lichtenberg Foundation
Project type Phenotype strain survey data set
MPD identifiersSchughart1     MPD:393
Data changelog No updates/corrections.       Initial release date: 03/2012.
Formatted citation
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Mice infected with influenza A H1N1 (PR8) virus were analyzed for subsequent daily weight and survival over a period of 2 wks.

Procedures conducted:
• body weight  Influenza A (H1N1) virus vs. baseline. Several timepoints.
• health assessment  Strain susceptibility score, influenza A (H1N1) virus.

Mice: inbred   9 strains   ♀♂   age 10-12wks   1 experimental group