Bilateral ear punctures were made in 6-wk old mice and healing outcomes were measured after 30 d. At 8 wks of age, acute full-thickness articular cartilage injuries were introduced in the trochlear groove. Mouse knee joints were sectioned at indicated times post-injury and stained to evaluate regeneration. Time course analysis showed no significant regeneration until 16 wks post-wounding.
|• health assessment||
||Post-injury wound healing. Ear cartilage and articular cartilage.|
||Post-injury wound healing. Articular cartilage at 12wks and 16wks post-injury.|