Phenotype measure:   Sandell1   articular_16

ID, description, units MPD:49803   articular_16   articular cartilage wound healing at 16 wks post-injury   [score]
Data set, strains Sandell1   LGXSM w/par   10 strains     sex: both     age: 24wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Sandell1 - articular cartilage wound healing at 16 wks post-injury



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains10 strains
Mean of the strain means4.63   score 3.89   score
Median of the strain means4.71   score 2.83   score
SD of the strain means± 2.17 ± 2.51
Coefficient of variation (CV)0.470 0.646
Min–max range of strain means2.26   –   8.00   score 2.00   –   10.1   score
Mean sample size per strain3.7   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18.656 18.656 2.3306 0.1333
strain 7 217.2683 31.0383 3.8775 0.002
sex:strain 7 31.475 4.4964 0.5617 0.7831
Residuals 49 392.2303 8.0047


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C57BL/6J f 2.33 0.335   3 0.193 0.144 2.0, 2.67 -1.06
C57BL/6J m 2.76 0.991   6 0.405 0.359 2.06, 4.66 -0.45
DBA/1J m 2.69 0.5   4 0.25 0.186 2.0, 3.11 -0.48
DBA/2J f 2.26 0.277   3 0.16 0.123 2.0, 2.55 -1.09
DBA/2J m 2.28 0.555   4 0.278 0.244 2.0, 3.11 -0.64
LG/J f 8.0 6.0   3 3.46 0.75 2.0, 14.0 1.55
LG/J m 10.1 1.73   2   1.22 0.172 8.83, 11.3 2.48
LGXSM33 f 3.32 1.91   6 0.782 0.576 2.11, 7.05 -0.6
LGXSM33 m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.75
LGXSM35 f 5.54 3.16   3 1.82 0.57 2.0, 8.06 0.42
LGXSM35 m 5.37 2.35   3 1.36 0.437 2.67, 6.89 0.59
LGXSM5 f 4.71 3.44   4 1.72 0.73 2.0, 9.17 0.04
LGXSM5 m 3.33 1.33   4 0.664 0.399 2.0, 4.61 -0.22
LGXSM6 f 5.82 2.95   11 0.891 0.507 2.67, 11.8 0.55
LGXSM6 m 5.4 3.99   7 1.51 0.738 2.33, 12.9 0.6
MRL/MpJ f 7.23 4.26   4 2.13 0.588 2.0, 12.3 1.2
MRL/MpJ m 2.89 1.26   2   0.89 0.436 2.0, 3.78 -0.4
SM/J f 2.43 0.598   3 0.345 0.246 2.0, 3.11 -1.01
SM/J m 2.04 0.0635   3 0.0367 0.0312 2.0, 2.11 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C57BL/6J f 2.3333 1.6335 5.6159 0.0
C57BL/6J m 2.7583 1.155 5.0795 0.4372
DBA/2J f 2.2567 1.6335 5.5393 0.0
DBA/2J m 2.2775 1.4146 5.1203 0.0
LG/J f 8.0 1.6335 11.2826 4.7174
LG/J m 10.055 2.0006 14.0753 6.0347
LGXSM35 f 5.54 1.6335 8.8226 2.2574
LGXSM35 m 5.3733 1.6335 8.6559 2.0907
LGXSM5 f 4.71 1.4146 7.5528 1.8672
LGXSM5 m 3.3325 1.4146 6.1753 0.4897
LGXSM6 f 5.8227 0.8531 7.537 4.1085
LGXSM6 m 5.4043 1.0694 7.5532 3.2553
MRL/MpJ f 7.235 1.4146 10.0778 4.3922
MRL/MpJ m 2.89 2.0006 6.9103 0.0
SM/J f 2.4267 1.6335 5.7093 0.0
SM/J m 2.0367 1.6335 5.3193 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
C57BL/6J both 2.5458 1.0003 4.556 0.5357
DBA/2J both 2.2671 1.0804 4.4383 0.0959
LG/J both 9.0275 1.2914 11.6226 6.4324
LGXSM35 both 5.4567 1.155 7.7778 3.1355
LGXSM5 both 4.0212 1.0003 6.0314 2.0111
LGXSM6 both 5.6135 0.684 6.988 4.239
MRL/MpJ both 5.0625 1.2251 7.5244 2.6006
SM/J both 2.2317 1.155 4.5528 0.0




GWAS analysis not available: At least 12 strains are required