McMullan3: Body composition responses following voluntary exercise in aging females of 43 Collaborative Cross strains of mice (2017)

McMullan RC, Pomp D, Pardo-Manuel de Villena F

       
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Participants Rachel C McMullan       University of North Carolina Chapel Hill, NC
Daniel Pomp       University of North Carolina Chapel Hill, NC
Fernando Pardo-Manuel de Villena       University of North Carolina Chapel Hill, NC
ContactFernando Pardo-Manuel de Villena     fernando@med.unc.edu     Lab web site
Part of a series: • amount of voluntary exercise   see McMullan2
• body composition after exercise   (this project) McMullan3
AcknowledgementsFunding provided by NIH MH100241. Acknowledgements: Kunjie Hua and the Animal Metabolism & Phenotyping Core in NORC (Nutrition Obesity Research Center) University of North Carolina – Chapel Hill (DK05350). System Genetics Core and UNC U19 Project (NIH 1U19Al100625-01) for providing retired breeders.
Project type Phenotype strain survey data set
MPD identifiersMcMullan3     MPD:606
Data changelog No updates/corrections.       Initial release date: 02/2018.
Formatted citation
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Female mice (n =186) from 43 CC strains were obtained from other experiments or from the System Genetics Core at UNC-Chapel Hill. The female mice in the experiment were all retired breeders and varied in life history and age. Mice had voluntary access to running wheels for 4 weeks. Body composition measures were taken before access to running wheels, after 2 weeks of exercise, and after 4 weeks of exercise.

Summary of procedures that were conducted
• body weight Body weight before, during, and after several weeks of exercise.
• MRI Body composition (fat and lean mass) before, during, and after several weeks of exercise.
• intake monitoring Food intake, before, during, and after several weeks of exercise.
Mice: CC   43 strains   ♀   age 20-88wks   1 cohort