Maurer1 animal documentation

Drug study: Cardiovascular response to beta-adrenergic blockade or activation in males of 23 inbred strains of mice   (2009)

Maurer F, Beckmann J, Abriel H, Pedrazzini T
With: Berthonneche C, Peter B, Schüpfer F, Hayoz P, Kutalik Z, Bergmann S,




Maurer1 Animal Documentation

Acclimation & testing periods

Vendor
Mice were purchased in two to six lots per strain, either from Charles River, France (strains Balb/cByJ, C3H/HeOuJ, CBA/J, and DBA/2J) or from The Jackson Laboratory JAX® (Bar Harbor, ME).
Ages
Males 7-13 wks of age on the day of sacrifice
Feed
Commercial chow diet, ad libitum (Provimi Kliba AG, Switzerland)
Water
Tap water, ad libitum
Housing
4-5 mice/cage
Relative humidity
30-60%
Room temperature
25°C
Bedding
Wood chips, saw dust
Photoperiod
12h/12h light/dark cycle (6:00 A.M. to 6:00 P.M.)
Health status
All animal procedures have been approved by the "Service vétérinaire cantonal vaudois" (authorization nu 1649) and were performed in accordance with the National Institutes of Health (NIH) guidelines for the care and use of laboratory animals. Sentinel mice were periodically examined throughout the study and were free of microbiological infections.