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      • abnormal chromosome stability

    • chromosomal instability   MP:0008866   (3)
    Definition: abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity [MGI:llw2, PMID:12446840];   [MGI annotations / genotypes]
      (No descendants that are mapped to MPD data)





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