MPD: Phenotype measures mapped to VT:0002121, metabolism trait

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Xenakis1:9	Xenakis1	body weight	haloperidol	body weight, treatment group [g] bw_Rx 111152 pre-treatment post-treatment	CC RIX	73	both	7-13wks	N=3	2020

Xenakis1:13	Xenakis1	inclined screen test	haloperidol	latency to move all four paws (extrapyramidal symptoms), treatment group [s] latency_Rx 111156 pre-treatment post-treatment	CC RIX	73	both	7-9wks	N=3	2020

Xenakis1:17	Xenakis1	open field test	haloperidol	distance traveled, 30 min test, treatment group [cm] distance_Rx 111160 pre-treatment post-treatment	CC RIX	73	both	7-13wks	N=3	2020

Xenakis1:21	Xenakis1	open field test	haloperidol	vertical activity (beam breaks), 30 min test, treatment group [n] vertical_Rx 111164 pre-treatment post-treatment	CC RIX	73	both	7-13wks	N=3	2020

Xenakis1:25	Xenakis1	open field test	haloperidol	time spent in center of arena, 30 min test, treatment group [s] center_Rx 111168 pre-treatment post-treatment	CC RIX	73	both	7-13wks	N=3	2020

Xenakis1:29	Xenakis1	open field test	haloperidol	stereotypy activity (beam breaks), 30 min test, treatment group [n] stereotypy_Rx 111172 pre-treatment post-treatment	CC RIX	73	both	7-13wks	N=3	2020

Xenakis1:31	Xenakis1	behavior observation	haloperidol	subtle vacuous chewing movements, 15 min test, treatment group, post-treatment [n] subtle_vcm_Rx_post 111174	CC RIX	73	both	11-13wks	N=5	2020

Xenakis1:32	Xenakis1	behavior observation	haloperidol	overt vacuous chewing movements, 15 min test, treatment group, post-treatment [n] overt_vcm_Rx_post 111175	CC RIX	73	both	11-13wks	N=5	2020

Xenakis1:33	Xenakis1	behavior observation	haloperidol	tongue protrusions, 15 min test, treatment group, post-treatment [n] tongue_Rx_post 111176	CC RIX	73	both	11-13wks	N=5	2020

Xenakis1:34	Xenakis1	behavior observation	haloperidol	jaw tremors, 15 min test, treatment group, post-treatment [n] jawtremor_Rx_post 111177	CC RIX	73	both	11-13wks	N=5	2020

Xenakis1:36	Xenakis1	drug and metabolite quantification	haloperidol	plasma haloperidol concentration, treatment group, post-treatment [ng/dL] haloperidol_conc_post 111179	CC RIX	53	both	11-13wks	N=2	2020

Xenakis1

body weight

haloperidol

body weight, treatment group [g] bw_Rx 111152 pre-treatment post-treatment

CC RIX

73

both

7-13wks

N=3

2020

Xenakis1

inclined screen test

haloperidol

latency to move all four paws (extrapyramidal symptoms), treatment group [s] latency_Rx 111156 pre-treatment post-treatment

CC RIX

73

both

7-9wks

N=3

2020

Xenakis1

open field test

haloperidol

distance traveled, 30 min test, treatment group [cm] distance_Rx 111160 pre-treatment post-treatment

CC RIX

73

both

7-13wks

N=3

2020

Xenakis1

open field test

haloperidol

vertical activity (beam breaks), 30 min test, treatment group [n] vertical_Rx 111164 pre-treatment post-treatment

CC RIX

73

both

7-13wks

N=3

2020

Xenakis1

open field test

haloperidol

time spent in center of arena, 30 min test, treatment group [s] center_Rx 111168 pre-treatment post-treatment

CC RIX

73

both

7-13wks

N=3

2020

Xenakis1

open field test

haloperidol

stereotypy activity (beam breaks), 30 min test, treatment group [n] stereotypy_Rx 111172 pre-treatment post-treatment

CC RIX

73

both

7-13wks

N=3

2020

Xenakis1

behavior observation

haloperidol

subtle vacuous chewing movements, 15 min test, treatment group, post-treatment [n] subtle_vcm_Rx_post 111174

CC RIX

73

both

11-13wks

N=5

2020

Xenakis1

behavior observation

haloperidol

overt vacuous chewing movements, 15 min test, treatment group, post-treatment [n] overt_vcm_Rx_post 111175

CC RIX

73

both

11-13wks

N=5

2020

Xenakis1

behavior observation

haloperidol

tongue protrusions, 15 min test, treatment group, post-treatment [n] tongue_Rx_post 111176

CC RIX

73

both

11-13wks

N=5

2020

Xenakis1

behavior observation

haloperidol

jaw tremors, 15 min test, treatment group, post-treatment [n] jawtremor_Rx_post 111177

CC RIX

73

both

11-13wks

N=5

2020

Xenakis1

drug and metabolite quantification

haloperidol

plasma haloperidol concentration, treatment group, post-treatment [ng/dL] haloperidol_conc_post 111179

CC RIX

53

both

11-13wks

N=2

2020

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