MPD: Phenotype measures mapped to MP:0010147, abnormal endocrine pancreas physiology

Phenotype measures associated with ontology term
MP:0010147 'abnormal endocrine pancreas physiology'

All measures in this list are mapped to the ontology descendants of MP:0010147. None are mapped to MP:0010147 directly.

MP:0003564 abnormal insulin secretion
MP:0003565 abnormal glucagon secretion

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)	Year
Attie2:100	Attie2	hormone quantification	high-fat high-sucrose diet	amount of insulin per islet after diet [ng/mL] INS_per_islet 110717	DO population	both	19-26wks	N=241	2018

Attie2:101	Attie2	hormone quantification	high-fat high-sucrose diet	whole pancreas insulin content after diet (insulin content per islet times number of islets) [ng/mL] INS_per_pancreas 110718	DO population	both	19-26wks	N=241	2018

Attie2:102	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose [ng/mL] INS_GLU 110719 3.3 mM 8.3 mM 16.7 mM	DO population	both	19-26wks	N=242	2018

Attie2:105	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] INS_GLU3p3_KCl 110722	DO population	both	19-26wks	N=240	2018

Attie2:106	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 [ng/mL] INS_GLU8p3_GLP1 110723	DO population	both	19-26wks	N=240	2018

Attie2:107	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) [ng/mL] INS_GLU8p3_AA 110724	DO population	both	19-26wks	N=240	2018

Attie2:108	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid [ng/mL] INS_GLU16p7_PA 110725	DO population	both	19-26wks	N=240	2018

Attie2:109	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_fc_G3p3 110726	DO population	both	19-26wks	N=240	2018

Attie2:110	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose, expressed as fold-change over that observed with 3.3.mM glucose [ratio] INS_GLU16p7_fc_G3p3 110727	DO population	both	19-26wks	N=240	2018

Attie2:111	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU3p3__KCl_fc_G3p3 110728	DO population	both	19-26wks	N=240	2018

Attie2:112	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G3p3 110729	DO population	both	19-26wks	N=240	2018

Attie2:113	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G3p3 110730	DO population	both	19-26wks	N=240	2018

Attie2:114	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus palmitic acid, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU16p7_PA_fc_G3p3 110731	DO population	both	19-26wks	N=240	2018

Attie2:115	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G8p3 110732	DO population	both	19-26wks	N=240	2018

Attie2:116	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as fold-change over that observed with 8.3 mM glucose [ratio] INS_GLU8p3_AA_fc_G8p3 110733	DO population	both	19-26wks	N=240	2018

Attie2:117	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as fold-change over that observed with 16.7 mM glucose [ratio] INS_GLU16p7_PA_fc_G16p7 110734	DO population	both	19-26wks	N=240	2018

Attie2:118	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose, expressed as a percentage of total insulin per mouse [%] INS_pct_GLU 110735 3.3 mM 8.3 mM 16.7 mM	DO population	both	19-26wks	N=241	2018

Attie2:121	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total insulin per mouse [%] INS_GLU3p3_KCl_pct 110738	DO population	both	19-26wks	N=239	2018

Attie2:122	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_GLP1_pct 110739	DO population	both	19-26wks	N=239	2018

Attie2:123	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu), expressed as a percentage of total insulin per mouse [%] INS_GLU8p3_AA_pct 110740	DO population	both	19-26wks	N=239	2018

Attie2:124	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid, expressed as a percentage of total insulin per mouse [%] INS_GLU16p7_PA_pct 110741	DO population	both	19-26wks	N=239	2018

Attie2:125	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose (geometric mean) [ng/mL] INS_gm_GLU 110742 3.3 mM 8.3 mM 16.7 mM	DO population	both	19-26wks	N=242	2018

Attie2:128	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl (geometric mean) [ng/mL] INS_gm_GLU3p3_KCl 110745	DO population	both	19-26wks	N=240	2018

Attie2:129	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 (geometric mean) [ng/mL] INS_gm_GLU8p3_GLP1 110746	DO population	both	19-26wks	N=240	2018

Attie2:130	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) (geometric mean) [ng/mL] INS_gm_GLU8p3_AA 110747	DO population	both	19-26wks	N=240	2018

Attie2:131	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid (geometric mean) [ng/mL] INS_gm_GLU16p7_PA 110748	DO population	both	19-26wks	N=240	2018

Attie2:132	Attie2	hormone quantification	high-fat high-sucrose diet	amount of glucagon per islet after diet [ng/mL] GCG_per_islet 110749	DO population	both	19-26wks	N=241	2018

Attie2:133	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] GCG_GLU3p3_KCl 110750	DO population	both	19-26wks	N=182	2018

Attie2:134	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo glucagon secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as a percentage of total glucagon per mouse [%] GCG_GLU3p3_KCl_pct 110751	DO population	both	19-26wks	N=182	2018

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