MPD: Project measures / variables set: Neuner1 grip

Project measures / variables set: Neuner1 grip_strength

ID, description, units	MPD:65950 grip_strength mean grip strength across 3 trials [g]
Measures	• 6 mo • 14 mo
Data set, strains	Neuner1 F1 AD-BXD 55 strains sex: both age: 23-57wks
Procedure	grip strength
Comparison	timecourse, same cohort
Ontology mappings	VT:0010080 skeletal muscle physiology trait VT:0004262 physical strength trait MA:0000615 forelimb muscle MP:0001515 abnormal grip strength

Values Means Δ Means Z-scores

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Neuner1 - mean grip strength across 3 trials

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
within group	1	123.407	123.407	647.7187	< 0.0001
within group:sex	1	0.0297	0.0297	0.1559	0.6938
within group:strain	17	7.435	0.4374	2.2955	0.0054
within group:sex:strain	17	2.2022	0.1295	0.6799	0.8162
within Residuals	106	20.1957	0.1905
between sex	1	1.9497	1.9497	10.0732	0.002
between strain	17	10.4415	0.6142	3.1734	0.0001
between sex:strain	17	3.3195	0.1953	1.0089	0.4549
between Residuals	106	20.5162	0.1935

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Neuner1	65950	grip strength	(none)	mean grip strength across 3 trials [g] 6 mo grip_strength_6mo	F1 AD-BXD	55	both	23-57wks
Neuner1	65951	grip strength	(none)	mean grip strength across 3 trials [g] 14 mo grip_strength_14mo	F1 AD-BXD	51	both	23-57wks