Phenotype measure:   Neuner1   grip_strength_14mo

ID, description, units MPD:65951   grip_strength_14mo   mean grip strength across 3 trials   [g]  14 mo
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 23-57wks
Procedure grip strength
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - mean grip strength across 3 trials 14 mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested49 strains35 strains
Mean of the strain means-1.6453   g -1.7622   g
Median of the strain means-1.5917   g -1.685   g
SD of the strain means± 0.32283 ± 0.2432
Coefficient of variation (CV)-0.1962 -0.138
Min–max range of strain means-2.44   –   -1.0467   g -2.3911   –   -1.3089   g
Mean sample size per strain4.6   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6616 1.6616 6.3791 0.0122
strain 24 11.3176 0.4716 1.8104 0.0141
sex:strain 24 2.8388 0.1183 0.4541 0.9879
Residuals 228 59.3892 0.2605


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f -1.55 0.0   1   0.0 0.0 -1.55, -1.55 0.3
(B6.5XFAD x B6)F1-ADtg m -1.8201 0.52665   33 0.09168 -0.2893 -3.133333333, -0.936666667 -0.24
(B6.5XFAD x B6)F1-Ntg f -1.6039 0.42049   11 0.12678 -0.2622 -2.65, -1.143333333 0.13
(B6.5XFAD x B6)F1-Ntg m -1.8246 0.47706   13 0.13231 -0.2615 -2.776666667, -1.213333333 -0.26
(B6.5XFAD x BXD100)F1-ADtg f -2.0933 1.3954   2   0.98667 -0.6666 -3.08, -1.106666667 -1.39
(B6.5XFAD x BXD100)F1-ADtg m -2.0657 0.30614   7 0.11571 -0.1482 -2.46, -1.686666667 -1.25
(B6.5XFAD x BXD100)F1-Ntg f -1.5092 0.35389   4 0.17695 -0.2345 -1.88, -1.193333333 0.42
(B6.5XFAD x BXD100)F1-Ntg m -1.6828 0.33852   6 0.1382 -0.2012 -2.146666667, -1.2 0.33
(B6.5XFAD x BXD14)F1-ADtg f -2.065 0.45962   2   0.325 -0.2226 -2.39, -1.74 -1.3
(B6.5XFAD x BXD14)F1-Ntg f -1.3733 0.37241   2   0.26333 -0.2712 -1.636666667, -1.11 0.84
(B6.5XFAD x BXD16)F1-ADtg f -1.59 0.46512   4 0.23256 -0.2925 -2.093333333, -1.103333333 0.17
(B6.5XFAD x BXD22)F1-ADtg f -1.5233 0.74953   2   0.53 -0.492 -2.053333333, -0.993333333 0.38
(B6.5XFAD x BXD22)F1-Ntg f -1.1722 0.28607   3 0.16516 -0.244 -1.363333333, -0.843333333 1.47
(B6.5XFAD x BXD32)F1-ADtg f -1.1267 0.37427   3 0.21608 -0.3322 -1.45, -0.716666667 1.61
(B6.5XFAD x BXD32)F1-ADtg m -1.6778 0.72116   3 0.41636 -0.4298 -2.51, -1.236666667 0.35
(B6.5XFAD x BXD32)F1-Ntg f -1.2489 0.55367   3 0.31966 -0.4433 -1.626666667, -0.613333333 1.23
(B6.5XFAD x BXD32)F1-Ntg m -2.1533 0.0   1   0.0 0.0 -2.153333333, -2.153333333 -1.61
(B6.5XFAD x BXD42)F1-ADtg f -2.44 0.17913   2   0.12667 -0.0734 -2.566666667, -2.313333333 -2.46
(B6.5XFAD x BXD42)F1-Ntg f -1.54 0.0   1   0.0 0.0 -1.54, -1.54 0.33
(B6.5XFAD x BXD44)F1-ADtg f -1.7839 0.24706   12 0.07132 -0.1385 -2.176666667, -1.396666667 -0.43
(B6.5XFAD x BXD44)F1-ADtg m -1.95 0.39208   8 0.13862 -0.2011 -2.556666667, -1.336666667 -0.77
(B6.5XFAD x BXD44)F1-Ntg f -2.1133 0.0   1   0.0 0.0 -2.113333333, -2.113333333 -1.45
(B6.5XFAD x BXD44)F1-Ntg m -1.7589 0.16654   3 0.09615 -0.0947 -1.86, -1.566666667 0.01
(B6.5XFAD x BXD51)F1-ADtg f -1.754 0.43541   5 0.19472 -0.2482 -2.146666667, -1.146666667 -0.34
(B6.5XFAD x BXD51)F1-Ntg f -1.7942 0.36828   4 0.18414 -0.2053 -2.286666667, -1.46 -0.46
(B6.5XFAD x BXD55)F1-ADtg f -1.8867 0.26358   4 0.13179 -0.1397 -2.246666667, -1.676666667 -0.75
(B6.5XFAD x BXD55)F1-Ntg f -1.8617 0.33705   2   0.23833 -0.181 -2.1, -1.623333333 -0.67
(B6.5XFAD x BXD56)F1-ADtg m -1.3089 0.30281   3 0.17483 -0.2313 -1.643333333, -1.053333333 1.86
(B6.5XFAD x BXD56)F1-Ntg f -1.5917 0.13906   2   0.09833 -0.0874 -1.69, -1.493333333 0.17
(B6.5XFAD x BXD56)F1-Ntg m -1.6067 0.0   1   0.0 0.0 -1.606666667, -1.606666667 0.64
(B6.5XFAD x BXD60)F1-ADtg f -1.2458 0.2951   4 0.14755 -0.2369 -1.566666667, -0.88 1.24
(B6.5XFAD x BXD60)F1-ADtg m -1.5927 0.46107   5 0.2062 -0.2895 -2.006666667, -0.953333333 0.7
(B6.5XFAD x BXD60)F1-Ntg f -1.3722 0.06619   3 0.03822 -0.0482 -1.42, -1.296666667 0.85
(B6.5XFAD x BXD61)F1-ADtg f -1.6957 0.48894   7 0.1848 -0.2883 -2.4, -1.05 -0.16
(B6.5XFAD x BXD61)F1-ADtg m -2.0556 0.52765   3 0.30464 -0.2567 -2.54, -1.49333 -1.21
(B6.5XFAD x BXD61)F1-Ntg f -1.72 0.38562   5 0.17246 -0.2242 -2.16, -1.24 -0.23
(B6.5XFAD x BXD61)F1-Ntg m -2.3911 0.76341   6 0.31166 -0.3193 -3.4, -1.57 -2.59
(B6.5XFAD x BXD62)F1-ADtg f -1.1717 0.02593   2   0.01833 -0.0221 -1.19, -1.153333333 1.47
(B6.5XFAD x BXD62)F1-ADtg m -1.655 0.38891   2   0.275 -0.235 -1.93, -1.38 0.44
(B6.5XFAD x BXD62)F1-Ntg f -1.39 0.04714   2   0.03333 -0.0339 -1.423333333, -1.356666667 0.79
(B6.5XFAD x BXD62)F1-Ntg m -1.5144 0.15027   3 0.08676 -0.0992 -1.636666667, -1.346666667 1.02
(B6.5XFAD x BXD65)F1-ADtg f -1.7176 0.78222   7 0.29565 -0.4554 -2.673333333, -0.493333333 -0.22
(B6.5XFAD x BXD65)F1-ADtg m -1.6217 0.0825   2   0.05833 -0.0509 -1.68, -1.563333333 0.58
(B6.5XFAD x BXD65)F1-Ntg f -1.8758 0.79783   8 0.28208 -0.4253 -2.806666667, -0.38 -0.71
(B6.5XFAD x BXD65)F1-Ntg m -1.8517 0.70004   2   0.495 -0.3781 -2.346666667, -1.356666667 -0.37
(B6.5XFAD x BXD66)F1-ADtg f -1.3856 0.13701   3 0.0791 -0.0989 -1.543333333, -1.296666667 0.8
(B6.5XFAD x BXD66)F1-ADtg m -1.9787 0.46418   5 0.20759 -0.2346 -2.78667, -1.666666667 -0.89
(B6.5XFAD x BXD66)F1-Ntg f -1.7233 0.0   1   0.0 0.0 -1.723333333, -1.723333333 -0.24
(B6.5XFAD x BXD66)F1-Ntg m -1.5722 0.24887   3 0.14369 -0.1583 -1.83, -1.333333333 0.78
(B6.5XFAD x BXD68)F1-ADtg f -1.3867 0.26742   3 0.15439 -0.1928 -1.686666667, -1.173333333 0.8
(B6.5XFAD x BXD68)F1-ADtg m -1.6 0.33079   7 0.12503 -0.2067 -2.076666667, -1.13 0.67
(B6.5XFAD x BXD68)F1-Ntg f -2.0467 0.41209   10 0.13031 -0.2013 -2.55, -1.37 -1.24
(B6.5XFAD x BXD68)F1-Ntg m -2.115 1.162   2   0.82167 -0.5494 -2.936666667, -1.293333333 -1.45
(B6.5XFAD x BXD69)F1-ADtg f -1.5256 0.28308   6 0.11557 -0.1856 -1.946666667, -1.096666667 0.37
(B6.5XFAD x BXD69)F1-ADtg m -1.9733 0.21408   5 0.09574 -0.1085 -2.24667, -1.74 -0.87
(B6.5XFAD x BXD69)F1-Ntg f -1.5892 0.39221   4 0.19611 -0.2468 -2.1, -1.206666667 0.17
(B6.5XFAD x BXD69)F1-Ntg m -1.7544 0.63289   6 0.25838 -0.3607 -2.95667, -1.20333 0.03
(B6.5XFAD x BXD70)F1-ADtg f -1.0467 0.0   1   0.0 0.0 -1.046666667, -1.046666667 1.85
(B6.5XFAD x BXD70)F1-ADtg m -1.4678 0.21225   3 0.12254 -0.1446 -1.66, -1.24 1.21
(B6.5XFAD x BXD70)F1-Ntg f -1.7256 0.143   3 0.08256 -0.0829 -1.833333333, -1.563333333 -0.25
(B6.5XFAD x BXD70)F1-Ntg m -1.4 0.06128   2   0.04333 -0.0438 -1.443333333, -1.356666667 1.49
(B6.5XFAD x BXD75)F1-ADtg f -2.125 0.37941   4 0.1897 -0.1785 -2.496666667, -1.75 -1.49
(B6.5XFAD x BXD75)F1-ADtg m -1.9658 0.33723   4 0.16861 -0.1715 -2.363333333, -1.66 -0.84
(B6.5XFAD x BXD75)F1-Ntg f -2.0856 0.20403   6 0.0833 -0.0978 -2.253333333, -1.726666667 -1.36
(B6.5XFAD x BXD75)F1-Ntg m -1.5233 0.0   1   0.0 0.0 -1.523333333, -1.523333333 0.98
(B6.5XFAD x BXD77)F1-ADtg f -1.2507 0.40542   5 0.18131 -0.3242 -1.74333, -0.886666667 1.22
(B6.5XFAD x BXD77)F1-ADtg m -1.6711 0.16372   3 0.09452 -0.098 -1.86, -1.57 0.37
(B6.5XFAD x BXD77)F1-Ntg f -1.5003 0.29632   10 0.09371 -0.1975 -2.03, -1.166666667 0.45
(B6.5XFAD x BXD77)F1-Ntg m -1.6817 0.29639   6 0.121 -0.1762 -2.026666667, -1.273333333 0.33
(B6.5XFAD x BXD81)F1-ADtg f -1.73 0.47909   6 0.19559 -0.2769 -2.273333333, -0.88 -0.26
(B6.5XFAD x BXD81)F1-Ntg f -2.328 0.54893   5 0.24549 -0.2358 -2.953333333, -1.84 -2.11
(B6.5XFAD x BXD87)F1-ADtg f -1.58 0.46052   10 0.14563 -0.2915 -2.38, -1.02 0.2
(B6.5XFAD x BXD87)F1-ADtg m -1.7092 0.53128   4 0.26564 -0.3108 -2.45, -1.186666667 0.22
(B6.5XFAD x BXD87)F1-Ntg f -1.42 0.33045   3 0.19079 -0.2327 -1.76, -1.1 0.7
(B6.5XFAD x BXD87)F1-Ntg m -1.4233 0.0   1   0.0 0.0 -1.423333333, -1.423333333 1.39
(B6.5XFAD x BXD89)F1-ADtg m -1.6233 0.0   1   0.0 0.0 -1.623333333, -1.623333333 0.57
(B6.5XFAD x BXD89)F1-Ntg f -2.0083 0.46905   2   0.33167 -0.2336 -2.34, -1.676666667 -1.12
(B6.5XFAD x BXD89)F1-Ntg m -1.685 0.20035   2   0.14167 -0.1189 -1.826666667, -1.543333333 0.32
(B6.5XFAD x BXD99)F1-ADtg f -1.32 0.0   1   0.0 0.0 -1.32, -1.32 1.01
(B6.5XFAD x BXD99)F1-Ntg f -1.3267 0.0   1   0.0 0.0 -1.326666667, -1.326666667 0.99
(B6.5XFAD x D2)F1-ADtg f -1.897 0.5799   19 0.13304 -0.3057 -3.36, -1.253333333 -0.78
(B6.5XFAD x D2)F1-ADtg m -1.9696 0.83345   8 0.29467 -0.4232 -3.996666667, -1.57 -0.85
(B6.5XFAD x D2)F1-Ntg f -1.8074 0.53395   13 0.14809 -0.2954 -3.1, -1.353333333 -0.5
(B6.5XFAD x D2)F1-Ntg m -2.034 1.1394   5 0.50955 -0.5602 -4.066666667, -1.4 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f -1.6039 0.1539 -1.3007 -1.9072
(B6.5XFAD x B6)F1-Ntg m -1.8246 0.1416 -1.5457 -2.1035
(B6.5XFAD x BXD100)F1-ADtg f -2.0933 0.3609 -1.3822 -2.8044
(B6.5XFAD x BXD100)F1-ADtg m -2.0657 0.1929 -1.6856 -2.4458
(B6.5XFAD x BXD100)F1-Ntg f -1.5092 0.2552 -1.0063 -2.012
(B6.5XFAD x BXD100)F1-Ntg m -1.6828 0.2084 -1.2722 -2.0933
(B6.5XFAD x BXD32)F1-ADtg f -1.1267 0.2947 -0.5461 -1.7073
(B6.5XFAD x BXD32)F1-ADtg m -1.6778 0.2947 -1.0972 -2.2584
(B6.5XFAD x BXD44)F1-ADtg f -1.7839 0.1473 -1.4936 -2.0742
(B6.5XFAD x BXD44)F1-ADtg m -1.95 0.1804 -1.5944 -2.3056
(B6.5XFAD x BXD60)F1-ADtg f -1.2458 0.2552 -0.743 -1.7487
(B6.5XFAD x BXD60)F1-ADtg m -1.5927 0.2282 -1.1429 -2.0424
(B6.5XFAD x BXD61)F1-ADtg f -1.6957 0.1929 -1.3156 -2.0758
(B6.5XFAD x BXD61)F1-ADtg m -2.0556 0.2947 -1.4749 -2.6362
(B6.5XFAD x BXD61)F1-Ntg f -1.72 0.2282 -1.2703 -2.1697
(B6.5XFAD x BXD61)F1-Ntg m -2.3911 0.2084 -1.9806 -2.8017
(B6.5XFAD x BXD62)F1-ADtg f -1.1717 0.3609 -0.4606 -1.8828
(B6.5XFAD x BXD62)F1-ADtg m -1.655 0.3609 -0.9439 -2.3661
(B6.5XFAD x BXD62)F1-Ntg f -1.39 0.3609 -0.6789 -2.1011
(B6.5XFAD x BXD62)F1-Ntg m -1.5144 0.2947 -0.9338 -2.0951
(B6.5XFAD x BXD65)F1-ADtg f -1.7176 0.1929 -1.3375 -2.0977
(B6.5XFAD x BXD65)F1-ADtg m -1.6217 0.3609 -0.9106 -2.3328
(B6.5XFAD x BXD65)F1-Ntg f -1.8758 0.1804 -1.5203 -2.2314
(B6.5XFAD x BXD65)F1-Ntg m -1.8517 0.3609 -1.1406 -2.5628
(B6.5XFAD x BXD66)F1-ADtg f -1.3856 0.2947 -0.8049 -1.9662
(B6.5XFAD x BXD66)F1-ADtg m -1.9787 0.2282 -1.5289 -2.4284
(B6.5XFAD x BXD68)F1-ADtg f -1.3867 0.2947 -0.8061 -1.9673
(B6.5XFAD x BXD68)F1-ADtg m -1.6 0.1929 -1.2199 -1.9801
(B6.5XFAD x BXD68)F1-Ntg f -2.0467 0.1614 -1.7287 -2.3647
(B6.5XFAD x BXD68)F1-Ntg m -2.115 0.3609 -1.4039 -2.8261
(B6.5XFAD x BXD69)F1-ADtg f -1.5256 0.2084 -1.115 -1.9361
(B6.5XFAD x BXD69)F1-ADtg m -1.9733 0.2282 -1.5236 -2.4231
(B6.5XFAD x BXD69)F1-Ntg f -1.5892 0.2552 -1.0863 -2.092
(B6.5XFAD x BXD69)F1-Ntg m -1.7544 0.2084 -1.3439 -2.165
(B6.5XFAD x BXD70)F1-Ntg f -1.7256 0.2947 -1.1449 -2.3062
(B6.5XFAD x BXD70)F1-Ntg m -1.4 0.3609 -0.6889 -2.1111
(B6.5XFAD x BXD75)F1-ADtg f -2.125 0.2552 -1.6222 -2.6278
(B6.5XFAD x BXD75)F1-ADtg m -1.9658 0.2552 -1.463 -2.4687
(B6.5XFAD x BXD77)F1-ADtg f -1.2507 0.2282 -0.8009 -1.7004
(B6.5XFAD x BXD77)F1-ADtg m -1.6711 0.2947 -1.0905 -2.2517
(B6.5XFAD x BXD77)F1-Ntg f -1.5003 0.1614 -1.1823 -1.8183
(B6.5XFAD x BXD77)F1-Ntg m -1.6817 0.2084 -1.2711 -2.0922
(B6.5XFAD x BXD87)F1-ADtg f -1.58 0.1614 -1.262 -1.898
(B6.5XFAD x BXD87)F1-ADtg m -1.7092 0.2552 -1.2063 -2.212
(B6.5XFAD x BXD89)F1-Ntg f -2.0083 0.3609 -1.2972 -2.7194
(B6.5XFAD x BXD89)F1-Ntg m -1.685 0.3609 -0.9739 -2.3961
(B6.5XFAD x D2)F1-ADtg f -1.897 0.1171 -1.6663 -2.1277
(B6.5XFAD x D2)F1-ADtg m -1.9696 0.1804 -1.614 -2.3251
(B6.5XFAD x D2)F1-Ntg f -1.8074 0.1416 -1.5285 -2.0864
(B6.5XFAD x D2)F1-Ntg m -2.034 0.2282 -1.5843 -2.4837


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both -1.7143 0.1045 -1.5083 -1.9203
(B6.5XFAD x BXD100)F1-ADtg both -2.0795 0.2046 -1.6764 -2.4827
(B6.5XFAD x BXD100)F1-Ntg both -1.596 0.1647 -1.2714 -1.9205
(B6.5XFAD x BXD32)F1-ADtg both -1.4022 0.2084 -0.9917 -1.8128
(B6.5XFAD x BXD44)F1-ADtg both -1.8669 0.1165 -1.6374 -2.0965
(B6.5XFAD x BXD60)F1-ADtg both -1.4193 0.1712 -1.0819 -1.7566
(B6.5XFAD x BXD61)F1-ADtg both -1.8756 0.1761 -1.5287 -2.2226
(B6.5XFAD x BXD61)F1-Ntg both -2.0556 0.1545 -1.7511 -2.36
(B6.5XFAD x BXD62)F1-ADtg both -1.4133 0.2552 -0.9105 -1.9162
(B6.5XFAD x BXD62)F1-Ntg both -1.4522 0.233 -0.9932 -1.9112
(B6.5XFAD x BXD65)F1-ADtg both -1.6696 0.2046 -1.2665 -2.0728
(B6.5XFAD x BXD65)F1-Ntg both -1.8638 0.2017 -1.4662 -2.2613
(B6.5XFAD x BXD66)F1-ADtg both -1.6821 0.1864 -1.3149 -2.0493
(B6.5XFAD x BXD68)F1-ADtg both -1.4933 0.1761 -1.1464 -1.8403
(B6.5XFAD x BXD68)F1-Ntg both -2.0808 0.1977 -1.6913 -2.4703
(B6.5XFAD x BXD69)F1-ADtg both -1.7494 0.1545 -1.445 -2.0539
(B6.5XFAD x BXD69)F1-Ntg both -1.6718 0.1647 -1.3472 -1.9964
(B6.5XFAD x BXD70)F1-Ntg both -1.5628 0.233 -1.1038 -2.0218
(B6.5XFAD x BXD75)F1-ADtg both -2.0454 0.1804 -1.6899 -2.401
(B6.5XFAD x BXD77)F1-ADtg both -1.4609 0.1864 -1.0937 -1.8281
(B6.5XFAD x BXD77)F1-Ntg both -1.591 0.1318 -1.3313 -1.8507
(B6.5XFAD x BXD87)F1-ADtg both -1.6446 0.151 -1.3471 -1.9421
(B6.5XFAD x BXD89)F1-Ntg both -1.8467 0.2552 -1.3438 -2.3495
(B6.5XFAD x D2)F1-ADtg both -1.9333 0.1076 -1.7214 -2.1452
(B6.5XFAD x D2)F1-Ntg both -1.9207 0.1343 -1.6561 -2.1853




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA