MPD: Project measures / variables set: Gould2 FC_context

Project measures / variables set: Gould2 FC_context_acu

ID, description, units	MPD:47136 FC_context_acu acute group, percent immobility in training chamber, 24h after fear conditioning [%] nicotine study
Measures	• dose (mg): • control • 0.045 • 0.09 • 0.18
Data set, strains	Gould2 inbred 8 strains sex: m age: 8-12wks
Procedure	fear conditioning test
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0010529 contextual fear conditioning behavior trait VT:0010715 fear-related behavior trait VT:0010721 response to nicotine trait MP:0001469 abnormal contextual conditioning behavior MP:0003106 abnormal fear-related response MP:0020160 abnormal behavioral response to nicotine

Values Means Δ Means Z-scores

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Gould2 - acute group, percent immobility in training chamber, 24h after fear conditioning

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	3	4970.8002	1656.9334	10.883	< 0.0001
strain	7	64924.0428	9274.8633	60.9189	< 0.0001
dose:strain	21	16566.3577	788.8742	5.1815	< 0.0001
Residuals	326	49633.2904	152.2494

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gould2	47136	fear conditioning test	nicotine	acute group, percent immobility in training chamber, 24h after fear conditioning [%] dose control mg FC_context_acu_0	inbred	8	m
Gould2	47137	fear conditioning test	nicotine	acute group, percent immobility in training chamber, 24h after fear conditioning [%] dose 0.045 mg FC_context_acu_045	inbred	8	m
Gould2	47138	fear conditioning test	nicotine	acute group, percent immobility in training chamber, 24h after fear conditioning [%] dose 0.09 mg FC_context_acu_09	inbred	8	m
Gould2	47139	fear conditioning test	nicotine	acute group, percent immobility in training chamber, 24h after fear conditioning [%] dose 0.18 mg FC_context_acu_18	inbred	8	m